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Title G protein-coupled receptor-protein interactions / edited by Susan R. George, Brian F. O'Dowd.
Imprint Hoboken, N.J. : Wiley-Liss, c2005.
book jacket
 Life Sci. LIB  QU55 G1047 2005    AVAILABLE    30150100239299
Descript xviii,329 p. : ill. ; 26 cm.
Series Receptor biochemistry and methodology
Note Purification of the G protein-coupled receptor rhodopsin for structural studies -- Cooperativity in ligand binding to deduce receptor-receptor interaction -- Analysis of receptor-receptor interactions using time-resolved fluorescence resonance energy transfer -- Real-time imaging of GPCR-mediated arrestin translocation as a strategy to evaluate receptor-protein interactions -- Localization of G protein-coupled receptors and interacting proteins in membrane microdomains -- Identification of peptide ligand-binding domains within G protein-coupled receptors using photoaffinity labeling -- Analysis in real-time of the assembly and disassembly of soluble G protein-coupled-receptor-G protein complexes -- Approaches to studying membrane protein oligomerization : use of cysteine crosslinking strategies to analyze receptor-receptor interactions -- Co-immunoprecipitation as a strategy to evaluate receptor-receptor or receptor-protein interactions -- Use of MALDI-TOF and mass spectrometry in the evaluation of receptor-protein interactions -- Use of the yeast two-hybrid system to detect receptor-protein interactions -- GST fusion protein and pull-down strategies to evaluate receptor-receptor or receptor-protein interactions -- G protein fusion to monitor integral membrane protein-protein interactions -- Enzyme-linked immunosorbent assays as tools in studying interactions of G protein-coupled receptors -- Electrophysiological characterization of GPCR and ligand-gated channel cross-talk -- BRET as a strategy to evaluate receptor-receptor or receptor-protein interactions
Includes bibliographical references and index.
Subject GTP-Binding Proteins
Receptors, G-Protein-Coupled
Signal Transduction
Alt Author George, Susan R.
O'Dowd, Brian Francis, 1950-
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