LEADER 00000nam a2200493 i 4500 
001    978-981-10-0657-9 
003    DE-He213 
005    20160824102150.0 
006    m     o  d         
007    cr nn 008maaau 
008    160219s2016    si      s         0 eng d 
020    9789811006579|q(electronic bk.) 
020    9789811006562|q(paper) 
024 7  10.1007/978-981-10-0657-9|2doi 
040    GP|cGP|erda|dAS 
041 0  eng 
050  4 RS431.A64 
082 04 615.798|223 
100 1  Zou, Taotao,|eauthor 
245 10 Anti-cancer N-heterocyclic carbene complexes of gold(III),
       gold(I) and platinum(II) :|bthiol "switch-on" fluorescent 
       probes, thioredoxin reductase inhibitors and endoplasmic 
       reticulum targeting agents /|cby Taotao Zou 
264  1 Singapore :|bSpringer Singapore :|bImprint: Springer,
       |c2016 
300    1 online resource (xiii, 164 pages) :|billustrations (some
       color), digital ;|c24 cm 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
347    text file|bPDF|2rda 
490 1  Springer theses,|x2190-5053 
505 0  Introduction -- Experimental Section -- Gold(III) 
       Complexes Containing N-Heterocyclic Carbene Ligand Serve 
       as Dual Fluorescent Thiol "Switch-on" Probe and Anti-
       Cancer Agent -- A Binuclear Gold(I) Complex with Mixed 
       Bridging Diphosphine and Bis(N-Heterocyclic Carbene) 
       Ligands Shows Favorable Thiol Reactivity and Effectively 
       Inhibits Tumor Growth and Angiogenesis in Vivo -- 
       Luminescent Organoplatinum(II) Complexes Containing Bis(N-
       Heterocyclic Carbene) Ligands Selectively Target 
       Endoplasmic Reticulum and Induce Potent Phototoxicity -- 
       Summary and Evaluation 
650  0 Antineoplastic agents 
650  0 Cancer|xChemotherapy 
650  0 Gold|xTherapeutic use 
650 14 Chemistry 
650 24 Inorganic Chemistry 
650 24 Medicinal Chemistry 
650 24 Molecular Medicine 
650 24 Cancer Research 
710 2  SpringerLink (Online service) 
773 0  |tSpringer eBooks 
830  0 Springer theses 
856 40 |uhttp://dx.doi.org/10.1007/978-981-10-0657-9
       |zeBook(Springerlink)