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書名 Genetics, genomics and fish phenomics / edited by Nicholas S. Foulkes
出版項 [San Diego, California] : Academic Press : Elsevier Inc., 2016
國際標準書號 9780128048009
012804800X
9780128052167
0128052163
book jacket
說明 1 online resource (x, 262 pages) : illustrations
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
系列 Advances in genetics ; volume 95
Advances in genetics ; 95
附註 Text document in PDF and HTML format
System requirements: Adobe Acrobat Reader
Mode of access: World Wide Web
Genetics, Genomics and Fish Phenomics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions, with hhis volume focusing on genetics, genomics, and phenomics of fish
Includes bibliographical references and index
Online resource; title from title details screen (ScienceDirect, viewed August 12, 2016)
Front Cover; Genetics, Genomics and Fish Phenomics; Serial Editors; Genetics, Genomics and Fish Phenomics; Copyright; Contents; CONTRIBUTORS; One -- Studying the Evolution of the Vertebrate Circadian Clock: The Power of Fish as Comparative Models ; 1. INTRODUCTION; 1.1 What Are Circadian Clocks and Why Should We Study Them?; 1.2 Why Use Fish Genetic Models to Study Clocks?; 2. HOW DO FISH CLOCKS DIRECTLY SENSE LIGHT?; 2.1 Light-Inducible Gene Expression; 2.2 Peripheral Photoreceptors; 3. HOW DO FISH (AND CLOCKS) ADAPT DURING EVOLUTION UNDER PERPETUAL DARKNESS?; 3.1 Different Cave Environments
3.2 Blind Clocks in Phreatichthys andruzzii3.3 Differences Between Surface and Cave Clocks in Astyanax; 3.4 Has the Astyanax Light-Response Altered Within Cave Strains?; 3.5 Astyanax in the Field; 3.6 Cavefish Sleep, Activity, and Metabolism; 4. OUTLOOK; ACKNOWLEDGMENTS; REFERENCES; Two -- Genomic and Transcriptomic Approaches to Study Cancer in Small Aquarium Fish Models ; 1. INTRODUCTION; 2. CANCER MODELS IN FISH; 3. GENOMIC APPROACHES; 4. TRANSCRIPTOMIC APPROACHES; 4.1 Melanoma; 4.2 Rhabdomyosarcoma; 4.3 Hepatocellular Carcinoma; 5. OUTLOOK; ACKNOWLEDGMENTS; REFERENCES
Three -- Gal4 Driver Transgenic Zebrafish: Powerful Tools to Study Developmental Biology, Organogenesis, and Neurosc ... 1. INTRODUCTION; 2. TOL2-MEDIATED TRANSGENESIS IN ZEBRAFISH; 3. THE GAL4-UAS SYSTEM IN ZEBRAFISH; 3.1 The Emergence of the Gal4-UAS System in Zebrafish; 3.2 Tol2-Mediated Gal4 Gene Trapping and Enhancer Trapping; 3.3 Additional Improvements in the Gal4-UAS System; 4. APPLICATIONS OF GAL4 DRIVERS; 4.1 Inhibition of Neuronal Activities via Targeted Expression of a Neurotoxin Gene; 4.2 Visualization of Neuronal Activities by Calcium Imaging
4.3 Genetic Dissection of the Motor System4.4 The Architecture of Cerebellar Neural Circuits; 4.5 Proliferation and Differentiation of the Lateral Line System; 4.6 Spatiotemporal Functions of Notch Signaling; 5. CONCLUSION; ACKNOWLEDGMENTS; REFERENCES; Four -- Whole-Organism Cellular Pathology: A Systems Approach to Phenomics ; 1. INTRODUCTION; 1.1 Phenotype; 1.2 Phenomics and Phenome Projects; 1.3 Phenotype Omission Error; 1.4 Stereomicroscopy; 1.5 Molecular Imaging Versus Pan-Cellular Phenotyping; 1.6 Why Histological Phenotyping?; 2. LESSONS FROM LIGHT MICROSCOPY
2.1 Early Tissue Phenotyping2.2 Histological Phenotyping in Medicine; 2.3 Histological Phenotyping in Zebrafish; 2.3.1 Method and Tool Development for Zebrafish Histology; 2.3.2 Lessons From Creating a Web-Based Histology Atlas; 2.3.3 Lessons From Phenotyping Zebrafish Using Histology; 2.3.3.1 From a Histological Mutagenesis Screen; 2.3.3.2 The Potential Utility of Volumetric Data; 2.3.3.3 From a Histological Screen of Existing Mutants Found by Stereomicroscopy; 3. WHOLE-ORGANISM CELLULAR PATHOLOGY AS A SYSTEMS APPROACH TO PHENOMICS; 3.1 The Need for Whole-Organism Cellular Pathology
鏈接 Print version: Dunlap, Jay C. Genetics, Genomics and Fish Phenomics Saint Louis : Elsevier Science,c2016 9780128048009
主題 Fishes -- Genetics
Electronic books
Electronic books
Alt Author Foulkes, Nicholas S., editor
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