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書名 Systems biomedicine [electronic resource] : concepts and perspectives / edited by Edison T. Liu, Douglas A. Lauffenburger
出版項 London : Academic, 2009
國際標準書號 9780123725509
012372550X
book jacket
說明 1 online resource
附註 I. Foundations of Systems Biology -- Genomic Technologies for Systems Biology -- Proteomic Technologies -- II. Computational Modeling of Biological Systems -- Dynamic Systems Analysis -- Spatio-temoral Modeling of Cellular Systems -- High-level modeling of biological networks -- High-Performance Computing -- Modeling Software -- III. Network Biology -- Protein Interaction Networks -- Signaling Networks with Modeling Strategies -- Protein networks in integrin-mediated adhesions -- Network Imaging -- RNAi networks -- IV. Integrative Biology of Higher Biosystems -- Signal Processing and Integration During Development -- Systems Biology and Stem Cell Biology -- Application of immunologic modeling in drug discovery and development -- V. Systems Medicine Applications -- Systems Pharmacology
Systems biology is a critical emerging field that seeks to define the interactions of all biological components by examining underlying biochemical and genetic processes. It is a discipline that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. Systems Biomedicine is organized around foundations, computational modelling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon
Description based on print version record
Elsevier
鏈接 Print version: Systems biomedicine. London : Academic, 2009 9780123725509 012372550X (OCoLC)432405781
主題 Systems biology
Medical sciences -- Computer simulation
Systems Biology
Computer Simulation
Electronic books
Alt Author Liu, Edison T
Lauffenburger, Douglas A
ScienceDirect (Online service)
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