| 說明 |
xv, 284 pages : illustrations, graphs, tables ; 24 cm |
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text txt rdacontent |
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unmediated n rdamedia |
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volume nc rdacarrier |
| 附註 |
Includes bibliographical references and index |
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Introduction: What is molecular evolution? -- Gene structure and mutation. DNA sequences ; Gene structure ; Genetic codes ; Mutation ; Problems -- Dynamics of genes in populations. Changes in allele frequencies ; Natural selection ; Random genetic drift ; Effective population size ; Gene substitution ; Genetic polymorphism ; The Neo-Darwinian theory and the neutral mutation hypothesis ; Problems -- Evolutionary change in nucleotide sequences. Nucleotide substitution in a DNA sequence ; Number of nucleotide substitutions between two DNA sequences ; Alignment of nucleotide and amino acid sequence ; Indirect estimation of the number of nucleotide substitutions ; Problems -- Rates and patterns of nucleotide substitution. Rates of nucleotide substitution ; Causes of variation in substitution rates ; A case of positive selection : lysoazyme in cows and langurs ; Molecular clocks ; Rates of substitution in organelle DNA ; Pattern of nucleotide substitution in pseudogenes ; Nonrandom usage of synonymous codons ; Problems |
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Molecular phylogeny. Impact of molecular data on phylogenetic studies ; Phylogenetic trees ; Methods of tree reconstruction ; Phenetics versus cladistics ; Estimation of branch lengths ; Rooting unrooted trees ; Estimation of species-divergence times ; Clades ; Phylogeny of humans and apes ; Endosymbiotic origin of mitochondria and chloroplasts ; Molecular paleontology ; The dusky seaside sparrow : a lesson in conservation biology ; Problems -- Evolution by gene duplication and exon shuffling. Types of DNA duplication ; Domains and exons ; Domain duplication and gene elongation ; Formation of gene families and the acquisition of new functions ; Nonfunctionalization of duplicate genes ; Dating gene duplications ; The globin superfamily of genes ; Exon shuffling ; Alternative pathways for producing new functions ; Concerted evolution of multigene families ; Problems -- Evolution by transposition. Transposition and retroposition ; Transposable elements ; Retrosequences ; Effects of transposition on the host genome ; Hybrid dysgenesis ; Transposition and speciation ; Evolutionary dynamics of transposable-element copy number ; Horizontal gene transfer ; Problems -- Genome organization and evolution. C values ; Evolution of genome size in bacteria ; Genome size of eukaryotes and the C-value paradox ; The repetitive structure of the eukaryotic genome ; Mechanisms for increasing genome size ; Maintenance of nongenic DNA ; GC content in bacteria ; Compositional organization of the vertebrate genome ; Problems |
| 鏈接 |
Online version: Li, Wen-Hsiung, 1942- Fundamentals of molecular evolution. Sunderland, Mass. : Sinauer Associates, ©1991 (OCoLC)904224865
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| 主題 |
Molecular evolution
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Biological Evolution
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Molecular Biology
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Molecular Sequence Data
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Molecular evolution
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| Alt Author |
Graur, Dan, 1953-
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