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書名 Vascular Effects of Hydrogen Sulfide [electronic resource] : Methods and Protocols / edited by Jerzy Bełtowski
出版項 New York, NY : Springer New York : Imprint: Humana, 2019
國際標準書號 9781493995288 978-1-4939-9528-8
國際標準號碼 10.1007/978-1-4939-9528-8 doi
book jacket
版本 1st ed. 2019
說明 X, 221 p. 70 illus., 47 illus. in color. online resource
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
text file PDF rda
系列 Methods in Molecular Biology, 1064-3745 ; 2007
Methods in Molecular Biology ; 2007
附註 Synthesis, Metabolism, and Signaling Mechanisms of Hydrogen Sulfide: An Overview -- Lanthionine and Other Relevant Sulfur Amino Acid Metabolites: Detection of Prospective Uremic Toxins in Serum by Multiple Reaction Monitoring Tandem Mass Spectrometry -- Analysis of Vascular Hydrogen Sulfide Biosynthesis -- Measurement of Protein Persulfidation: Improved Tag-Switch Method -- ProPerDP: A Protein Persulfide Detection Protocol -- Vascular Effects of H2S-Donors: Fluorimetric Detection of H2S Generation and Ion Channel Activation in Human Aortic Smooth Muscle Cells -- In Vitro Measurement of H2S-Mediated Vasoactive Responses -- In Vivo Measurement of H2S, Polysulfides, and 'SSNO-mix'-Mediated Vasoactive Responses and Evaluation of 10 Hemodynamic Parameters from Rat Arterial Pulse Waveform -- Simultaneous Measurements of Tension and Free H2S in Mesenteric Arteries -- The Relaxant Mechanisms of Hydrogen Sulfide in Corpus Cavernosum -- Pharmacological Tools for the Study of H2S Contribution to Angiogenesis -- Central Administration of H2S Donors for Studying Cardiovascular Effects of H2S in Rats -- Colonic Delivery of H2S Donors for Studying Cardiovascular Effects of H2S in Rats -- Measurements for Sulfide-Mediated Inhibition of Myeloperoxidase Activity -- Vascular Myography to Examine Functional Responses of Isolated Blood Vessels
This book explores techniques for exploring hydrogen sulfide (H2S) and its effects on the vascular system through numerous experimental animal models and vascular preparations. Alterations of vascular H2S generation/signaling may be involved in the pathogenesis of systemic and pulmonary arterial hypertension, ischemic heart disease, ischemic stroke, preeclampsia, and erectile dysfunction, and H2S also serves as an attractive target for pharmacotherapy of cardiovascular diseases, as well as possible effects on cancer, wound healing, and diabetic retinopathy, among other pathologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Vascular Effects of Hydrogen Sulfide: Methods and Protocols is an ideal aid for scientists working to extend our knowledge in this valuable and wide-ranging field of study
Host Item Springer eBooks
鏈接 Printed edition: 9781493995271
Printed edition: 9781493995295
Printed edition: 9781493995301
主題 Molecular biology
Pharmaceutical technology
Cardiovascular system
Molecular Medicine.
Pharmaceutical Sciences/Technology.
Cardiovascular Biology.
Alt Author Bełtowski, Jerzy. editor. Editor.
SpringerLink (Online service)
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