MARC 主機 00000nam a2200421 i 4500 
001    MCPB0006410 
006    m     o  d         
007    cr cn||||||||| 
008    190828s2018    cau     ob    000 0 eng d 
020    1615047751 
020    161504776X 
020    1615047778 
020    9781615047758 
020    9781615047765 
020    9781615047772 
040    iG Publishing|beng|eaacr2|ciG Publishing 
041 0  eng 
050 00 QP249 
082 04 617.4610592 
100 1  Kopp, Ulla C 
245 10 Neural control of renal function|h[electronic resource] /
       |cUlla C. Kopp 
250    2nd ed 
260    San Rafael, California :|bMorgan & Claypool Life Sciences,
       |c2018 
300    1 online resource (121 p.) 
490 1  Colloquium Series on Integrated Systems Physiology: From 
       Molecule to Function to Disease 
504    Includes bibliographical references and index 
505 0  Neural control of renal function, second edition -- 
       Colloquium Digital Library of Life Sciences -- Colloquium 
       Series on Integrated Systems Physiology: From Molecule to 
       Function to Disease -- Abstract -- Contents -- Preface -- 
       Acknowledgments -- Part I. Efferent Renal Sympathetic 
       Nerves -- Chapter 1. Introduction -- Chapter 2. 
       Neuroanatomy -- Chapter 3. Neural Control of Renal 
       Hemodynamics -- Chapter 4. Neural Control of Renal Tubular
       Function -- Chapter 5. Neural Control of Renin Secretion 
       Rate -- Part II. Afferent Renal Sensory Nerves -- Chapter 
       6. Introduction -- Chapter 7. Neuroanatomy -- Chapter 8. 
       Renorenal Reflexes -- Chapter 9. Mechanisms Involved in 
       the Activation of Afferent Renal Sensory Nerves -- Chapter
       10. Efferent Renal Sympathetic and Afferent Renal Nerves -
       - Part III. Pathophysiological States -- Chapter 11. 
       Conclusions -- References -- Author Biography 
520 3  The kidney is innervated with efferent sympathetic nerve 
       fibers reaching the renal vasculature, the tubules, the 
       juxtaglomerular granular cells, and the renal pelvic wall.
       The renal sensory nerves are mainly found in the renal 
       pelvic wall. Increases in efferent renal sympathetic nerve
       activity reduce renal blood flow and urinary sodium 
       excretion by activation of α1-adrenoceptors and increase 
       renin secretion rate by activation of β1-adrenoceptors. In
       response to normal physiological stimulation, changes in 
       efferent renal sympathetic nerve activity contribute 
       importantly to homeostatic regulation of sodium and water 
       balance. The renal mechanosensory nerves are activated by 
       stretch of the renal pelvic tissue produced by increases 
       in renal pelvic tissue of a magnitude that may occur 
       during increased urine flow rate. Under normal conditions,
       the renal mechanosensory nerves activated by stretch of 
       the sensory nerves elicits an inhibitory renorenal reflex 
       response consisting of decreases in efferent renal 
       sympathetic nerve activity leading to natriuresis. 
       Increasing efferent sympathetic nerve activity increases 
       afferent renal nerve activity which, in turn, decreases 
       efferent renal sympathetic nerve activity by activation of
       the renorenal reflexes. Thus, activation of the afferent 
       renal nerves buffers changes in efferent renal sympathetic
       nerve activity in the overall goal of maintaining sodium 
       balance. In pathological conditions of sodium retention, 
       impairment of the inhibitory renorenal reflexes 
       contributes to an inappropriately increased efferent renal
       sympathetic nerve activity in the presence of sodium 
       retention. In states of renal disease or injury, there is 
       a shift from inhibitory to excitatory reflexes originating
       in the kidney. Studies in essential hypertensive patients 
       have shown that renal denervation results in long-term 
       reduction in arterial pressure, suggesting an important 
       role for the efferent and afferent renal nerves in 
       hypertension 
650  0 Kidneys|xPhysiology 
650  0 Kidneys|xInnervation 
650  0 Kidneys|xDiseases 
650  0 Science 
650  0 Life Sciences 
650  0 Anatomy & Physiology 
700 1  Granger, D. Neil,|eeditor 
700 1  Granger, Joey P.,|eeditor 
830  0 Colloquium Series on Integrated Systems Physiology : From 
       Molecule to Function to Disease 
856 40 |uhttp://portal.igpublish.com/iglibrary/search/
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