Title Genetic dissection of complex traits [electronic resource] / edited by D.C. Rao, C. Charles Gu
Imprint London ; Burlington, MA : Academic Press, 2008
book jacket
Edition 2nd ed
Descript 1 online resource (xxvii, 760 p.) : ill
tekst txt rdacontent/dut
computer c rdamedia/dut
online bron cr rdacarrier/dut
Series Advances in genetics, 0065-2660 ; 60
Advances in genetics ; 60
Note Previous ed.: 2001
Includes bibliographical references and Index
1. An overview of the genetic dissection of complex traits / D.C. Rao -- 2. Familial resemblance and heritability / Treva K. Rice -- 3. Linkage and association: basic concepts / Ingrid B. Borecki and Michael A. Province -- 4. Definition of phenotype / Mary K. Wojczynski and Hemant K. Tiwari -- 5. Genotyping platforms for mass-throughput genotyping with SNPs, including human genome-wide scans / Karen Maresso and Ulrich Broeckel -- 6. Genotyping errors and their impact on genetic analysis / Michael B. Miller, Karen Schwander, and D.C. Rhao -- 7. Model-based methods for linkage analysis / John P. Rice, Nancy L. Saccone, and Jonathan Corbett -- 8. Contemporary model-free methods for linkage analysis / Laura Almasy and John Blangero -- 9. DNA sequence-based phenotypic association analysis / Nicholas J. Schork, Jennifer Wessel, and Nathalie Malo
10. Family-based methods for linkage and association analysis / Nan M. Laird and Christoph Lange -- 11. Searching for additional disease loci in a genomic region / Glenys Thomson, Lisa F. Barcellos, and Ana M. Valdes -- 12. Methods for handling multiple testing / Treva K. Rice, Nicholas J. Schork, and D.C. Rao -- 13. Meta-analysis methods / Thomas A. Trikalinos, Georgia Salanti, Eias Zintzaras, and John P.A. Ioannidis -- 14. Haplotype-association analysis / Nianjun Liu, Kui Zhang, and Hongyu Zhao -- 15. Characterization LD structures and the utility of HapMap in genetic association studies / C. Charles Gu, Kai Yu, and D.C. Rao -- 16. Associations among multiple markers and complex disease: models, algorithms, and applications / Themistocles L. Assimes, Adam B. Olshen, Balasubramanian Narasimhan, and Richard A. Olshen
17. Study designs for genome-wide association studies / Peter Kraft and David G. Cox -- 18. Ethical, legal, and social implications of biobanks for genetics research / Susanne B. Haga and Laura M. Beskow -- 19. Admixture mapping and the role of population structure for localizing disease genes / Xiaofeng Zhu, Hua Tang, and Neil Risch -- 20. Integrating global gene expression analysis and genetics / Clarles R. Farber and Aldons J. Lusis -- 21. A systems biology approach to drug discovery / Jun Zhu, Bin Zhang, and Eric E. Schadt -- 22. The promise of composite likelihood methods for addressing computationally intensive challenges / Na Li -- 23 Comparative genomics for detecting human disease genes / Carol Moreno, Jozef Lazar, Howard J. Jacob, and Anne E. Kwitek -- 24. From genetics to mechanism of disease liability / Andreas Rohrwasser, Paul Lott, Robert B. Weiss, and Jean-Marc Lalouel -- 25. Into the Post-HapMap era / Newton E. Morton
Description based on print version record
The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines
Link Print version: Genetic dissection of complex traits. 2nd ed. London ; Burlington, MA : Academic Press, 2008 9780123738837 0123738830 (OCoLC)183915350
Subject Medical genetics
Syndromes -- Genetic aspects
Genetic epidemiology
Electronic books
Genetica. gtt
Electronic books
Alt Author Rao, D. C. (Dabeeru C.)
Gu, C. Charles