Title Applications of transition metal catalysis in drug discovery and development [electronic resource] : an industrial perspective / edited by Matthew L. Crawley, Barry M. Trost
Imprint Hoboken, N.J. : John Wiley & Sons, 2012
book jacket
Descript 1 online resource (xviii, 356 p.)
Note Includes bibliographical references and index
Applications of TRANSITION METAL CATALYSIS in Drug Discovery and Development; Contents; Preface; Contributors; About the Authors; 1 Transition Metal Catalysis in the Pharmaceutical Industry; 1.1 Overview of Catalysis; 1.2 Transition Metal Catalysis in the Pharmaceutical Industry; 1.2.1 Cross-Couplings for the Formation of Carbon-Carbon Bonds; 1.2.2 Cross-Couplings for the Formation of Carbon-Heteroatom Bonds; 1.2.3 Asymmetric Hydrogenation; 1.2.4 Oxidative Catalysis; 1.2.5 Asymmetric Addition Reactions; 1.2.6 Metathesis; 1.3 Challenges in Taking Catalysis to Industrial Scales
"This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development."--Provided by publisher
Description based on print version record
Subject Catalysis
Transition metals
Pharmacy
Drug Discovery
Catalysis
Pharmaceutical Preparations -- chemistry
Transition Elements
Alt Author Crawley, Matthew L
Trost, Barry M