作者 Jabbour, Nicolas
書名 Transfusion-Free Medicine and Surgery
出版項 Hoboken : John Wiley & Sons, Incorporated, 2014
©2013
國際標準書號 9781118554692 (electronic bk.)
9780470674086
book jacket
版本 2nd ed
說明 1 online resource (378 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
附註 Cover -- Title Page -- Copyright -- Contents -- Contributors -- Preface -- Chapter 1 History of blood transfusion and patient blood management -- Introduction -- Blood: early beliefs and practice -- Blood transfusion -- Transfusion with animal blood -- First human blood transfusion -- Karl Landsteiner to the twenty-first century -- New transfusion issues emerge -- The new paradigm -- References -- Chapter 2 The ethical complexities of transfusion-free medicine, surgery and research -- Introduction -- Ethics and informed consent -- Children, assent, and consent -- Professionalism and transfusion-free practices -- Jehovah's witnesses -- Organ transplantation -- Research ethics -- References -- Chapter 3 Transfusion therapy-Balancing the risks and benefits -- Introduction/overview -- The clinical utility of transfusion therapy -- Red blood cell transfusion -- Platelet transfusions -- Plasma component therapy -- Cryoprecipitate -- Transfusion-related adverse reactions -- Hemolytic transfusion reactions -- TRALI -- Sepsis -- Summary and conclusions -- References -- Chapter 4 The physiology of anemia and the threshold for blood transfusion -- Introduction -- Etiologies of anemia -- Physiologic response to anemia -- The transfusion threshold -- Risks of blood transfusion -- Infectious complications -- TRALI -- TACO -- Hemolytic reactions -- Febrile reactions -- Metabolic effects -- Immunological effects -- Summary -- References -- Chapter 5 Blood transfusion in surgery -- Introduction -- The cost-effectiveness of blood products: a surgical perspective -- Pre-operative optimization of the surgical patient -- Intra-operative approach to blood conservation -- A. Surgical judgment -- B. Surgical technique -- C. Intra-operative cell salvage (ICS) -- D. Acute normovolemic hemodilution (ANH) -- E. Anesthesia management -- F. Coagulation management
Post-operative care -- Trends in transfusion-free surgery -- Conclusion -- References -- Chapter 6 Current view of coagulation system -- Normal hemostasis -- Vascular phase -- Platelet phase -- Coagulation phase -- Fibrin formation -- Fibrinolysis -- Regulation of hemostasis -- Abnormal hemostasis -- Congenital hemostatic disorders -- Acquired hemostatic disorders -- Evaluation of hemostasis -- History and physical examination -- Coagulation tests -- Preoperative screening tests -- Thromboelastography -- Rotational thromboelastometry (ROTEM®) -- Management of intraoperative coagulation -- Clinical coagulation -- Coagulation management -- Hemostatic drug therapy -- Prolysins (tPA, urokinase, and streptokinase) -- Antifibrinolytics -- Procoagulants -- Anticoagulants -- References -- Chapter 7 Topical hemostatic agents -- Introduction -- History of hemostatics -- The biology of hemostasis -- Hemostasis in surgery -- Safety of hemostatics -- Topical hemostatics -- Passive agents -- Adhesive hemostatics (fibrin glues) -- Surgical settings -- Topical hemostatics (Passive agents) -- Collagen-based products -- Cellulose-based products -- Gelatin agents -- References -- Chapter 8 Intraoperative strategies for transfusion-free medicine -- Introduction -- General considerations -- Autologous blood -- Acute normovolemic (isovolemic) hemodilution -- Preoperative autologous donation -- Intraoperative blood salvage -- Pharmacologic agents for blood conservation -- DDAVP -- Antifibrinolytic agents -- Recombinant factor VIIa -- Miscellaneous agents -- Human recombinant erythropoietin -- Controlled hypotension -- Sodium nitroprusside (SNP) -- Calcium channel antagonists -- Summary -- References -- Chapter 9 Post-operative management in transfusion-free medicine and surgery in the ICU -- Introduction -- Anemia in the ICU -- Role of transfusion in resuscitation
Monitoring the adequacy of oxygenation -- Cardiac output -- SvO2 -- O2ER -- Blood lactate -- Regional markers of tissue oxygenation -- Reducing transfusion requirements -- Reducing phlebotomy losses -- Minimizing oxygen consumption -- Increasing CO and DO2 -- Erythropoietin -- Other factors -- Conclusion -- References -- Chapter 10 The changing transfusion practice of neonatal and pediatric surgery -- Introduction -- Transfusion considerations specific to the pediatric population -- Strategies to limit need or transfusion -- Use of recombinant human erythropoietin -- Autotransfusion strategies -- Application of hemostatic agents -- Perioperative approaches -- Physician awareness -- Applications of transfusion-limiting strategies to specific surgical situations -- Neonatal surgery -- Cardiac surgery -- Orthopedic surgery -- Craniosynostosis surgery -- Hepatic surgery -- Burn surgery -- Trauma surgery -- Anemia of prematurity -- Anemia in the PICU -- Anemia of oncologic disease -- Conclusion -- Acknowledgements -- References -- Chapter 11 Current management of anemia in oncology -- Overview -- Epidemiology and pattern of treatment -- Prognostic significance and rationale for correcting anemia in oncology -- Pathophysiology of anemia in cancer patients -- Diagnostic evaluation and risk assessment -- Treatment options -- Erythropoiesis stimulating agents (ESAs) -- Physiologic basis for ESA use in oncology -- Benefits of ESAs -- Risks of ESAs -- Iron supplementation with ESA -- Peripheral red blood cell (PRBC) transfusion -- Benefits -- Risks -- Trend of increased transfusions because of decreased ESA use -- Current recommendations -- Evolving concepts -- Conclusion -- References -- Chapter 12 Artificial blood -- Background -- Basics of blood oxygen transportation -- Defining the need for artificial oxygen carriers -- Hb-based oxygen carriers
Perfluorocarbons -- Conclusion -- References -- Chapter 13 Translational strategies to minimize transfusion requirement in liver surgery and transplantation: Targeting ischemia-reperfusion injury -- Introduction -- Role of ischemia-reperfusion injury in liver surgery and transplantation -- Surgical and pharmacological strategies to mimimize I/R injury in liver surgery and transplantation -- Static liver preservation -- Pharmacological treatments -- Machine perfusion -- Normothermic machine perfusion (NMP) -- Hypothermic machine perfusion (HMP) -- Surgical strategies -- Conclusion -- Abbreviations -- References -- Chapter 14 Legal and administrative issues related to transfusion-free medicine and surgery programs -- Introduction -- History of Jehovah's Witnesses and blood -- Acceptable products, treatments, and procedures -- Autologous procedures and equipment -- Organ transplantation -- Overview of legal principles related to refusal of blood -- A. Refusal of blood as life-sustaining treatment -- B. Specific issues related to refusal of blood in J.W. -- Disagreeing family members -- Minors -- Mature and emancipated minors -- Evolution of bloodless programs -- Early pioneers of bloodless medicine and surgery -- Transfusion free "bloodless" program implementation -- Legal structure of bloodless program -- Consent: liability of physician and hospital -- Confirming a patient's decision to refuse blood -- Policies and procedures -- Future expansion of transfusion-free programs -- References -- Chapter 15 Basic principles of bloodless medicine and surgery -- Questionnaire -- Index -- EULA
This book aims to be a guide to the practice of blood conservation. The first chapter discusses the legal and administrative aspects of bloodless medicine describing the legal principles and practical issues relatd to refusal of transfusion. The second is on balancing the risks and benefits of transfusion includes clinical vignettes of appropriate and inappropriate transfusion. The remainder of the book covers the principles and practice of bloodless medicine, including a chapter on the scientific issues of haemostasis and the investigation of bleeding idsorders. The book concludes with chapters on blood conservation in neonatal and paediatric surgery, the costs associated with blood transfusion and the quest for artifical blood. New chapters will be included to address blood utilization in oncology and geriatric patients
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
鏈接 Print version: Jabbour, Nicolas Transfusion-Free Medicine and Surgery Hoboken : John Wiley & Sons, Incorporated,c2014 9780470674086
主題 Bloodless Medical and Surgical Procedures
Electronic books