書名 Nutrition and cancer / Edited by Aitziber Buqu⥬ Lorenzo Galluzzi
出版項 Cambridge, MA : Academic Press, 2022
國際標準書號 9780323903899
book jacket
說明 1 online resource
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
系列 International review of cell and molecular biology ; volume 373
International review of cell and molecular biology ; v. 373
附註 Print version record
Intro -- Nutrition and Cancer -- Copyright -- Contents -- Contributors -- Emergent impact of lifestyle on tumor progression and response to therapy -- Acknowledgments -- Conflict of interest -- References -- Chapter One: Modifying dietary amino acids in cancer patients -- 1. Introduction -- 2. Reducing availability of NEAAs as an anti-cancer approach -- 3. Role of essential AAs in cancer biology -- 4. Altering dietary protein to limit tumor growth and enhance cancer therapy -- 5. Role of bacteria in mediating the pro-tumorigenic effects of dietary AAs
6. Current recommendations for protein intake in cancer patients -- 7. Considerations for evaluating the impact of modifying AA intake on treatment response and outcomes in patients with cancer -- Acknowledgments -- Conflicts of interest -- References -- Chapter Two: Targeting amino acid metabolism in cancer -- 1. Introduction -- 2. Asparagine -- 2.1. Asparagine synthetase (ASNS) -- 2.1.1. Catalytic function and structure of ASNS -- 2.1.2. ASNS deficiency -- 2.1.3. ASNS regulation -- 2.2. L-asparaginase (ASNase) -- 2.2.1. ASNase in leukemias and lymphomas -- 2.2.2. ASNase in solid tumors
2.2.3. Glutaminase activity of ASNase -- 2.2.4. Limits of the ASNase therapy -- 3. Arginine -- 3.1. Metabolism of arginine -- 3.2. Arginine-nitric oxide pathway -- 3.3. Arginine-ornithine-polyamine pathway -- 3.4. Suitable candidates for arginine-depleting enzyme therapies -- 3.5. Arginine deiminase -- 3.5.1. Arginine deiminase-based therapy -- 3.5.2. Limitations of arginine deiminase therapy -- 3.6. Arginase -- 3.6.1. Arginase therapy -- 3.6.2. Limitations of arginase therapy -- 4. Methionine -- 4.1. Methionine metabolism -- 4.2. The Hoffman effect -- 4.3. Methioninase
4.3.1. Methioninase therapy -- 5. Cysteine -- 5.1. Cysteine metabolism -- 5.2. Cyst(e)inase -- 5.2.1. Cyst(e)inase therapy -- 6. Concluding remarks -- Acknowledgments -- References -- Chapter Three: Fasting and cancer: from yeast to mammals -- 1. Introduction -- 2. Calorie restriction -- 3. Fasting and fasting mimicking diets -- 4. Fasting mimicking diets and cancer -- 4.1. Differential stress resistance -- 4.2. Differential stress sensitization -- 4.3. FMD and antitumor immunity -- 5. Fasting-mimicking diets and non-toxic interventions to kill cancer cells
5.1. FMD synergizes with high-dose vitamin C to kill KRAS-mutant cancer cells -- 5.2. FMD cycles potentiate hormone therapies and induce breast cancer regression -- 6. Fasting-mimicking diets in clinical oncology -- Acknowledgments -- References -- Chapter Four: Fasting and cancer responses to therapy -- 1. Introduction -- 2. Nutrients restriction in rodents and humans -- 3. Calorie restriction in cancer therapy -- 4. Alternative approaches to fasting and CR in cancer therapy -- 5. Conclusion -- Acknowledgments -- Conflicts of interest -- Authors contribution -- References
鏈接 Print version: NUTRITION AND CANCER. [Place of publication not identified] : ELSEVIER ACADEMIC PRESS, 2022 0323903886 (OCoLC)1273677495
主題 Cancer -- Nutritional aspects
Cancer -- Cytopathology
Cancer -- Cytopathology. fast (OCoLC)fst00845344
Cancer -- Nutritional aspects. fast (OCoLC)fst00845407
Electronic books
Alt Author Buqu⥬ Aitziber, editor
Galluzzi, Lorenzo, editor