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書名 Phenotypic screening : methods and protocols / edited by Bridget Wagner
出版項 New York, N.Y. : Humana Press ; Springer, [2018]
國際標準書號 9781493978472
book jacket
說明 1 online resource (xii, 280 pages) : illustrations (some color)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
系列 Methods in molecular biology, 1940-6029 ; 1787
Methods in molecular biology ; 1787
附註 Includes bibliographical references and index
Nutrient stress small-molecule screening platform for Escherichia coli / Sara S. El Zahed, Garima Kumar, Madeline Tong, and Eric D. Brown -- Validation and development of an Escherichia coli riboflavin pathway phenotypic screen hit as a small-molecule ligand of the flavin mononucleotide riboswitch / Carl J. Balibar, Artjohn Villafania, Christopher M. Barbieri, Nick Murgolo, Terry Roemer, Hao Wang, and John A. Howe -- Phenotypic screening of small molecules with antimalarial activity for three different parasitic life stages / Nobutaka Kato, Sandra March, Sangeeta N. Bhatia, and Matthias Marti -- Phenotypic screening for inhibitors of a mutant thrombopoietin receptor / Anna Ngo, Ann Koay, Christian Pecquet, Carmen C. Diaconu, David A. Jenkins, Andrew K. Shiau, Stefan N. Constantinescu, and Meng Ling Choong -- Cell-based assay for mitotic spindle orientation / Elina Glaubke and Holger Bastians -- Isolation of skeletal muscle stem cells for phenotypic screens for modulators of proliferation / Aaron C. Hinken and Andrew N. Billin -- Cell-based methods to identify inducers of human pancreatic beta-cell proliferation / Courtney A. Ackeifi, Ethan A. Swartz, and Peng Wang -- High-content imaging phenotypic screen for neurogenesis using primary neural progenitor cells / Li Sharon Wu and Jingjun Li -- Discovery of modulators of adipocyte physiology using fully functionalized fragments / Andrea Galmozzi, Christopher G. Parker, Bernard P. Kok, Benjamin F. Cravatt, and Enrique Saez -- Ancient genetic networks of obesity : whole-animal automated screening for conserved fat regulators / Wenfan Ke, Anna Drangowska-Way, Daniel Katz, Karsten Siller, and Eyleen J. O'Rourke -- Modulation of threat response in larval zebrafish / Andrew J. Rennekamp -- PLA-iRoCS pipeline for the localization of protein-protein interactions in situ / Taras Pasternak, William Teale, Thorsten Falk, Benedetto Ruperti, and Klaus Palme -- High-dimensional profiling : the theta comparative cell scoring method / Scott J. Warchal, John C. Dawson, and Neil O. Carragher -- Accessing the open PHACTS discovery platform with workflow tools / Daniela Digles, Andrei Caracoti, and Edgar Jacoby -- Quantitative prioritization of tool compounds for phenotypic screening / Yuan Wang and Jeremy L. Jenkins -- Quantitative systems pharmacology approach to infer pathways involved in complex disease phenotypes / Mark E. Schurdak, Fen Pei, Timothy R. Lezon, Diane Carlisle, Robert Friedlander, D. Lansing Taylor, and Andrew M. Stern -- Phenotype-based high-content screening using fluorescent chemical bioprobes : lipid droplets and glucose uptake quantification in live cells / Young-Hee Shin and Seung Bum Park -- Developing high-throughput assays to analyze and screen electrophysiological phenotypes / Jen Q. Pan, David Baez-Nieto, Andrew Allen, Hao-Ran Wang, and Jeffrey R. Cottrell -- Testing susceptibility of patient-derived organoid cultures to therapies : pharmacotyping / Richard A. Burkhart, Lindsey A. Baker, and Herve Tiriac -- Techniques to enable 1536-well phenotypic screening / Sinead Knight, Helen Plant, Lisa McWilliams, and Mark Wigglesworth
Online resource; title from PDF title page (SpringerProtocol, viewed May 8, 2018)
鏈接 Print version: Phenotypic screening. New York, N.Y. : Springer, 2018 9781493978465
主題 Drug development
Drug Discovery -- methods
Electronic books
Laboratory Manuals
Alt Author Wagner, Bridget K., editor
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