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書名 The molecular biology of photorhabdus bacteria / edited by Richard H. ffrench-Constant
出版項 Cham : Springer International Publishing : Imprint: Springer, 2017
國際標準書號 9783319527154 (electronic bk.)
9783319527147 (paper)
國際標準號碼 10.1007/978-3-319-52715-4 doi
book jacket
說明 1 online resource (x, 213 pages) : illustrations, digital ; 24 cm
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
text file PDF rda
系列 Current topics in microbiology and immunology, 0070-217X ; volume 402
Current topics in microbiology and immunology ; volume 402
附註 Insecticidal Toxin complexes from Photorhabdus luminescens -- Identifying anti-host effectors in Photorhabdus -- Flagellar regulation and virulence in the entomopathogenic bacteria Xenorhabdus nematophila and Photorhabdus luminescens -- Natural products from Photorhabdus and other entomopathogenic bacteria -- The regulation of secondary metabolism in Photorhabdus -- Quorum sensing and LuxR solos in Photorhabdus -- Insect immunity to entomopathogenic nematodes and their mutualistic bacteria -- Photorhabdus asymbiotica as an insect and human pathogen -- A review of clinical cases of infection with Photorhabdus asymbiotica -- A Practical Guide to Recombineering in Photorhabdus and Xenorhabdus
This book provides an essential update on the startling array of novel insecticidal toxins and drugs produced by the fascinating bacterium Photorhabdus. The respective chapters describe everything from the detailed molecular biology of the 'Toxin complexes' or Tc's to the complexity of insect immune response in relation to both the bacterium and its nematode vector. The volume covers both primary (toxin production and regulation) and secondary (natural product synthesis and regulation) metabolism and emphasises the potential use of toxins and drugs in both agriculture and medicine. It also discusses in detail two totally novel quorum sensing mechanisms and the likely role of LuxR solos in sensing the presence of different bacterial hosts. Lastly, the book explores the unique case of P. asymbiotica, which seems to have evolved the ability to infect both insects and humans. This synthesis proves that Photorhabdus truly does offer a 'gold mine' for the discovery of novel insecticidal proteins and novel natural products with potential uses in agriculture and medicine alike
Host Item Springer eBooks
主題 Luminous bacteria
Insect nematodes
Medical Microbiology
Alt Author ffrench-Constant, Richard H., editor
SpringerLink (Online service)
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