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書名 Resistance to molecular therapies for hepatocellular carcinoma / edited by Augusto Villanueva
出版項 Cham : Springer International Publishing : Imprint: Springer, 2017
國際標準書號 9783319561974 (electronic bk.)
9783319561967 (paper)
國際標準號碼 10.1007/978-3-319-56197-4 doi
book jacket
說明 1 online resource (xiii, 147 pages) : illustrations, digital ; 24 cm
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
text file PDF rda
系列 Resistance to targeted anti-cancer therapeutics, 2196-5501 ; volume 13
Resistance to targeted anti-cancer therapeutics ; volume 13
附註 Tumor Heterogeneity and Resistance to Targeted Therapies in Hepatocellular Carcinoma -- Modulating Immune Responses to Overcome Resistance in Hepatocellular Carcinoma -- Role of Tumor Microenvironment in Hepatocellular Carcinoma Resistance -- Contribution of the Cancer Stem Cell Phenotype to Hepatocellular Carcinoma Resistance -- Clinical and Preclinical Perspectives on Mechanisms of Sorafenib Resistance in Hepatocellular Carcinoma -- Radiological Assessment of Response to Palliative Treatments in Hepatocellular Carcinoma -- Sorafenib and Clinical Patterns of Resistance in hepatocellular carcinoma -- Overcoming Treatment Resistance in Hepatocellular Carcinoma: regorafenib and lessons from other malignancies
This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies
Host Item Springer eBooks
主題 Liver -- Cancer -- Chemotherapy
Drug resistance in cancer cells
Cancer Research
Alt Author Villanueva, Augusto, editor
SpringerLink (Online service)
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