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書名 DNA- and RNA-based computing systems / edited by Evgeny Katz
出版項 Weinheim, Germany : Wiley-VCH, [2021]
國際標準書號 9783527825424
3527825428
9783527825417
352782541X
9783527825400
3527825401
book jacket
版本 First edition
說明 1 online resource
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
附註 Includes bibliographical references and index
"The world's leading experts in biomolecular computing provide an overview of different DNA/RNA-based computing systems, including simple Boolean logic gates, multi-component logic networks, combinatorial calculators, cell-based systems, logic systems for biomedical analysis, and more. In doing so, they cover advances in unconventional computing, biochemistry, smart materials, biotechnology and nanotechnology. The book also discusses potential applications in biosensing and bioactuation, particularly for biomedical purposes"-- Provided by publisher
Description based on online resource; title from digital title page (viewed on April 20, 2021)
Cover -- Title Page -- Copyright -- Contents -- Preface -- Chapter 1 DNA Computing: Origination, Motivation, and Goals - Illustrated Introduction -- 1.1 Motivation and Applications -- 1.2 DNA- and RNA-Based Biocomputing Systems in Progress -- 1.3 DNA-Based Information Storage Systems -- 1.4 Short Conclusions and Comments on the Book -- References -- Chapter 2 DNA Computing: Methodologies and Challenges -- 2.1 Introduction to DNA Computing Methodologies -- 2.2 Key Developments in DNA Computing -- 2.2.1 Adleman Model -- 2.2.2 Lipton's Model -- 2.2.3 Smith's Model -- 2.2.4 Sakamoto's Model
2.2.5 Ouyang's Model -- 2.2.6 Chao's Model -- 2.2.7 DNA Origami -- 2.2.8 DNA-Based Data Storage -- 2.3 Challenges -- Acknowledgment -- References -- Chapter 3 DNA Computing and Circuits -- 3.1 From Theory to DNA Implementations -- 3.2 Application-Specific DNA Circuits -- Acknowledgments -- References -- Chapter 4 Connecting DNA Logic Gates in Computational Circuits -- 4.1 DNA Logic Gates in the Context of Molecular Computation -- 4.2 Connecting Deoxyribozyme Logic Gates -- 4.3 Connecting Gates Based on DNA Strand Displacement -- 4.4 Logic Gates Connected Via DNA Four-Way Junction (4WJ)
4.5 Conclusion -- References -- Chapter 5 Development of Logic Gate Nanodevices from Fluorogenic RNA Aptamers -- 5.1 Nucleic Acid: The Material of Choice for Nanotechnology -- 5.2 RNA Aptamers are Modular and Programmable Biosensing Units -- 5.3 Construction of RNA Nanoparticles with Integrated Logic Gate Operations Using Light-Up Aptamers -- 5.3.1 Implementation of MG-Binding RNA Aptamer to Design Binary Logic Gates -- 5.3.2 Implementation of MG-Binding RNA Aptamer and Broccoli RNA Aptamer to Design Half-Adder Circuit -- 5.4 Conclusion -- Acknowledgments -- References
Chapter 6 Programming Molecular Circuitry and Intracellular Computing with Framework Nucleic Acids -- 6.1 Framework Nucleic Acids -- 6.2 A Toolbox for Biomolecular Engineering of Living Systems -- 6.2.1 Biomolecular Scaffolds -- 6.2.2 Logic Units -- 6.2.3 Cell Entry Vehicles -- 6.2.4 Isothermal Construction -- 6.2.5 Targeting and Editing -- 6.2.6 Signal Readout -- 6.2.7 Triggers and Switches -- 6.2.8 Error Correction and Resilience -- 6.3 Targeted Applications -- 6.3.1 Drug Delivery -- 6.3.2 Cellular Imaging -- 6.3.3 Metabolic Engineering and Cellular Pathway Investigation
6.4 Nucleic Acid Nanotechnology-Enabled Computing Kernel -- 6.5 I/O and Human-Computer Interfacing -- 6.6 Information Storage -- 6.7 Perspectives -- 6.8 Conclusion -- 6.8.1 Terminology -- References -- Chapter 7 Engineering DNA Switches for DNA Computing Applications -- 7.1 Introduction -- 7.2 Selecting Recognition Element Based on Input -- 7.3 Engineering Switching Mechanisms -- 7.4 Engineering Logic Output Function Response -- 7.5 Optimizing Switch Response -- 7.6 Perspective -- Acknowledgments -- References -- Chapter 8 Fluorescent Signal Design in DNA Logic Circuits
8.1 Basic Signal Generation Strategies Based on DNA Structures
鏈接 Print version: DNA- and RNA-based computing systems First edition. Hoboken, NJ : Wiley-VCH, 2021. 9783527347209 (DLC) 2020027451
主題 Molecular computers
Ordinateurs mol⥣ulaires
Molecular computers fast (OCoLC)fst01024771
Electronic books
Electronic books
Alt Author Katz, Evgeny, editor
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