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Author Dale, Russell C
Title Inflammatory and Autoimmune Disorders of the Nervous System in Children
Imprint London : Mac Keith Press, 2010
©2010
book jacket
Descript 1 online resource (521 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Clinics in Developmental Medicine ; v.184-185
Clinics in Developmental Medicine
Note Intro -- Contents -- Authors Appointments -- Introduction -- Chapter 1 Inflammatory and Autoimmunity: a Nervous System Perspective -- Introduction -- Immune privilege versus immune surveillance -- Immune surveillance of the brain -- The immune and inflammatory responses in the brain -- autoimmune cellular responses within the brain -- autoimmune antibody responses within the brain -- Conclusions -- References -- Chapter 2 New Intermational Definitions for Centrral Nervous System Demyelination Syndromes in Children -- Introduction -- Acute disseminated encephalomyelitis (monophasic) -- Recurrent acute disseminated encephalomyelitis -- Multiphasic acute disseminated encephalomyelitis -- Neuromyelitis optica -- Clinically isolated syndrome -- Paediatric multiple sclerosis -- Discussion -- References -- Chaper 3 Acute Disseminated Encephalomyelitis -- Introduction -- Epidemiology -- Clinical features -- Neuroimaging features -- Proposed definitions -- Relapsing variants of acute disseminated encephalomyelitis -- acute disseminated encephalomyelitis, clinically isolated syndrome, and the -- Differentiating neuromyelitis optica from acute disseminated -- Differential diagnosis of acute disseminated encephalomyelitis -- Immunopathogenesis -- Management -- Prognosis and outcome -- Future directions -- References -- Chapter 4 Childhood Multiple Sclerosis -- Introduction -- Demographic features -- New clinical definition of multiple sclerosis -- Clinical features at onset -- Risk of relapse after a first episode of central nervous system demyelination -- Clinical course -- Investigation features -- Pathogenesis and environmental risk factors -- Management -- Prognosis and outcome -- Conclusions -- References -- Chapter 5 Multiple Sclerosis: an Adult Perspective -- Introduction -- Background -- Clinical features -- Definition -- Investigations
Pathophysiology -- Management -- Prognosis and outcome -- Future directions and controversies -- References -- Chapter 6 Transverse Myelitis -- Introduction -- Epidemiology -- Clinical features -- Investigation features -- Immunopathology -- Management -- Prognosis and outcome -- Future directions and controversies -- Summary and conclusions -- References -- Chapter 7 Optic Neuritis in Children -- Introduction -- Background -- Clinical features -- Treatment -- Outcome -- References -- Chapter 8 Sydenham Chorea -- Introduction -- Epidemiology -- Clinical features -- Aetiology and pathogenesis -- Diagnosis -- Prognosis and complications -- Management -- Prevention -- Conclusions -- References -- Chapter 9 Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infection -- Introduction -- Clinical features -- Immunopathology -- Management -- Conclusions -- References -- Chapter 10 Opsoclonus-Myoconus Syndrome -- Introduction -- Epidemiology -- Clinical features -- Investigation features -- Immunopathology -- Treatment and management -- Prognosis and outcome -- Controversies and future directions -- Summary and conclusions -- acknowledgements -- References -- Chapter 11 Other Immune-Mediated Extrapyramidal Movement Disorders -- Introduction -- Epidemiology -- Clinical Syndromes -- Future directions and controversies -- Summary and conclusions -- References -- Chapter 12 Postinfectious Ataxia and -- Introduction -- Definitions: acute cerebellar ataxia or acute cerebellitis? -- Epidemiology -- Clinical features -- Investigation features -- Management -- Prognosis and outcome -- Future directions and controversies -- Summary and conclusions -- References -- Chapter 13 Rasmussen Encephalitis -- Introduction -- Epidemiology -- Clinical features -- Clinical investigation features -- Differential diagnoses -- Pathology and pathogenesis
Management -- Prognosis and outcome -- Future directions and controversies -- Summary and conclusions -- References -- Chapter 14 Neuropsychiatric Manifestations of Childhood Systemic Lupus Erythematosus and Antiphospholid Syndrome -- Introduction -- Systemic lupus erythematosus -- Childhood antiphospholipid syndrome -- Future directions and controversies -- Summary and conclusions -- References -- Chapter 15 Central Nervous System Vasculitis -- Introduction -- Background -- Childhood primary angiitis of the central nervous system -- Large- and medium-vessel childhood primary angiitis of the central nervous system -- Small-vessel childhood primary angiitis of the central nervous system -- Secondary central nervous system vasculitis -- Systemic lupus erythematosus -- Infection-associated central nervous system vasculitis -- Postvaricella arteriopathy -- Differential diagnosis of central nervous system vasculitis -- Mimics of large- and medium-vessel vasculitis -- Mimics of small-vessel vasculitis -- Future directions and controversies -- Summary and conclusions -- References -- Chapter 16 Macrophage Activation Syndromes -- Introduction -- Common clinical, biological, and radiological features of acute macrophage -- Features specific to the different genetic entities -- Treatment -- Conclusions -- References -- Chapter 17 Aicardi-Goutieres Syndrome and Related Disorders -- Introduction -- Epidemiology -- Clinical features -- Diagnostic investigations -- Differential diagnosis -- Genetics -- Prognosis and outcome -- Pathogenesis -- Summary -- acknowledgements -- References -- Chapter 18 Neonatal-onset Multisystem Inflammatroy Disorder/Chronic Infantile Neurological Cutaneous Syndrome -- Introduction -- Epidemiology -- Clinical features -- Laboratory features -- Immunopathology -- Management -- Prognosis and outcome -- Future directions -- Conclusions
References -- Chapter 19 Folate Receptor Autoimmunity in Cerebral Folate Deficiency -- Introduction to folate metabolism -- Definition and overview of cerebral folate deficiency -- Epidemiology -- Clinical features -- Investigations -- Immunopathology -- Management -- Prognosis and outcome -- Future directions and controversies -- Summary and conclusions -- References -- Chapter 20 The Innate Immune System and Inflammatory Mechanisms in Neurodegenerative Disorders -- Background -- What is neuroinflammation? -- Primary localized glial activation -- Molecular effectors of inflammation -- Blood-brain barrier -- Future directions and concluding comments -- References -- Chapter 21 Glutamate Receptor Autoantibodies in Epilepsy, Systemic Lupus Erythematosus and Encephalitis -- Introduction: glutamate and glutamate receptor autoimmunity -- Glutamate receptor family -- Glutamate receptor autoantibodies in human diseases -- Epilepsy and 'autoimmune epilepsy' -- Glutamate/aMPa-GluR3 autoantibodies in epilepsy -- anti-aMPa and anti-NMDa autoantibodies do not cross-react -- Systemic lupus erthymatosus and neuropsychiatric systemic lupus erthymatosus -- Glutamate/NMDa-R2a/b autoantibodies in systemic lupus erythematosus -- autoantibodies to glutamate receptors in limbic and paraneoplastic encephalitis -- Towards drug discovery -- Acknowledgement -- References -- Chapter 22 Autoimmune Channelopathies and other Antibody-Associated Neurological Disorders -- Introduction -- Channels and receptors -- Peripheral neurological diseases -- Central nervous system -- General discussion -- Acknowledgements -- References -- Chapter 23 Childhood Autoimmune Myasthenia -- Introduction -- Clinical subtypes -- Childhood autoimmune myasthenia gravis -- Transient neonatal myasthenia -- Ocular myasthenia -- Prenatal myasthenia (causing arthrogryposis multiplex congenita)
lambert-eaton myasthenic syndrome -- Assessment -- Investigation of neuromuscular junction disorders -- Chapter 24 Guillan-Barre Syndrome and Chronic Inflammatory Demyelinating Polyneuropathy in Childhood -- Introduction -- Subacute inflammatory demyelinating polyneuropathy -- Chronic inflammatory demyelinating polyneuropathy -- Chronic relapsing axonal neuropathy -- Conclusions and future directions -- References -- Chapter 25 Dermatomyositis and Polymyositis -- Introduction -- Epidemiology and aetiology -- Immunopathogenesis -- Clinical features -- Constitutional symptoms -- Differential diagnosis -- Investigations and diagnostic criteria -- Management -- Disease monitoring -- Outcome -- Future directions -- References -- Chapter 26 Inflammatory Mechanisms in Genetic Neuromuscular Disorders -- Introduction -- Inherited diseases of the peripheral nervous system that affect children -- Inherited diseases of skeletal muscle that affect children -- Myositis with genetic predisposing factors that affect children -- Conclusions -- References -- Index
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Link Print version: Dale, Russell C Inflammatory and Autoimmune Disorders of the Nervous System in Children London : Mac Keith Press,c2010 9781898683667
Subject Pediatric neurology.;Neuroimmunology.;Inflammation.;Nervous system -- Diseases
Electronic books
Alt Author Vincent, Angela
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