LEADER 00000nam a2200469 i 4500 
001    978-3-030-21657-3 
003    DE-He213 
005    20201030135148.0 
006    m     o  d         
007    cr nn 008maaau 
008    200615s2020    sz      s         0 eng d 
020    9783030216573|q(electronic bk.) 
020    9783030216566|q(paper) 
024 7  10.1007/978-3-030-21657-3|2doi 
040    GP|cGP|erda 
041 0  eng 
050  4 RB127|b.G466 2020 
082 04 616.0472|223 
245 00 Genomics of pain and co-morbid symptoms /|cedited by Susan
       G. Dorsey, Angela R. Starkweather 
264  1 Cham :|bSpringer International Publishing :|bImprint: 
       Springer,|c2020 
300    1 online resource (ix, 255 pages) :|billustrations, 
       digital ;|c24 cm 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
347    text file|bPDF|2rda 
505 0  Chapter 1. Pain physiology (defining acute and chronic 
       pain) -- Chapter 2. Neurobiology of nociception (anatomy 
       of ascending and descending systems) -- Chapter 3. 
       Genetics of pain and co-occuring symptoms -- Chapter 4. 
       Sex differences and pain genomics -- Chapter 5. Systems 
       biology/multi-omis approaches to pain and co-occuring 
       symptoms -- Chapter 6. Pre-clinical rodent models of pain 
       for genomics studies -- Chapter 7. Clinical models of 
       experimental pain for genomics studies -- Chapter 8. 
       Clinical pain genomics research -- Chapter 9. Pain 
       phenotyping (methods, measures) -- Chapter 10. Precision 
       health and pain genomics -- Chapter 11. Exemplars of pain 
       genomics studies (could be multiple chapters) -- Chapter 
       12. Roadmap to translation of pain genomics 
520    This book provides an overview of the field of pain 
       genomics and the genomics of related, or co-occuring, 
       symptoms, the current state-of-the-science, and challenges
       that remain. It brings differing views in the field 
       together and provides examples of translational science 
       from using cellular and rodent models to human clinical 
       trials. This book's structure leads the reader through the
       physiology of pain and genomics into how pain is studied, 
       mechanisms of acute and chronic pain, various protocols 
       that are used throughout the field along with the pros/
       cons of the current methods used, and project into the 
       future of pain genomics. This work is intended for 
       classroom teaching, for nurses, for novice researchers in 
       symptom science and pain research as well as students and 
       postdoctoral fellows 
650  0 Pain|xGenetic aspects 
650  0 Genomics 
650 14 Nursing Research 
650 24 Genetics and Genomics 
650 24 Pain Medicine 
700 1  Dorsey, Susan G.,|eeditor 
700 1  Starkweather, Angela R.,|eeditor 
710 2  SpringerLink (Online service) 
773 0  |tSpringer eBooks 
856 40 |uhttps://doi.org/10.1007/978-3-030-21657-3