Record:   Prev Next
Author Starkstein, Sergio E
Title Psychiatric and Cognitive Disorders in Parkinson's Disease
Imprint Cambridge : Cambridge University Press, 2002
©2002
book jacket
Descript 1 online resource (241 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Note Cover -- Half-title -- Title -- Copyright -- Dedication -- Contents -- Preface -- 1 Introduction -- 2 Epidemiologic, clinical, and therapeutic aspects of Parkinson's disease -- Introduction -- Clinical vignette -- Phenomenology of PD -- Staging of illness -- Clinical features -- Resting tremor -- Rigidity -- Bradykinesia -- Postural instability -- Autonomic dysfunction -- Orthostasis -- Dementia -- Depression -- Psychotic features -- Clusters of parkinsonian signs and subgroups of the disease -- Motor fluctuations -- Motor fluctuations related to l-dopa -- Types of motor fluctuations -- Stable motor response -- Wearing-off -- On-off phenomenon -- Dyskinesias -- Prevalence and etiology of PD -- Neuroimaging correlates of PD -- Neuropathologic correlates of PD -- Mechanisms of PD -- The basal ganglia system -- Pharmacology of dopamine receptors -- Neurochemical mechanism -- Treatment of PD -- Neuroprotective agents -- Anticholinergics -- N-methyl-D-aspartate (NMDA) blockers -- L-dopa -- Dopamine agonists -- Bromocriptine mesylate -- Lisuride hydrogen maleate -- Pergolide mesylate -- Apomorphine -- Cabergoline -- Ropinirole -- Pramipexole -- Catechol-O-methyl-transferase (COMT) inhibitors -- Treatment of dyskinesias and motor fluctuations -- Surgical treatment -- Globus Pallidus -- Thalamus -- Subthalamic nucleus -- General conclusions -- 3 Parkinsonism and Parkinson's disease -- Progressive supranuclear palsy -- Clinical vignette -- Clinical aspects -- Laboratory findings -- Neuropathologic findings -- Multisystem atrophy -- Clinical vignette -- Clinical aspects -- Laboratory findings -- Neuropathologic findings -- Dementia with Lewy bodies -- Clinical vignette -- Clinical aspects -- Laboratory findings -- Neuropathologic findings -- Secondary parkinsonism -- Drug-induced parkinsonism -- Clinical vignette -- Toxic and mood-related parkinsonism
Clinical vignette -- Vascular parkinsonism -- Clinical vignette -- Corticobasal ganglionic degeneration -- Clinical vignette -- Clinical aspects -- Laboratory studies -- Neuropathology -- Alzheimer's disease -- Clinical vignette -- General conclusions -- 4 Cognitive deficits in Parkinson's disease -- Dementia in PD -- Clinical vignette -- Diagnosis of dementia -- Prevalence of dementia -- Phenomenology of dementia -- Cognitive differences between cortical and subcortical dementias -- Emotional differences between cortical and subcortical dementias -- Motor differences in cortical and subcortical dementias -- Neuroimaging differences between cortical and subcortical dementias -- Clinical correlates of dementia -- Specific cognitive deficits in PD -- Executive functions -- Visuospatial deficits -- Speech and language -- Bradyphrenia -- Event-related potentials as a measure of bradyphrenia -- Attention and memory deficits -- Mechanisms of dementia and cognitive deficits in PD -- Coexisting AD pathology -- Cortical Lewy bodies -- Depletion of dopaminergic neurons -- Depletion of other neurotransmitter systems -- Other mechanisms of dementia -- Mechanisms of specific cognitive deficits -- General conclusions -- 5 Depression in Parkinson's disease -- Clinical vignette -- Phenomenologic aspects of depression in PD -- Prevalence of depression in PD -- The course of depression in PD -- Physical disability and depression in PD -- Cognitive impairments and depression in PD -- Other correlates of depression in PD -- Biological markers of depression in PD -- Mechanisms of depression in PD -- General conclusions -- 6 Anxiety, phobias, apathy, and premorbid personality in Parkinson's disease -- Premorbid personality in PD -- Mechanism of personality changes -- Anxiety in PD -- Anxiety and motor fluctuations -- Mechanism of anxiety -- Panic disorder in PD
Clinical vignette -- Apathy in PD -- General conclusions -- 7 Neuropsychologic and psychiatric side-effects of antiparkinsonian medication -- Introduction -- Clinical vignette -- Psychosis in PD -- Phenomenology of psychosis -- Delusions -- Illusions -- Delirium -- Hallucinations -- Vivid dreams -- Prevalence and clinical correlates of psychosis -- Mechanism of psychosis -- Neuropsychologic and psychiatric effects of specific antiparkinsonian medications in PD -- L-dopa -- Dopaminergic agonists -- Apomorphine -- Amantadine hydrochloride -- Selegiline hydrochloride -- Anticholinergic drugs -- General conclusions -- 8 Treatment of psychiatric disorders in Parkinson's disease -- Treatment of depression in PD -- Antidepressant drugs -- Tricyclic antidepressants -- Monoamine-oxidase inhibitors -- Selective serotonergic reuptake inhibitors -- Other antidepressants -- Electroconvulsive therapy -- Psychotherapy -- Treatment of psychosis in PD -- Clozapine -- Risperidone -- Olanzapine -- Other antipsychotics -- Other treatments for psychosis -- General conclusions -- Appendix: scales for clinical assessment -- A.1 Unified Parkinson's disease rating scale (UPDRS) (adapted from Langston et al.,1992) -- I. Mentation, behavior, mood -- II. Activities of daily living (specify for ''On/Off'') -- III. Motor examination -- IV.Complications of therapy (during the previous week) -- DYSKINESIAS -- CLINICAL FLUCTUATIONS -- OTHER COMPLICATIONS -- A.2 Dyskinesia rating scale (adapted from Goetz et al., 1994) -- A.3 Schwab and England rating scale (adapted from Lang, 1990) -- A.4 Webster rating scale for parkinsonism (adapted from Webster, 1968) -- A.5 Parkinson psychosis rating scale (PPRS) (adapted from Friedberg et al., 1998) -- A.6 Apathy rating scale (adapted from Starkstein et al., 1995) -- A.7 EUROQOL rating scale (adapted from Schrag et al., 2000) -- References
Chapter 2 -- Chapter 3 -- Chapter 4 -- Chapter 5 -- Chapter 6 -- Chapter 7 -- Chapter 8 -- Appendix -- Index
A clear, comprehensive and practical account of the emotional and cognitive aspects of Parkinson's disease
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Link Print version: Starkstein, Sergio E. Psychiatric and Cognitive Disorders in Parkinson's Disease Cambridge : Cambridge University Press,c2002 9780521663052
Subject Parkinson's disease--Patients--Mental health
Electronic books
Alt Author Merello, Marcelo
Record:   Prev Next