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Author Khademhosseini, Ali
Title Micro and Nanoengineering of the Cell Microenvironment : Technologies and Applications
Imprint Norwood : Artech House, 2008
©2008
book jacket
Descript 1 online resource (646 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Note Micro and Nanoengineering of the Cell Microenvironment: Technologies and Applications -- Contents -- Foreword -- Chapter 1 Micro- and Nanoengineering the Cellular Microenvironment -- 1.1 Introduction -- 1.2 Cellular Microenvironment -- 1.3 Controlling Cellular Behavior -- 1.4 Micro- and Nanoengineering the Cellular Microenvironment -- 1.5 Book Structure -- References -- Chapter 2 Gradient-Generating Microfluidic Devices for Cell Biology Research -- 2.1 Introduction -- 2.2 Conventional Devices for Soluble Gradient Generation -- 2.3 Microfluidic-Based Devices for Gradient Generation -- 2.4 Biological Applications of Gradient-Generating Microfluidic Devices -- 2.5 Summary and Future Directions -- References -- Chapter 3 Surface Patterning for Controlling Cell-Substrate Interactions -- 3.1 Introduction -- 3.2 Self-Assembled Monolayers, Lithography, and Other Important Tools -- 3.3 Controlling the Adsorption of Proteins on Surface -- 3.4 Patterning of Proteins and Cells -- 3.5 Dynamic Patterning of Cells -- 3.6 Other Systems for Patterning Cells -- 3.7 Conclusion -- References -- Chapter 4 Patterned Cocultures for Controlling Cell-Cell Interactions -- 4.1 Introduction -- 4.2 Random Coculture Systems -- 4.3 Patterned Coculture Systems -- 4.4 Conclusion -- References -- Chapter 5 Micro- and Nanofabricated Scaffolds for Three-Dimensional Tissue Recapitulation -- 5.1 Introduction -- 5.2 Microfabricated Interfaces -- 5.3 Nanofabricated Interfaces -- 5.4 Conclusion -- References -- Chapter 6 Biomimetic Hydrogels to Support and Guide Tissue Formation -- 6.1 Introduction -- 6.2 Hydrogels and Their Synthesis -- 6.3 Incorporating Bioactive Factors into Hydrogels -- 6.4 Two-Dimensional Patterning of Hydrogels -- 6.5 Three-Dimensional Rapid Prototyping of Hydrogels -- 6.6 Summary -- References
Chapter 7 Three-Dimensional Cell-Printing Technologies for Tissue Engineering -- 7.1 Overview -- 7.2 Development of Cell-Printing Technologies -- 7.3 Conventional Three-Dimensional Cell-Printing Methods -- 7.4 Current Applications of Cell-Printing Technology: Organ Printing -- 7.5 Other Applications of Cell Printing -- 7.6 Technologies for Three-Dimensional Cell Printing: Single Cell Epitaxy by Acoustic Picoliter Droplets -- 7.7 Conclusion -- References -- Chapter 8 Using Microfabrication to Engineer Cellular and Multicellular Architecture -- 8.1 Introduction -- 8.2 Patterning Adhesion -- 8.3 Patterning Single Cells -- 8.4 Multicellular Patterning -- 8.5 Engineering Single Cell-Cell Interactions -- 8.6 Cell Patterning by Active Positioning: Dielectrophoresis and Microfluidics -- 8.7 Three-Dimensional Patterning -- 8.8 Future Directions -- References -- Chapter 9 Technologies and Applications for Engineering Substrate Mechanics to Regulate Cell Response -- 9.1 Introduction -- 9.2 How Cells Sense the Stiffness of Their Substrate -- 9.3 Technologies to Engineer the Mechanical Properties of the Substrate -- 9.4 Effects of Substrate Mechanics on Cell Response -- 9.5 Summary and Future Challenges -- References -- Chapter 10 Engineered Surface Nanotopography for Controlling Cell-Substrate Interactions -- 10.1 Introduction -- 10.2 Methods for Generating Nanotopography -- 10.3 Topical Issues in Controlling Cell-Substrate Interactions -- 10.4 Conclusion -- References -- Chapter 11 Microfluidics for Assisted Reproductive Technologies -- 11.1 Introduction -- 11.2 Micro-/Nanotechnology -- 11.3 Conclusions and Future Directions -- References -- Chapter 12 Microscale Technologies for Engineering Embryonic Stem Cell Environments -- 12.1 Embryonic Stem Cells -- 12.2 Microscale Technologies -- 12.3 Conclusion -- References
Chapter 13 Neuroscience on a Chip: Microfabrication for In Vitro Neurobiology -- 13.1 Introduction -- 13.2 Microengineered Neurite Growth and Neuronal Polarity -- 13.3 Microengineered Cell-Cell Signaling -- 13.4 Conclusions and Future Directions -- References -- Chapter 14 Self-Assembly of Nanomaterials for Engineering Cell Microenvironment -- 14.1 Overview -- 14.2 Proteins and Peptides -- 14.3 Self-Assembly of Proteins and Peptides -- 14.4 Findings About Amphiphilic and Surfactantlike Peptides -- 14.5 Findings About Three-Dimensional Peptide Matrix Scaffolds -- 14.6 Use of Peptide Hydogels in Regenerative Biology and Three-Dimensional Cell Culture -- 14.7 Applications of Synthetic Amphiphilic Peptides in Other Fields of Nanotechnology -- 14.8 Conclusion -- References -- Chapter 15 Microvascular Engineering: Design, Modeling, and Microfabrication -- 15.1 Introduction -- 15.2 Design of Microvascular Networks -- 15.3 Computational Models for Microvascular Networks -- 15.4 Microfabrication Technology for Vascular Network Formation -- 15.5 Conclusion -- References -- Chapter 16 Nanotechnology for Inducing Angiogenesis -- 16.1 Introduction -- 16.2 Nanostructured Scaffolds and Angiogenesis -- 16.3 Functionalized Smooth Surfaces and Angiogenesis -- 16.4 Conclusion -- References -- Chapter 17 Micropatterning Approaches for Cardiac Biology -- 17.1 Introduction -- 17.2 Isolation and Culture of Cardiac Myocytes -- 17.3 Engineering the Cellular Microenvironment In Vitro -- 17.4 Traction Force Microscopy for Cardiac Myocytes -- 17.5 Conclusions and Future Perspectives -- References -- Chapter 18 Microreactors for Cardiac Tissue Engineering -- 18.1 Introduction -- 18.2 Patterned Cardiomyocyte Cultures in Two Dimensions -- 18.3 Patterned Cardiomyocyte Cultures in Three Dimensions -- 18.4 Microsystems for Co- and Tricultures in Two and Three Dimensions
18.5 Microbioreactors for Culture of Cardiac Organoids -- 18.6 Microfluidic Devices for Cardiac Cell Separation -- 18.7 Looking Forward -- 18.8 Conclusion -- References -- Chapter 19 Nanoengineered Hydrogels for Stem Cell Cartilage Tissue Engineering -- 19.1 Hydrogel Microenvironments -- 19.2 Stem Cell Encapsulation in Hydrogels -- 19.3 Coculture Microenvironments for Directing Stem CellDifferentiation and Tissue Development -- References -- Chapter 20 Microscale Approaches for Bone Tissue Engineering -- 20.1 Introduction -- 20.2 Importance of Cell-Cell Interactions for Regulating Osteogenesis -- 20.3 Use of Substrate Properties to Control Osteogenesis -- 20.4 Techniques for Translating Two-Dimensional Systems to Three-Dimensional Scaffolds -- 20.5 Conclusion -- References -- Chapter 21 Nanoengineering for Bone Tissue Engineering -- 21.1 Introduction -- 21.2 The Role of Nanomaterials in Orthopedic Implants -- 21.3 Future Challenges -- References -- Chapter 22 Bioinspired Engineered Nanocomposites for Bone Tissue Engineering -- 22.1 Introduction -- 22.2 Bone Structure -- 22.3 Degradable Polymers as Scaffolds for Bone Regeneration -- 22.4 Degradable Composite Scaffolds for Bone Regeneration -- 22.5 Collagen nanostructure and its effect on differentiation of bone marrow stromal cells -- 22.6 Biomimetic Hydrogel Nanocomposites for Bone Regeneration -- 22.7 Conclusion -- References -- Chapter 23 Technological Approaches to Renal Replacement Therapies -- 23.1 Introduction -- 23.2 Kidney Functioning Overview -- 23.3 Kidney Failure -- 23.4 Treatments -- 23.5 History of Hemodialysis -- 23.6 Dialyzer Improvements -- 23.7 Innovative Hemodialysis Approaches -- 23.8 Conclusion -- References -- Chapter 24 Engineering Pulmonary Epithelia and Their Mechanical Microenvironments -- 24.1 Introduction -- 24.2 The Lung and Pulmonary Epithelial Cells
24.3 In Vitro Production and Engineering of Pulmonary Epithelium -- 24.4 Engineering of Cell-Matrix and Cell-Cell Interactions -- 24.5 Engineering of Cell-Fluid Interactions -- 24.6 Measurements of Mechanically Induced Inflammatory Responses -- 24.7 Conclusion -- References -- Chapter 25 Microfabricated Systems for Analyzing Immune-Cell Functions -- 25.1 Introduction -- 25.2 Micro- and Nanopatterned Surfaces as Tools to Dissect Immune-Cell Functions -- 25.3 Single-Cell Microarrays: Microwells and Microchambers fo rAssaying the Functions of Individual Lymphocytes -- 25.4 Control of Immune-Cell Migration in Model Microenvironments -- 25.5 Conclusions and Outlook -- References -- Chapter 26 Microscale Hepatic Tissue Engineering -- 26.1 Introduction -- 26.2 Strategies for Developing Stable Hepatocyte Culture Models -- 26.3 Bioartificial Liver Devices -- 26.4 Hepatic Constructs for Transplantation -- 26.5 Liver-Cell Microarrays -- 26.6 Summary -- References -- Chapter 27 Nano- and Microtechnologies for the Development of Engineered Skin Substitutes -- 27.1 Overview -- 27.2 Nano- and Microscale Approaches to Producing Engineered Skin Substitutes -- 27.3 Nano- and Microscale Approaches for Controlling Cellular Microenvironments -- 27.4 Future Considerations -- References -- About the Editors -- List of Contributors -- Index
Supported with 140 illustrations, the volume exhaustively covers the micro- and nano-system technologies involved in developing cell-based bioengineering applications. You get full details on efforts to engineer the soluble and insoluble cell microenvironments, including the latest advances in microfluidic devices, surface patterning, 3D scaffolds, and techniques for engineering cellular mechanical properties and topography
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Link Print version: Khademhosseini, Ali Micro and Nanoengineering of the Cell Microenvironment : Technologies and Applications Norwood : Artech House,c2008 9781596931480
Subject Biomedical engineering.;Cells -- Microbiology.;Ultrastructure (Biology)
Electronic books
Alt Author Borenstein, Jeffrey
Toner, Mehmet
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