LEADER 00000nam a22004813i 4500 
001    EBC456882 
003    MiAaPQ 
005    20200713055135.0 
006    m     o  d |       
007    cr cnu|||||||| 
008    200713s2008    xx      o     ||||0 eng d 
020    9781596931497|q(electronic bk.) 
020    |z9781596931480 
035    (MiAaPQ)EBC456882 
035    (Au-PeEL)EBL456882 
035    (CaPaEBR)ebr10312947 
035    (OCoLC)935270505 
040    MiAaPQ|beng|erda|epn|cMiAaPQ|dMiAaPQ 
050  4 QH611 -- .M537 2008eb 
082 0  571.6;610.28 
100 1  Khademhosseini, Ali 
245 10 Micro and Nanoengineering of the Cell Microenvironment :
       |bTechnologies and Applications 
264  1 Norwood :|bArtech House,|c2008 
264  4 |c©2008 
300    1 online resource (646 pages) 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
505 0  Micro and Nanoengineering of the Cell Microenvironment: 
       Technologies and Applications -- Contents -- Foreword -- 
       Chapter 1 Micro- and Nanoengineering the Cellular 
       Microenvironment -- 1.1 Introduction -- 1.2 Cellular 
       Microenvironment -- 1.3 Controlling Cellular Behavior -- 
       1.4 Micro- and Nanoengineering the Cellular 
       Microenvironment -- 1.5 Book Structure -- References -- 
       Chapter 2 Gradient-Generating Microfluidic Devices for 
       Cell Biology Research -- 2.1 Introduction -- 2.2 
       Conventional Devices for Soluble Gradient Generation -- 
       2.3 Microfluidic-Based Devices for Gradient Generation -- 
       2.4 Biological Applications of Gradient-Generating 
       Microfluidic Devices -- 2.5 Summary and Future Directions 
       -- References -- Chapter 3 Surface Patterning for 
       Controlling Cell-Substrate Interactions -- 3.1 
       Introduction -- 3.2 Self-Assembled Monolayers, Lithography,
       and Other Important Tools -- 3.3 Controlling the 
       Adsorption of Proteins on Surface -- 3.4 Patterning of 
       Proteins and Cells -- 3.5 Dynamic Patterning of Cells -- 
       3.6 Other Systems for Patterning Cells -- 3.7 Conclusion -
       - References -- Chapter 4 Patterned Cocultures for 
       Controlling Cell-Cell Interactions -- 4.1 Introduction -- 
       4.2 Random Coculture Systems -- 4.3 Patterned Coculture 
       Systems -- 4.4 Conclusion -- References -- Chapter 5 Micro
       - and Nanofabricated Scaffolds for Three-Dimensional 
       Tissue Recapitulation -- 5.1 Introduction -- 5.2 
       Microfabricated Interfaces -- 5.3 Nanofabricated 
       Interfaces -- 5.4 Conclusion -- References -- Chapter 6 
       Biomimetic Hydrogels to Support and Guide Tissue Formation
       -- 6.1 Introduction -- 6.2 Hydrogels and Their Synthesis -
       - 6.3 Incorporating Bioactive Factors into Hydrogels -- 
       6.4 Two-Dimensional Patterning of Hydrogels -- 6.5 Three-
       Dimensional Rapid Prototyping of Hydrogels -- 6.6 Summary 
       -- References 
505 8  Chapter 7 Three-Dimensional Cell-Printing Technologies for
       Tissue Engineering -- 7.1 Overview -- 7.2 Development of 
       Cell-Printing Technologies -- 7.3 Conventional Three-
       Dimensional Cell-Printing Methods -- 7.4 Current 
       Applications of Cell-Printing Technology: Organ Printing -
       - 7.5 Other Applications of Cell Printing -- 7.6 
       Technologies for Three-Dimensional Cell Printing: Single 
       Cell Epitaxy by Acoustic Picoliter Droplets -- 7.7 
       Conclusion -- References -- Chapter 8 Using 
       Microfabrication to Engineer Cellular and Multicellular 
       Architecture -- 8.1 Introduction -- 8.2 Patterning 
       Adhesion -- 8.3 Patterning Single Cells -- 8.4 
       Multicellular Patterning -- 8.5 Engineering Single Cell-
       Cell Interactions -- 8.6 Cell Patterning by Active 
       Positioning: Dielectrophoresis and Microfluidics -- 8.7 
       Three-Dimensional Patterning -- 8.8 Future Directions -- 
       References -- Chapter 9 Technologies and Applications for 
       Engineering Substrate Mechanics to Regulate Cell Response 
       -- 9.1 Introduction -- 9.2 How Cells Sense the Stiffness 
       of Their Substrate -- 9.3 Technologies to Engineer the 
       Mechanical Properties of the Substrate -- 9.4 Effects of 
       Substrate Mechanics on Cell Response -- 9.5 Summary and 
       Future Challenges -- References -- Chapter 10 Engineered 
       Surface Nanotopography for Controlling Cell-Substrate 
       Interactions -- 10.1 Introduction -- 10.2 Methods for 
       Generating Nanotopography -- 10.3 Topical Issues in 
       Controlling Cell-Substrate Interactions -- 10.4 Conclusion
       -- References -- Chapter 11 Microfluidics for Assisted 
       Reproductive Technologies -- 11.1 Introduction -- 11.2 
       Micro-/Nanotechnology -- 11.3 Conclusions and Future 
       Directions -- References -- Chapter 12 Microscale 
       Technologies for Engineering Embryonic Stem Cell 
       Environments -- 12.1 Embryonic Stem Cells -- 12.2 
       Microscale Technologies -- 12.3 Conclusion -- References 
505 8  Chapter 13 Neuroscience on a Chip: Microfabrication for In
       Vitro Neurobiology -- 13.1 Introduction -- 13.2 
       Microengineered Neurite Growth and Neuronal Polarity -- 
       13.3 Microengineered Cell-Cell Signaling -- 13.4 
       Conclusions and Future Directions -- References -- Chapter
       14 Self-Assembly of Nanomaterials for Engineering Cell 
       Microenvironment -- 14.1 Overview -- 14.2 Proteins and 
       Peptides -- 14.3 Self-Assembly of Proteins and Peptides --
       14.4 Findings About Amphiphilic and Surfactantlike 
       Peptides -- 14.5 Findings About Three-Dimensional Peptide 
       Matrix Scaffolds -- 14.6 Use of Peptide Hydogels in 
       Regenerative Biology and Three-Dimensional Cell Culture --
       14.7 Applications of Synthetic Amphiphilic Peptides in 
       Other Fields of Nanotechnology -- 14.8 Conclusion -- 
       References -- Chapter 15 Microvascular Engineering: Design,
       Modeling, and Microfabrication -- 15.1 Introduction -- 
       15.2 Design of Microvascular Networks -- 15.3 
       Computational Models for Microvascular Networks -- 15.4 
       Microfabrication Technology for Vascular Network Formation
       -- 15.5 Conclusion -- References -- Chapter 16 
       Nanotechnology for Inducing Angiogenesis -- 16.1 
       Introduction -- 16.2 Nanostructured Scaffolds and 
       Angiogenesis -- 16.3 Functionalized Smooth Surfaces and 
       Angiogenesis -- 16.4 Conclusion -- References -- Chapter 
       17 Micropatterning Approaches for Cardiac Biology -- 17.1 
       Introduction -- 17.2 Isolation and Culture of Cardiac 
       Myocytes -- 17.3 Engineering the Cellular Microenvironment
       In Vitro -- 17.4 Traction Force Microscopy for Cardiac 
       Myocytes -- 17.5 Conclusions and Future Perspectives -- 
       References -- Chapter 18 Microreactors for Cardiac Tissue 
       Engineering -- 18.1 Introduction -- 18.2 Patterned 
       Cardiomyocyte Cultures in Two Dimensions -- 18.3 Patterned
       Cardiomyocyte Cultures in Three Dimensions -- 18.4 
       Microsystems for Co- and Tricultures in Two and Three 
       Dimensions 
505 8  18.5 Microbioreactors for Culture of Cardiac Organoids -- 
       18.6 Microfluidic Devices for Cardiac Cell Separation -- 
       18.7 Looking Forward -- 18.8 Conclusion -- References -- 
       Chapter 19 Nanoengineered Hydrogels for Stem Cell 
       Cartilage Tissue Engineering -- 19.1 Hydrogel 
       Microenvironments -- 19.2 Stem Cell Encapsulation in 
       Hydrogels -- 19.3 Coculture Microenvironments for 
       Directing Stem CellDifferentiation and Tissue Development 
       -- References -- Chapter 20 Microscale Approaches for Bone
       Tissue Engineering -- 20.1 Introduction -- 20.2 Importance
       of Cell-Cell Interactions for Regulating Osteogenesis -- 
       20.3 Use of Substrate Properties to Control Osteogenesis -
       - 20.4 Techniques for Translating Two-Dimensional Systems 
       to Three-Dimensional Scaffolds -- 20.5 Conclusion -- 
       References -- Chapter 21 Nanoengineering for Bone Tissue 
       Engineering -- 21.1 Introduction -- 21.2 The Role of 
       Nanomaterials in Orthopedic Implants -- 21.3 Future 
       Challenges -- References -- Chapter 22 Bioinspired 
       Engineered Nanocomposites for Bone Tissue Engineering -- 
       22.1 Introduction -- 22.2 Bone Structure -- 22.3 
       Degradable Polymers as Scaffolds for Bone Regeneration -- 
       22.4 Degradable Composite Scaffolds for Bone Regeneration 
       -- 22.5 Collagen nanostructure and its effect on 
       differentiation of bone marrow stromal cells -- 22.6 
       Biomimetic Hydrogel Nanocomposites for Bone Regeneration -
       - 22.7 Conclusion -- References -- Chapter 23 
       Technological Approaches to Renal Replacement Therapies --
       23.1 Introduction -- 23.2 Kidney Functioning Overview -- 
       23.3 Kidney Failure -- 23.4 Treatments -- 23.5 History of 
       Hemodialysis -- 23.6 Dialyzer Improvements -- 23.7 
       Innovative Hemodialysis Approaches -- 23.8 Conclusion -- 
       References -- Chapter 24 Engineering Pulmonary Epithelia 
       and Their Mechanical Microenvironments -- 24.1 
       Introduction -- 24.2 The Lung and Pulmonary Epithelial 
       Cells 
505 8  24.3 In Vitro Production and Engineering of Pulmonary 
       Epithelium -- 24.4 Engineering of Cell-Matrix and Cell-
       Cell Interactions -- 24.5 Engineering of Cell-Fluid 
       Interactions -- 24.6 Measurements of Mechanically Induced 
       Inflammatory Responses -- 24.7 Conclusion -- References --
       Chapter 25 Microfabricated Systems for Analyzing Immune-
       Cell Functions -- 25.1 Introduction -- 25.2 Micro- and 
       Nanopatterned Surfaces as Tools to Dissect Immune-Cell 
       Functions -- 25.3 Single-Cell Microarrays: Microwells and 
       Microchambers fo rAssaying the Functions of Individual 
       Lymphocytes -- 25.4 Control of Immune-Cell Migration in 
       Model Microenvironments -- 25.5 Conclusions and Outlook --
       References -- Chapter 26 Microscale Hepatic Tissue 
       Engineering -- 26.1 Introduction -- 26.2 Strategies for 
       Developing Stable Hepatocyte Culture Models -- 26.3 
       Bioartificial Liver Devices -- 26.4 Hepatic Constructs for
       Transplantation -- 26.5 Liver-Cell Microarrays -- 26.6 
       Summary -- References -- Chapter 27 Nano- and 
       Microtechnologies for the Development of Engineered Skin 
       Substitutes -- 27.1 Overview -- 27.2 Nano- and Microscale 
       Approaches to Producing Engineered Skin Substitutes -- 
       27.3 Nano- and Microscale Approaches for Controlling 
       Cellular Microenvironments -- 27.4 Future Considerations -
       - References -- About the Editors -- List of Contributors 
       -- Index 
520    Supported with 140 illustrations, the volume exhaustively 
       covers the micro- and nano-system technologies involved in
       developing cell-based bioengineering applications. You get
       full details on efforts to engineer the soluble and 
       insoluble cell microenvironments, including the latest 
       advances in microfluidic devices, surface patterning, 3D 
       scaffolds, and techniques for engineering cellular 
       mechanical properties and topography 
588    Description based on publisher supplied metadata and other
       sources 
590    Electronic reproduction. Ann Arbor, Michigan : ProQuest 
       Ebook Central, 2020. Available via World Wide Web. Access 
       may be limited to ProQuest Ebook Central affiliated 
       libraries 
650  0 Biomedical engineering.;Cells -- 
       Microbiology.;Ultrastructure (Biology) 
655  4 Electronic books 
700 1  Borenstein, Jeffrey 
700 1  Toner, Mehmet 
776 08 |iPrint version:|aKhademhosseini, Ali|tMicro and 
       Nanoengineering of the Cell Microenvironment : 
       Technologies and Applications|dNorwood : Artech House,
       c2008|z9781596931480 
856 40 |uhttps://ebookcentral.proquest.com/lib/sinciatw/
       detail.action?docID=456882|zClick to View