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Author Bagchi, Debasis
Title Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome
Imprint San Diego : Elsevier Science & Technology, 2012
©2012
book jacket
Descript 1 online resource (553 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Note Front Cover -- Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome -- Copyright -- Dedication -- Contents -- Preface -- Contributors -- SECTION I - EPIDEMIOLOGY AND OVERVIEW -- Chapter 1 - Type 1 Diabetes Mellitus: An Overview -- INTRODUCTION -- DEFINITION -- EPIDEMIOLOGY -- PATHOPHYSIOLOGY -- DIAGNOSIS -- CLINICAL PRESENTATION -- MANAGEMENT -- COMORBIDITIES -- COMPLICATIONS -- PREVENTION AND INTERVENTION TRIALS -- References -- Chapter 2 - Overview of Type 2 Diabetes -- DEFINITION AND DIAGNOSTIC CRITERIA -- EPIDEMIOLOGY OF TYPE 2 DIABETES AND ITS COMPLICATIONS -- GENETIC RISK FACTORS FOR TYPE 2 DIABETES -- RISK FACTORS AND SCREENING FOR TYPE 2 DIABETES -- DIABETES IN PREGNANCY: IMPLICATIONS FOR MOTHER AND OFFSPRING -- EVIDENCE FOR METABOLIC PROGRAMMING OF DIABETES IN EARLY LIFE -- EARLY INTERVENTION IN TYPE 2 DIABETES -- CLINICAL MANAGEMENT OF TYPE 2 DIABETES -- TREATMENT GUIDELINES -- NUTRITION AND LIFESTYLE INTERVENTION -- PHARMACOLOGICAL TREATMENTS -- BARIATRIC SURGERY -- ECONOMIC IMPACT OF TYPE 2 DIABETES -- FUTURE DIRECTIONS -- References -- Chapter 3 - Pathogenesis of Type 2 Diabetes-A Comprehensive Analysis -- INTRODUCTION -- GENETICS OF TYPE 2 DIABETES -- MAINTENANCE OF NORMAL GLUCOSE HOMEOSTASIS -- IMPAIRED GLUCOSE HOMEOSTASIS IN PATIENTS WITH TYPE 2 DIABETES -- MECHANISTIC ACTIONS WHICH LEAD TO PROGRESSIVE β-CELL FAILURE AND TYPE 2 DIABETES -- SUMMARY -- References -- Chapter 4 - Managing the Broad Spectrum of Type 2 Diabetes -- INTRODUCTION -- EVOLVING PATHOPHYSIOLOGY OF TYPE 2 DIABETES -- ALTERING THE PROGRESSION OF TYPE 2 DIABETES -- NEED FOR EARLY INTERVENTION -- AGGRESSIVE MANAGEMENT AFTER DIAGNOSIS -- HOW LOW DO WE GO FOR GLYCEMIC CONTROL? -- TREATMENT OPTIONS -- SELF-MANAGEMENT EDUCATION -- LIFESTYLE MODIFICATION -- MEAL PLANNING -- PHYSICAL ACTIVITY -- PHARMACOLOGICAL TREATMENT
WHEN TO ADJUST TREATMENT -- INITIATING INSULIN THERAPY -- INSULIN DELIVERY DEVICES -- CONCLUSIONS -- References -- Chapter 5 - Prediabetes: Prevalence, Pathogenesis, and Recognition of Enhanced Risk -- BACKGROUND -- PREVALENCE -- RESULTS -- PATHOGENESIS -- RECOGNITION OF ENHANCED RISK -- MEANS FOR CARDIOMETABOLIC RISK FACTORS -- DISCUSSION -- CONCLUSION -- References -- Chapter 6 - Obesity and Type 2 Diabetes in Youths: New Challenges to Overcome -- OBESITY: THE 21ST CENTURY EPIDEMIC -- METABOLIC COMPLICATIONS OF OBESITY IN CHILDREN AND ADOLESCENTS -- TYPE 2 DIABETES IN CHILDREN AND ADOLESCENCE: A NEW FRIGHTENING EPIDEMIC? -- PATHOGENESIS OF TYPE 2 DIABETES IN OBESE CHILDREN AND ADOLESCENTS -- ROLE OF ECTOPIC FAT DEPOSITION IN THE PATHOGENESIS OF INSULIN RESISTANCE -- THE β-CELL IN THE STORM OF INSULIN RESISTANCE -- THERAPY OF TYPE 2 DIABETES IN YOUTHS -- CONCLUSIONS AND FUTURE PERSPECTIVES -- References -- Chapter 7 - Diabetes Pathophysiology: A Nutritional Perspective -- INTRODUCTION -- DIETARY TREATMENT FOR DIABETES AT THE TURN OF THE 20TH CENTURY -- DIETARY RECOMMENDATIONS -- GLUCOSE CONTROL -- LOW-CARBOHYDRATE DIETS -- CONCLUSIONS -- References -- Chapter 8 - Diabetes Mellitus: A Nursing Perspective -- INTRODUCTION/OVERVIEW -- NURSING PERSPECTIVE -- PREVENTION AND MANAGEMENT OF DIABETES BY NURSING PROFESSIONALS -- RESEARCH -- CONCLUSION -- References -- Chapter 9 - Roles of Environmental Pollution and Pesticides in Metabolic Syndrome and Diabetes: The Epidemiological Evidence -- INTRODUCTION -- DIOXINS, FURANS AND POLYCHLORINATED BIPHENYLS -- PESTICIDES -- BISPHENOL-A -- AIR POLLUTION -- TOXIC METALS -- SUMMARY AND FUTURE RESEARCH -- References -- Chapter 10 - Preventing Diabetes with Diet and Exercise -- INTRODUCTION -- DIET AND EXERCISE INTERVENTIONS TO PREVENT DIABETES -- WEIGHT LOSS AND EXERCISE BOTH CONTRIBUTE TO REDUCING DIABETES RISK
WHAT TYPE OF DIET BEST ENCOURAGES WEIGHT LOSS? -- THE ROLE OF EXERCISE -- CONCLUSION -- References -- SECTION II - TYPES OF DIABETES AND ITS CORRELATION WITH OTHER DISEASES -- Chapter 11 - The Role of Insulin Resistance in the Cardiorenal Syndrome -- INTRODUCTION -- EPIDEMIOLOGIC EVIDENCE -- PATHOPHYSIOLOGIC LINKS BETWEEN INSULIN RESISTANCE, OBESITY, AND THE CARDIORENAL SYNDROME -- MICROALBUMINURIA IN THE CARDIORENAL SYNDROME -- INSULIN RESISTANCE IN THE CARDIORENAL SYNDROME -- OXIDATIVE STRESS AND ENDOPLASMIC STRESS IN THE CARDIORENAL SYNDROME -- INAPPROPRIATE ACTIVATION OF THE RAAS -- CONCLUSIONS AND PERSPECTIVES -- References -- Chapter 12 - An Overview of Diabetic Nephropathy -- INTRODUCTION -- CLINICAL FEATURES OF DIABETIC NEPHROPATHY -- INVOLVEMENT OF METABOLIC FACTORS IN DIABETIC NEPHROPATHY -- ROLE OF RAS IN DIABETIC NEPHROPATHY -- CONCLUSION -- References -- Chapter 13 - An Overview of Diabetes and Ocular Health -- INTRODUCTION -- EPIDEMIOLOGY/RISK FACTORS -- PATHOPHYSIOLOGY -- CLINICAL ASSESSMENT -- THERAPY -- CONCLUSIONS -- References -- Chapter 14 - An Overview of Diabetic Retinopathy -- INTRODUCTION -- EPIDEMIOLOGY -- CLASSIFICATION -- RANDOMIZED CLINICAL TRIALS -- TREATMENT GUIDELINES -- References -- Chapter 15 - Role of Peripheral Neuropathy in the Development of Foot Ulceration and Impaired Wound Healing in Diabetes Mellitus -- INTRODUCTION -- DIABETIC NEUROPATHY -- DIABETIC FOOT ULCERS -- WOUND HEALING -- CONCLUSIONS -- References -- Chapter 16 - An Overview of Gestational Diabetes -- INTRODUCTION -- PATHOPHYSIOLOGY -- EPIDEMIOLOGY -- SCREENING AND DIAGNOSIS -- EFFECTS OF UNTREATED GESTATIONAL DIABETES -- EFFECTIVENESS OF TREATMENT -- GLUCOSE MONITORING -- LIFESTYLE MODIFICATION-DIET AND EXERCISE -- INSULIN THERAPY -- ORAL HYPOGLYCEMIC AGENTS -- FETAL SURVEILLANCE -- TIMING AND MODE OF DELIVERY
FOLLOW-UP TESTING AND LONG-TERM IMPLICATIONS -- SUMMARY -- References -- SECTION III- MOLECULAR INSIGHTS OF DIABETES AND METABOLIC SYNDROME -- Chapter 17 - Gene-Environment Interaction in the Pathogenesis of Type 2 Diabetes -- INTRODUCTION -- THE GENETIC COMPONENT -- THE ENVIRONMENTAL COMPONENT -- EPIGENETICS -- CONCLUSION -- References -- Chapter 18 - Epigenetics in the Pathophysiology of Type 2 Diabetes -- INTRODUCTION -- AN OVERVIEW OF EPIGENETIC MECHANISMS -- EPIGENETIC MODIFICATIONS IN PATIENTS WITH TYPE 2 DIABETES -- AGING AND EPIGENETIC MODIFICATIONS -- ENVIRONMENTAL FACTORS AND EPIGENETIC IMPACT ON TYPE 2 DIABETES -- INTRAUTERINE ENVIRONMENT AND EPIGENETIC MODIFICATIONS -- GENETICS AND EPIGENETIC MODIFICATIONS -- SUMMARY -- References -- Chapter 19 - Targeting the Metabolic Syndrome and Type 2 Diabetes by Preventing Inflammation -- INTRODUCTION -- IL-1β LINKS OBESITY AND DIABETES -- ACTIVATION OF THE NLRP3 INFLAMMASOME IN FAT, LIVER AND ISLETS RESULTS IN IL-1β PRODUCTION -- IL-1β AND β-CELL TRANSCRIPTIONAL REGULATION -- IL-1β AND GENETIC PREDISPOSITION -- THE DYSBALANCE OF IL-1β AND IL-1RA IN DIABETES54 -- BLOCKING IL-1β SIGNALS IN VIVO INHIBITS DIABETES PROGRESSION54 -- References -- Chapter 20 - Interleukin-18 in Metabolic Syndrome and Diabetes -- INTRODUCTION -- THE BIOLOGICAL EFFECT OF INTERLEUKIN-18 DEPENDS ON THE LOCAL CYTOKINE MILIEU -- INTERLEUKIN-18 IS CLOSELY ASSOCIATED WITH THE METABOLIC SYNDROME AND ITS COMPONENTS -- INTERLEUKIN-18 IS ASSOCIATED WITH THE INITIATION AND COMPLICATIONS OF DIABETES -- INTERLEUKIN-18 AND CARDIOVASCULAR DISEASE -- POTENTIAL MECHANISMS FOR THE ROLE OF INTERLEUKIN-18 IN DIABETES, METABOLIC SYNDROME AND ATHEROSCLEROSIS -- INTERLEUKIN-18 AND EFFECT OF LIFESTYLE INTERVENTIONS -- CONCLUSIONS -- References -- SECTION IV- PATHOPHYSIOLOGY -- Chapter 21 - Sleep, Hypertension, and Diabetes
BACKGROUND AND INTRODUCTION -- SLEEP AND HYPERTENSION -- SLEEP AND PULMONARY ARTERIAL HYPERTENSION (PAH) -- MECHANISMS -- SLEEP AND TYPE 2 DIABETES -- MECHANISMS -- SLEEP, PREGNANCY-INDUCED HYPERTENSION, PRE-ECLAMPSIA, AND GESTATIONAL DIABETES -- PREVENTION AND PUBLIC HEALTH IMPORTANCE -- CONCLUSIONS -- References -- Chapter 22 - Roles of Pancreatic Cell Functions, Liver, Skeletal Muscle, and Adipose Tissues in Diabetes and Metabolic Syndrome -- INTRODUCTION -- ADIPOSE TISSUE -- WHY IS VISCERAL FAT MORE METABOLICALLY DANGEROUS? -- LIVER -- SKELETAL MUSCLE -- PANCREAS -- SUMMARY -- KEY CONCEPTS (FIGURE 22.4) -- References -- Chapter 23 - Liver Disease: A Neglected Complication of Diabetes Mellitus -- INTRODUCTION -- NON-ALCOHOLIC FATTY LIVER DISEASE: CURRENT CONCEPTS AND NATURAL HISTORY -- INTRODUCING LIVER CHECK-UP IN DIABETES -- CONCLUSIONS AND FUTURE PROSPECTS -- References -- SECTION V- PREVENTION AND TREATMENT 1: DIET, EXERCISE, SUPPLEMENTS AND ALTERNATIVE MEDICINES -- Chapter 24 - Antioxidants, Healthy Diet, and Diabetes: Oxidative Stress and Nutrition in Diabetes -- INTRODUCTION -- WHAT IS OXIDATIVE STRESS? ROS AND RNS -- GENERAL ASPECTS OF ANTIOXIDANT THERAPY -- ANTIOXIDANT MOLECULES AND DIABETES -- HEALTHY DIET -- References -- Chapter 25 - Molecular Mechanisms of Diabetes Prevention by Structurally Diverse Antioxidants -- INTRODUCTION -- ROS-MEDIATED MECHANISMS OF T2DM -- MOLECULAR MECHANISMS AND THERAPEUTIC POTENTIAL OF CHOSEN ANTIOXIDANTS -- CONCLUSIONS -- References -- Chapter 26 - Cardioprotective Roles of Selenium in Diabetes -- INTRODUCTION: SELENIUM AND SELENOPROTEINS -- SELENIUM EFFECTS ON THE CONTROL OF CARDIAC ACTIVITY -- EFFECTS OF SELENIUM SUPPLEMENTATION IN DIABETIC HEARTS -- CONCLUDING REMARKS -- References -- Chapter 27 - Exercise and Physical Activity in the Prevention of Diabetes and Metabolic Syndrome -- DIABETES
PREDIABETES
Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years, and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over 92 billion in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant-rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension and clotting abnormalities. Hypertension and dyslipidemia in diabetic patients produces substantial decreases in cardiovascular and microvascular diseases. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome provides an overview of the current epidemic, outlines the consequences of this crisis and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. The contributing experts from around the world give this book relevant and up-to-date global approaches to the critical consequences of metabolic syndrome and make it an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions plus both Type I and Type II Diabetes Presents both prevention and treatment options
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Link Print version: Bagchi, Debasis Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome San Diego : Elsevier Science & Technology,c2012 9780123850836
Subject Diabetes -- Nutritional aspects.;Diabetes -- Treatment.;Metabolic syndrome -- Nutritional aspects.;Metabolic syndrome -- Treatment
Electronic books
Alt Author Nair, Sreejayan
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