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Title Stem cell and gene therapy for cardiovascular disease [electronic resource] / edited by Emerson C. Perin ... [et al.]
Imprint Amsterdam ; Boston : Academic Press, c2015
book jacket
Descript 1 online resource (xxii, 515 p.) : ill. (chiefly col.)
Note Includes bibliographical references and index
Part I. Stem Cells: Introduction and overview of stem cells -- Pathological assessment of experimental models ofstem cell and other regenerative therapies -- Large animalmodels for cardiac cell therapy -- Role of paracrine mechanisms -- Impact of telomere shortening with age in stem cell therapy: new strategies to increase telomere length -- Peripheral arterial disease -- Cell therapy for refractory angina -- Stem cell therapy for acute myocardial infarction: the European experience -- Acute myocardial infarction: the United States experience -- Autologous bone marrow cells for chronic ischemic heart failure -- Adipose-derived stem cells -- Mesenchymal stem cells -- Allogeneic versus autologous source: comparative effects -- Allogeneic alternatives to autologous bone marrow: the MSC clinical trials of acute MI with MSCs -- Allogenic alternatives to autologous bone marrow: the MSC combined cell strategies -- Therapy with c-kit cardiac stem cells for ischemic cardiomyopathy -- Cardiosphere-derived cells -- Cardiovascular regenerative cell therapy using umbilical cord and endometrial cells -- Cardiopoietic stem cells for heart failure therapy -- Transformation to inductible pluripotent stem cells -- Multipotent adult progenitor cells (MAPCs) for cardiovascular and neurologic diseases
Intravenous, intracoronary, transendocardial, and advential delivery -- Retrograde coronary sinus delivery for cardiac cell therapy -- Part II. Tissue Engineering: Current perspectives on methods for administering human pluripotent stem cell-derived cells for myocardial repair -- Acellular injectable biomaterials for treating cardiovascular disease -- Scaffold-based cell delivery forcardiac repair -- Biomaterial: alginate -- Organogenesis -- Part III. Gene Therapy: Gene therapy for cardiovascular diseases -- SERCA2a gene therapy for heart failure -- SDF-1 for cardiac repair -- Gene therapy in critical limb ischemia -- Use of gene modified stem cells for acute myocardial infarction -- Part IV. Future Directions: The history and future of the cardiovascular cell therapy research network -- Signature of responders - lessons fromclinical samples -- Adjunctive therapies with LVADs: combining biological and mechanical regenerative therapies-- Trials in non-ischemic heart failure -- New strategies to enhance stem cell homing for tissue repair -- Cell therapy in ischemic stroke
Subject Cardiovascular system -- Diseases -- Treatment
Cardiovascular system -- Diseases -- Gene therapy
Stem cells
Cardiovascular Diseases -- therapy
Stem Cell Transplantation
Genetic Therapy
Stem Cells
Alt Author Perin, Emerson C
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