| Descript |
1 online resource (xxi, 467 p.) : ill |
| Note |
Includes bibliographical references and index |
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New Insights into the Extracellular Matrix. -- Dynamic Regulation of Basement Membrane Collagen IV Gene Expression in Malignant Tumors. -- Regulation of Phenotypes of Human AortaEndothelial Cells and Smooth Muscle Cells in Culture by Type IV Collage Aggregates. -- Functions of Proteoglycan/Glycosaminoglycan in Liver; SPARC, A Matricellular Protein that Regulates Cell-Matrix Interaction: Implications for Vascular and Connective Tissue Biology. -- Cells Responsible for ECM Production in the Liver. Different Hepatic Cell Populations of the Fibroblast Lineage with Fibrogenic Potential. -- Role of Sinusoidal Endothelial Cells in Liver Inflammation and Repair. -- Molecular Mechanism of Stellate Cell Activation and ECM Remodeling. -- Role of Histone Deacetylases in Transcriptional Control of the Hepatic Stellate Cell Phenotype. Knockout Mice of Matrix Metalloproteinase Genes. Stem Cells Expressing MMP-13 mRNA Appear During Regression Reversal of Hepatic Cirrhosis |
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Extracellular Matrix of the Liver addresses the basic science of the extracellular matrix and discusses new strategies for the treatment of cirrhosis of the liver, with a primary focus on possible gene therapy approaches. The chapters are divided into six sections as follows: * Basic Science of Extracellular Matrix * Cells Responsible for Extracellular Matrix Production * Activation Mechanism of Hepatic Cells and Signal Transduction * Basic Science for Extracellular Matrix Metabolism including Enzymes and their Inhibitors * Matrix Mettaloproteinases and Tissue Inhibitors for Matrix Mettaloproteinases * New Strategies for the treatment of Liver Cirrhosis Key Features * Discusses the possibility of gene therapy for liver cirrhosis * Includes information on new aspects of hepatic stellate cells * Written by top experts in basic science and clinical hepatology |
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Description based on print version record |
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Elsevier |
| Link |
Print version: International Conference on New Strategies for the Treatment of Liver Cirrhosis (2001 : Tokyo, Japan). Extracellular matrix and the liver.
Amsterdam ; Boston : Academic Press, c2003 012525251X 9780125252515
(OCoLC)52342018
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| Subject |
Liver -- Cirrhosis -- Treatment
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Liver -- Cirrhosis -- Gene therapy
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Extracellular matrix
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Liver Cirrhosis -- pathology -- Congresses
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Extracellular Matrix -- genetics -- Congresses
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Liver Cirrhosis -- therapy -- Congresses
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Electronic books
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| Alt Author |
Okazaki, Isao
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