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008    200713s2007    xx      o     ||||0 eng d 
020    9781622575824|q(electronic bk.) 
020    |z9781600215117 
035    (MiAaPQ)EBC3021581 
035    (Au-PeEL)EBL3021581 
035    (CaPaEBR)ebr10683320 
035    (OCoLC)846963227 
040    MiAaPQ|beng|erda|epn|cMiAaPQ|dMiAaPQ 
050  4 RA645.N48 -- H36 2007eb 
082 0  614.5 
100 1  Feigin, Valery L 
245 10 Handbook of Clinical Neuroepidemiology 
264  1 New York :|bNova Science Publishers, Incorporated,|c2007 
264  4 |c©2007 
300    1 online resource (700 pages) 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
505 0  Intro -- HANDBOOK OF CLINICALNEUROEPIDEMIOLOGY -- HANDBOOK
       OF CLINICALNEUROEPIDEMIOLOGY -- LIBRARY OF CONGRESS 
       CATALOGING-IN-PUBLICATION DATA -- CONTENTS -- INTRODUCTION
       -- BASICS OF NEUROEPIDEMIOLOGY -- CHAPTER 1. FUNDAMENTAL 
       STATISTICAL ANDEPIDEMIOLOGICAL CONCEPTS -- ABSTRACT -- 
       INTRODUCTION -- FUNDAMENTALS OF STATISTICS -- Sampling -- 
       Estimation -- Types of Data, Presentation of Data -- 
       SUMMARISING CONTINUOUS DATA -- The Mean, Median and Mode -
       - Measures of Variation -- Summarising Categorical Data --
       Frequency Distributions -- The Normal Distribution and 
       Sampling Distributions -- Standard Normal Distribution -- 
       Standardising -- Statistical Inference -- Sampling 
       Distributions -- Properties of the Sampling Distribution 
       of the Mean -- The Central Limit Theorem -- Confidence 
       Interval for a Mean -- Confidence Interval for a 
       Categorical Variable -- Interpretation of Confidence 
       Intervals -- Hypothesis Testing -- Example -- Two-sided 
       alternative hypothesis -- Results of Hypothesis Testing --
       Type I and Type II Errors -- Significance Levels -- 
       Summary -- EPIDEMIOLOGICAL STUDY DESIGNS -- Experimental 
       Studies -- Parallel versus Crossover Randomized Controlled
       Trials -- Parallel trials can take several difference 
       forms -- Non-Experimental (Observational) Studies -- Rates,
       Ratios, Numerator and Denominator -- Incidence and 
       Prevalence -- Cohort Studies -- Cross-Sectional and Survey
       Studies -- Ecological Studies -- Case-Control Studies -- 
       Case-Reports or Case-Series -- INTERPRETING 
       EPIDEMIOLOGICAL STUDIES -- Sample Size -- Ethical Issues -
       - Summary -- BIAS IN EPIDEMIOLOGICAL STUDY DESIGNS -- 
       Practical Ways to Control for Bias in Non-Experimental 
       Studies -- Example -- Example -- Practical Ways to Control
       for Bias in Experimental Studies -- Mendelian 
       Randomisation Studies -- Summary -- SOME COMMON 
       STATISTICAL TESTS 
505 8  Comparison of Means in Two Related (Paired) Samples - 
       Paired T-Test(One-Sample T-Test) -- Examples -- Comparison
       of the Means of Two Independent Groups - Independent 
       TTest(2-Sample T-Test) -- Examples -- Comparison of 
       Categorical Data -- Comparison of Proportions from Two 
       Independent Groups -- Chi Squared Test -- Comparison of 
       Proportions from Two Related Groups -- Summary -- SOME 
       MORE ADVANCED STATISTICAL TESTS -- Comparison of More Than
       Two Means (ANOVA) -- Assumptions of Analysis of Variance -
       - Transformations -- Transformations to Normalise 
       Distributions -- Transformations to Eliminate 
       Heterogeneity of Variance -- Non-Parametric Tests -- 
       Summary -- CORRELATION -- Pearson Product Moment 
       Correlation Coefficient -- Significance Test for 
       Correlation Coefficient -- Spearman's Rank Correlation 
       Coefficient -- Summary -- REGRESSION BASED METHODS -- 
       Linear Regression -- Multiple Linear Regression -- 
       Multiple Correlation -- Assumptions of Multiple Linear 
       Regression -- Checking the Assumptions -- The Relationship
       between Multiple Regression and ANOVA -- Analysis of 
       Covariance (ANCOVA) -- Logistic Regression -- Survival 
       Times and Cox Regression -- Displaying Survival Times -- 
       Cox Proportional Hazards Regression -- Poisson Regression 
       and Mixed Model Regression -- Effect Modification -- 
       Summary -- CAUSALITY AND CRITICAL APPRAISAL -- Criteria 
       for Causation -- Strength of Evidence for Causality -- 
       Critical Appraisal -- Summary -- META-ANALYSIS -- Meta-
       Analysis of Randomised Controlled Trials -- Meta-Analysis 
       of Non-Randomised Studies -- Summary -- CONCLUSION -- 
       REFERENCES -- RECOMMENDED FURTHER READING -- CLINICAL 
       DISORDERS -- CHAPTER 2. CEREBROVASCULAR DISORDERS -- 
       ABSTRACT -- INTRODUCTION -- INCIDENCE AND PREVALENCE -- 
       Stroke -- Transient Ischemic Attack -- RISK FACTORS -- 
       Medical and Environmental Risk Factors -- Hereditary/
       Genetic Risk Factors 
505 8  Stroke Prevention Strategies -- STROKE OUTCOMES -- 
       Survival -- Functional Outcomes -- MANAGEMENT STRATEGIES -
       - CONCLUSION -- REFERENCES -- RECOMMENDED FURTHER READING 
       -- CHAPTER 3. MIGRAINE -- ABSTRACT -- INTRODUCTION -- CASE
       DEFINITION -- EPIDEMIOLOGY -- Incidence -- Prevalence -- 
       Prevalence by Age and Gender -- Prevalence by Race and 
       Geographic Region -- Prevalence by Socioeconomic Status --
       THE IMPACT OF MIGRAINE -- Societal Impact -- Direct Costs 
       -- Indirect Costs -- Individual Impact -- Attack 
       Characteristics -- Health-Related Quality of Life -- 
       Perspectives on Treatment Options and Cost Effective 
       Intervention -- CONCLUSION -- REFERENCES -- RECOMMENDED 
       FURTHER READING -- CHAPTER 4. EPILEPSY -- ABSTRACT -- 
       INTRODUCTION -- DEFINITIONS OF SEIZURES AND EPILEPSY -- 
       INCIDENCE AND PREVALENCE OF EPILEPSY -- Methodological 
       Issues -- Quality of Epidemiological Reports -- 
       Differentiation between Epilepsy, single Seizures and 
       acute SymptomaticSeizures -- Type of Study -- Population -
       - Selection Criteria -- Epidemiological Surveys in 
       Developing Countries -- Epidemiological Indexes -- 
       INCIDENCE OF EPILEPSY AND UNPROVOKED SEIZURES -- Incidence
       by Age -- Incidence by Gender -- Incidence by Etiology -- 
       Temporal Trends -- Incidence by Seizure Type -- Incidence 
       by Race -- Incidence of Epileptic Syndromes -- Cumulative 
       Incidence -- Incidence by Socio-economic Status -- 
       Incidence and Etiology of Acute Symptomatic and Isolated 
       Seizures -- PREVALENCE OF EPILEPSY -- Prevalence by Age --
       Prevalence by Gender -- Prevalence by Etiology -- 
       Prevalence by Race -- Prevalence by Seizure Type -- 
       Prevalence of Epileptic Syndromes -- Prevalence by Socio-
       economic Class -- ETIOLOGY OF EPILEPSY -- Methodological 
       Issues -- Timing of the Seizure(s) -- Incidence and 
       Prevalence of Acute and Remote Symptomatic Seizures 
       andEpilepsy -- Accuracy and Validity of the Diagnostic 
       Assessment 
505 8  Genetic Epidemiology of Epilepsy -- Mechanisms of 
       Inheritance in Epilepsy -- Acquired Causes of Epilepsy -- 
       Prenatal and Perinatal Risk Factors -- Cerebral Palsy and 
       Mental Retardation -- CNS Infections -- Dementia -- 
       Cerebrovascular Disease -- Vascular Malformations -- 
       Demyelinating Disorders -- Head Trauma -- Brain Tumors -- 
       Neurosurgery -- Effect of Treatment in the Primary 
       Prevention of Seizures and Epilepsy -- Incidence and 
       Common Causes of Acute Symptomatic Seizures -- PROGNOSIS 
       OF EPILEPSY AND EFFICACY OF TREATMENT -- Methodological 
       Issues -- Overall Prognosis of Epilepsy -- Early Prognosis
       of Unprovoked Seizures and Epilepsy -- Prognosis after the
       first Unprovoked Seizure -- Risk Factors for Relapse of a 
       first Unprovoked Seizure -- Treatment, Risk of Recurrence 
       and Long-term Prognosis of a first Seizure -- Prognosis of
       Untreated Epilepsy -- Prognosis of newly Diagnosed 
       Epilepsy -- Principal Prognostic Predictors -- Prognosis 
       of Epilepsy Syndromes -- Antiepileptic Drugs and Seizure 
       Outcome -- Prognosis of Epilepsy after Treatment 
       Withdrawal -- Factors Predicting Seizure Relapse after 
       Treatment Withdrawal -- Psychosocial Outcome -- MORTALITY 
       OF EPILEPSY -- Methodological Issues -- Mortality Rate of 
       Epilepsy -- Overall Mortality in Epilepsy -- Mortality of 
       Epilepsy in Selected Clinical Conditions -- Mortality 
       after a First Seizure -- Predictors of Mortality in 
       Epilepsy -- Mortality in Epilepsy Associated to Selected 
       Clinical Conditions -- Mortality in Developing Countries -
       - CONCLUSIONS -- REFERENCES -- RECOMMENDED FURTHER READING
       -- CHAPTER 5. LOW BACK PAIN -- ABSTRACT -- INTRODUCTION --
       DEFINITION -- INCIDENCE AND PREVALENCE OF LOW BACK PAIN --
       NATURAL HISTORY -- RISK FACTORS -- Individual Risk Factors
       -- Psychosocial Risk Factors -- Occupational Risk Factors 
       -- MANAGEMENT STRATEGIES -- MEDICAL AND SOCIOECONOMIC 
       OUTCOMES -- CONCLUSION 
505 8  REFRENCES -- RECOMMENDED FURTHER READING -- CHAPTER 6. 
       DEMENTIA -- ABSTRACT -- INTRODUCTION -- DEFINITIONS -- 
       VASCULAR CONTRIBUTION TO DEMENTIA -- RISK FACTORS -- 
       TRAUMATIC BRAIN INJURY AS A RISK FACTOR FORALZHEIMER'S 
       DISEASE -- NEUROPSYCHOLOGICAL CONSEQUENCES OF TBI -- POST-
       MORTEM AND HISTOLOGICAL STUDIES -- CONCLUSIONS -- 
       REFERENCES -- RECOMMENDED FURTHER READING -- CHAPTER 7. 
       TRAUMATIC BRAIN INJURY -- ABSTRACT -- INTRODUCTION -- 
       EPIDEMIOLOGY -- Incidence and Mortality Rates -- Causation
       -- Exposure Risk Characteristics -- Classification of 
       Severity -- Mechanisms of Head Injury -- Neuromechanical 
       Aspects -- Neurochemical Aspects -- Imaging and Clinical 
       Neuropathology -- PRIMARY HEAD INJURIES -- Focal Injuries 
       -- Intracranial Hemorrhage -- Diffuse Injuries -- Diffuse 
       Axonal Injury (DAI) -- Secondary Head Injury -- 
       PREHOSPITAL MANAGEMENT -- General and Neurological 
       Examination on Admission -- Neurological Examination -- 
       Associated Systemic Injuries -- Radiological 
       Investigations -- Conservative Versus Surgical Treatment -
       - Neurosurgical Intensive Care -- Neurosurgical Treatment 
       -- Scalp Wounds -- Fractures -- Intracranial Hematomas -- 
       Neurointensive Care Management -- Head Position -- 
       Neurological condition and repeated CT scan -- Oxygenation
       and blood pressure -- Intracranial pressure monitoring -- 
       Cerebral Perfusion Pressure -- Mannitol -- Steroids -- 
       Long-term Neurological Complications -- Infection -- 
       Seizure -- Intracranial Hematomas -- Post-Concussion 
       Syndrome -- Evidence-based Guidelines in Neurotrauma Care 
       -- REHABILITATION -- PROGNOSIS AND OUTCOME -- PREVENTATIVE
       STRATEGY -- CONCLUSION -- REFERENCES -- RECOMMENDED 
       FURTHER READING -- CHAPTER 8. PERIPHERAL NEUROPATHY -- 
       ABSTRACT -- INTRODUCTION -- DEFINITIONS AND EPIDEMIOLOGY 
       OF POLYNEUROPATHIES -- Overall Incidence and Prevalence of
       Peripheral Neuropathy -- GENETIC NEUROPATHIES 
505 8  Charcot Marie Tooth syndrome (also known as hereditary 
       motor/sensoryneuropathies) 
588    Description based on publisher supplied metadata and other
       sources 
590    Electronic reproduction. Ann Arbor, Michigan : ProQuest 
       Ebook Central, 2020. Available via World Wide Web. Access 
       may be limited to ProQuest Ebook Central affiliated 
       libraries 
650  0 Nervous system -- Diseases -- Epidemiology 
655  4 Electronic books 
700 1  Bennett, Derrick A 
776 08 |iPrint version:|aFeigin, Valery L.|tHandbook of Clinical 
       Neuroepidemiology|dNew York : Nova Science Publishers, 
       Incorporated,c2007|z9781600215117 
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