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Author Zimmermann, Richard
Title Nuclear Medicine : Radioactivity for Diagnosis and Therapy
Imprint Les Ulis : EDP Sciences, 2017
©2017
book jacket
Edition 2nd ed
Descript 1 online resource (217 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Hors Collection
Hors Collection
Note Nuclear Medicine Radioactivityfor Diagnosisand TherapyRichard -- CONTENTS -- Preface -- Introduction and Definitions -- 1 Nuclear Medicine, What For? -- I. The Original Case of Thyroid Cancer -- II. The Diagnosis Aspect -- III. The Therapeutic Aspect -- 1. Cancer Therapy -- 2. Non-oncological Therapeutic Application: Rheumatology -- IV. Miscellaneous Aspects of Medical Radioactivity Applications -- 2. A Little History... -- 3. Some Basic Notions of Radiation -- I. Different Types of Radiation -- II. Measurement Units and Doses -- III. Radionuclides for Nuclear Medicine -- 1. Gamma Emitters (γ) -- 2. Positron Emitters (β+) -- 3. Electron Emitters (β-) -- 4. Alpha Emitters (α) -- 5. Radionuclides for Brachytherapy and External Radiotherapy -- 6. Other Radionuclides -- Summary -- 4. SPECT Imaging: -- I. Nuclear Medicine Imaging Methods -- 1. Scintigraphy -- 2. The Products used in Scintigraphy -- II. Imaging Tools -- III. Detection of the Sentinel Node -- Summary -- 5. PET Imaging: Positron Emission Tomography -- I. The Imaging Principle -- II. The Radiation Source -- III. The Labelled Product: Fludeoxyglucose -- IV. Production and Equipment -- V. Applications in Cancerology -- VI. Applications beyond Oncology -- VII. Positron Emitters Evolution -- Summary -- 6. Therapeutic Applications -- I. Metabolic Radiotherapy -- II. Local Radiotherapy -- III. Radioimmunotherapy -- IV. Targeted Radiotherapy -- V. Alphatherapy and Alpha-immunotherapy -- VI. The Theranostic Approach -- VII. Radiotherapeutic Substances -- VIII. The Dose Issue -- IX. Mechanism of Action - The Bystander Effect -- X. The Limitations -- Summary -- 7. The Development -- I. The Molecule Discovery Phase -- II. Pharmacological and Predinical Studies -- III. Pharmacokinetics -- IV. Toxicological Analysis -- V. Phase I Clinical Studies -- VI. Phase II Clinical Studies
VII. Phase III Clinical Studies -- VIII. Regulatory Issues and Registration -- IX. Marketing -- X. Post-marketing Authorisation and Drug Monitoring -- Summary -- 8. The Production of Radiopharmaceuticals -- I. Definitions -- II. Production of Radionuclides -- 1. Reactors -- 2. Particle Accelerators -- 3. Generators -- 4. Fission Products -- III. The Production of Vectors and Ligands -- IV. The Industrial Production of Radiopharmaceuticals -- V. Transport and Logistics -- VI. Radiopharmacies -- VII. Nuclear Medicine Centres in the World -- Summary -- 9. The Future of Nuclear Medicine -- I. Hybrid Imaging Tools and Equipment Evolution -- II. Individualised Medication and the Development of Theranostics -- III. Orphan Diseases and Orphan Drugs -- IV. Ethical and Regulatory Limitations -- 1. Regulation and Administration -- 2. Side Effects and Toxicity -- 3. Dosage and Indication Extensions -- V. Politics and Legislation -- VI. The Future -- Glossary -- For Further Reading -- Hors texte
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Link Print version: Zimmermann, Richard Nuclear Medicine : Radioactivity for Diagnosis and Therapy Les Ulis : EDP Sciences,c2017 9782759821402
Subject Nuclear medicine--Evaluation
Electronic books
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