LEADER 00000cam a2200469Ia 4500 
001    ocn793995928 
003    OCoLC 
005    20130709122628.0 
006    m     o  d         
007    cr ||||||||||| 
008    151013s2012    nju     ob    001 0 eng d 
020    9781118309872 (electronic bk.) 
020    1118309871 (electronic bk.) 
020    9781118309865 (electronic bk.) 
020    1118309863 (electronic bk.) 
020    |z9780470631324 (hbk.) 
020    0470631325 (hbk.) 
020    9781280592386 (MyiLibrary) 
020    1280592389 (MyiLibrary) 
024 8  9786613622211 
035    (OCoLC)793995928|z(OCoLC)805829733 
040    EBLCP|beng|cEBLCP|dOCLCQ|dN|T|dMERUC|dUIU|dDG1|dMYG|dYDXCP
       |dCDX|dOCLCO|dOCLCQ|dOCLCO|dOCLCQ|dCOO|dE7B|dAS 
050  4 QV744 
060 10 QV 744 
082 04 615.19|223 
245 00 Applications of transition metal catalysis in drug 
       discovery and development|h[electronic resource] :|ban 
       industrial perspective /|cedited by Matthew L. Crawley, 
       Barry M. Trost 
260    Hoboken, N.J. :|bJohn Wiley & Sons,|c2012 
300    1 online resource (xviii, 356 p.) 
504    Includes bibliographical references and index 
505 0  Applications of TRANSITION METAL CATALYSIS in Drug 
       Discovery and Development; Contents; Preface; 
       Contributors; About the Authors; 1 Transition Metal 
       Catalysis in the Pharmaceutical Industry; 1.1 Overview of 
       Catalysis; 1.2 Transition Metal Catalysis in the 
       Pharmaceutical Industry; 1.2.1 Cross-Couplings for the 
       Formation of Carbon-Carbon Bonds; 1.2.2 Cross-Couplings 
       for the Formation of Carbon-Heteroatom Bonds; 1.2.3 
       Asymmetric Hydrogenation; 1.2.4 Oxidative Catalysis; 1.2.5
       Asymmetric Addition Reactions; 1.2.6 Metathesis; 1.3 
       Challenges in Taking Catalysis to Industrial Scales 
520    "This book focuses on the drug discovery and development 
       applications of transition metal catalyzed processes, 
       which can efficiently create preclinical and clinical drug
       candidates as well as marketed drugs. The authors pay 
       particular attention to the challenges of transitioning 
       academically-developed reactions into scalable industrial 
       processes. Additionally, the book lays the groundwork for 
       how continued development of transition metal catalyzed 
       processes can deliver new drug candidates. This work 
       provides a unique perspective on the applications of 
       transition metal catalysis in drug discovery and 
       development."--Provided by publisher 
588    Description based on print version record 
650  0 Catalysis 
650  0 Transition metals 
650  0 Pharmacy 
650 12 Drug Discovery 
650 22 Catalysis 
650 22 Pharmaceutical Preparations|xchemistry 
650 22 Transition Elements 
700 1  Crawley, Matthew L 
700 1  Trost, Barry M 
856 40 |uhttp://onlinelibrary.wiley.com/book/10.1002/
       9781118309872|zeBook(Wiley)