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Author Wang, Yuping, MD, author
Title Vascular biology of the placenta [electronic resource] / Yuping Wang
Imprint [San Rafael, California] : Morgan & Claypool, 2017
book jacket
Edition Second edition
Descript 1 PDF (ix, 113 pages) : illustrations
text rdacontent
electronic isbdmedia
online resource rdacarrier
Series Colloquium series on integrated systems physiology, 2154-5626 ; # 75
Colloquium series on integrated systems physiology ; # 75. 2154-5626
Note Part of : Colloquium digital library of life sciences
Includes bibliographical references (pages 89-112)
1. Introduction --
2. Placental blood circulation -- 2.1 Maternal-placental blood circulation -- 2.2 Fetal-placental circulation --
3. Structure of the placenta --
4. Cell types of the placenta -- 4.1 Cytotrophoblasts and syncytiotrophoblasts -- 4.2 Villous core stroma cells -- 4.3 Pericytes -- 4.4 Vascular endothelial cells --
5. Oxygen tension and placental vascular development -- 5.1 Oxygen tension and establishment of maternal-placental circulation -- 5.2 Hypoxia and trophoblast differentiation -- 5.3 Models of placental hypoxia --
6. Vasculogenesis and angiogenesis of human placenta --
7. Angiogenic factors -- 7.1 Vascular endothelial growth factor family molecules and vascular endothelial growth factor receptors -- 7.2 FGFs and FGF receptors -- 7.3 Angiopoietins and tie system --
8. Vasoactivators and placental vasoactivity -- 8.1 Renin- angiotensin system -- 8.2 Arachidonic acid metabolites: thromboxane and prostacyclin -- 8.3 Endothelin-1 and its receptors -- 8.4 Nitric oxide -- 8.5 Chymase -- 8.6 Role of trophoblasts in regulation of placental vasoactivity --
9. Trophoblast-derived extracellular vesicles --
10. Placenta-derived micrornas and immune response in pregnancy --
11. Lymphatic phenotypic characteristics of the human placenta --
12. Placental tissue and cord blood stem cells --
13. Summary -- Acknowledgments -- References -- Author biography
Abstract freely available; full-text restricted to subscribers or individual document purchasers
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The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta
Also available in print
Subject Placenta -- Blood-vessels
Placenta -- blood supply
placenta circulation
vascular development
Electronic books
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