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Author Pennisi, Cristian Pablo
Title The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis
Imprint Aalborg : River Publishers, 2017
©2017
book jacket
Descript 1 online resource (144 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series River Publishers Series in Research and Business Chronicles: Biotechnology and Medicine Ser
River Publishers Series in Research and Business Chronicles: Biotechnology and Medicine Ser
Note Front Cover -- Half Title Page -- RIVER PUBLISHERS SERIES IN RESEARCH AND BUSINESS CHRONICLES: BIOTECHNOLOGY AND MEDICINE -- Full Title - The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis -- Copyright Page -- Contents -- Preface -- List of Contributors -- List of Figures -- List of Tables -- List of Abbreviations -- Chapter 1 - Selective Expansion of Limbal Epithelial Stem Cells in Culture Using Hypoxia -- 1.1 Introduction -- 1.2 Clinical Application of Bioengineered Corneal Epithelial Stem Cell Grafts -- 1.3 Culture Techniques for Bioengineered Stem Cell Sheets -- 1.4 Selective Expansion of LESCs Using Hypoxia -- 1.5 Future Perspectives -- References -- Chapter 2 - Mesenchymal Stem Cells and Pathotropism: Regenerative Potential and Safety Concerns -- 2.1 Introduction -- 2.2 Mesenchymal Stem Cells (MSC) -- 2.2.1 MSC Immunology -- 2.3 MSC in Tumor Support -- 2.3.1 MSC in Drug Delivery to Tumors -- 2.4 Conclusion -- References -- Chapter 3 - Prospective Technologies for Cardiac Repair -- 3.1 Medicine Changing Needs -- 3.2 Additive Technologies in Tissue Engineering -- References -- Chapter 4 - Does Inter-Individual Heterogeneity in the Normal Breast Corrupt Cancer Stem Cell and/or Cancer-Specific Signaling Characterization? -- 4.1 Introduction -- 4.2 Defining Normal Breast Hierarchy -- 4.3 Need for In Vitro Assays to Document Inter-Individual Heterogeneity in the Normal Breast -- 4.4 Future Directions -- Acknowledgements -- References -- Chapter 5 - The Role of Physical Microenvironmental Cues on Myogenesis: Implications for Tissue Engineering of Skeletal Muscle -- 5.1 Introduction -- 5.2 In Vitro Models of Adult Myogenesis -- 5.3 Effect of Soluble and Bound Biochemical Cues -- 5.4 Regulation of Cell Fate by Passive Physical Cues -- 5.4.1 Substrate Topography -- 5.4.2 Substrate Stiffness
5.5 Active Stimulation -- 5.5.1 Electrical Stimulation -- 5.5.2 Mechanical Loading -- 5.6 Summary and Perspectives -- References -- Chapter 6 - Effect of Bioactive Growth Surfaces on Human Mesenchymal Stem Cells: A Pilot Biomarker Study to Assess Growth and Differentiation -- 6.1 Introduction -- 6.2 Materials and Methods -- 6.2.1 Materials -- 6.2.2 Cell Culture Reagents -- 6.2.3 Culture of Human MSCs -- 6.2.4 qPCR for Stem Cell Markers -- 6.3 Results -- 6.4 Discussion -- 6.5 Conclusions -- Acknowledgements -- References -- Chapter 7 - Embryonic Stem Cell Markers in Cancer: Cripto-1 Expression in Glioblastoma -- 7.1 Introduction -- 7.2 Glioma Stem Cells (GSC) -- 7.3 A New Cancer Stem Cell Marker in the Tumor Scaffold -- 7.4 Cr-1 Expression in GBMTissue and the Angiogenic Phenotype -- 7.5 CR-1 Expression Linked to Poorer Prognosis and Shorter Survival -- 7.6 Conclusion -- References -- Chapter 8 Artificial Corneas, and Reinforced Composite Implants for High Risk Donor Cornea Transplantation -- 8.1 Introduction -- 8.1.1 Cornea Transplantation -- 8.2 Artificial Corneas as Prostheses and Regeneration Templates -- 8.2.1 Artificial Corneas as Prostheses -- 8.2.2 Artificial Corneas as Regeneration Templates -- 8.3 Reinforced Collagen Corneal Implants -- 8.3.1 Interpenetrating Networks of Collagen-Phosphorylcholine as Implants -- 8.3.2 RHCIII-MPC Implants in Herpes Simplex Keratitis -- 8.4 Composite Corneal Implants with Peptide and Gene Therapy Capacity -- 8.4.1 LL-37 -- 8.4.2 Implants LL-37 Peptide Release -- 8.4.3 Composite Collagen-Cell-Based Implants -- 8.5 Conclusion -- Ackowledgements -- References -- Chapter 9 - Molecular Mechanisms of Smooth Muscle Cell Differentiation from Adipose-Derived Stem Cell -- 9.1 Introduction -- 9.2 SMC and ASC Characterization -- 9.3 Differentiation of SMC from ASC and Possible Molecular Mechanism
9.4 Conclusion and Perspectives -- 9.5 Conflict of Interest -- References -- Index -- About the Editors -- Back Cover
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Link Print version: Pennisi, Cristian Pablo The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis Aalborg : River Publishers,c2017 9788793379930
Subject Carcinogenesis
Electronic books
Alt Author Prasad, Mayuri Sinha
Rameshwar, Pranela
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