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Author Cho, Seungryong
Title Advanced reconstruction techniques in cone-beam computed tomography for image-guided radiation therapy
book jacket
Descript 198 p
Note Source: Dissertation Abstracts International, Volume: 70-08, Section: B, page: 4977
Advisers: Charles A. Pelizzari; Xiaochuan Pan
Thesis (Ph.D.)--The University of Chicago, 2009
The success of modern radiation therapy such as intensity-modulated radiation therapy (IMRT) or conformal radiation therapy (CRT) is heavily reliant on accurate image guidance in cancer treatment. Cone-beam computed tomography (CBCT) is becoming one of the dominant imaging modalities for image-guidance partly because of its rich image information and its ease of use. However, current technology based on the Feldkamp-Davis-Kress (FDK) algorithm for image reconstruction from a circular scanning trajectory does have more room to improve in terms of image quality and accuracy, although it is often acceptable for certain image-guidance tasks. In addition, the imaging radiation dose is one of the key issues; it has to be minimized or optimized for eventual improvement of radiation therapy via more frequent use of CBCT imaging
Recent progress in image reconstruction algorithm development for CBCT offers the potential for innovations in CBCT for image-guided radiation therapy (IGRT).We have not only contributed to the development of novel reconstruction algorithms, but also applied the new reconstruction techniques to experimental CBCT systems for their potential use in IGRT
We report here innovative CBCT scanning methods and corresponding image reconstruction algorithms that can increase the accuracy of the images and/or reduce the imaging radiation dose from CBCT. Reverse helical CBCT has been proposed and image reconstruction algorithms for the reverse helical scan have been developed and investigated. Region-of-interest imaging methods based on the chord-based reconstruction algorithm have been explored and applied to CBCT. A few-view CBCT approach based on iterative reconstruction algorithms has been studied. Finally, a prototype cone-beam micro-CT system has been developed to provide a testbed for innovative reconstruction techniques
School code: 0330
Host Item Dissertation Abstracts International 70-08B
Subject Engineering, Biomedical
Health Sciences, Radiology
Alt Author The University of Chicago. Medical Physics
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