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020 9781681083858|q(electronic bk.)
020 |z9781681083865
035 (MiAaPQ)EBC4768355
035 (Au-PeEL)EBL4768355
035 (CaPaEBR)ebr11316564
035 (OCoLC)966592191
040 MiAaPQ|beng|erda|epn|cMiAaPQ|dMiAaPQ
050 4 QH447.A584 2016
082 0 572.86
100 1 Lima, Manuela
245 10 Anthropology
250 1st ed
264 1 Oak Park :|bBentham Science Publishers,|c2016
264 4 |c©2016
300 1 online resource (235 pages)
336 text|btxt|2rdacontent
337 computer|bc|2rdamedia
338 online resource|bcr|2rdacarrier
490 1 Anthropology: Current and Future Developments ;|vv.2
505 0 Intro -- CONTENTS -- FOREWORD -- PREFACE -- List of
Contributors -- Human Genomic Projects: Setting the Stage
for Genome-Scale Anthropological Studies -- 1.1. THE
FOUNDATION OF GENOMICS: OVERVIEW OF THE HUMAN GENOME
PROJECT -- 1.2. HUMAN GENOMIC PROJECTS: GENERAL
CHARACTERIZATION AND IMPACT ON BIOLOGICAL ANTHROPOLOGY --
1.2.1. The HapMap Project -- 1.2.2. The ENCyclopedia of
DNA Elements (ENCODE) Project -- 1.2.3. National
Geographic's Genographic Project -- 1.2.4. 1000 Genomes
Project -- 1.2.5. The US National Institutes of Health
(NIH) Roadmap Epigenomics Project -- 1.2.6. Genotype-
Tissue Expression (GTEx) Project -- 1.3. THE NEANDERTHAL
GENOME PROJECT: AN IN-DEPTH JOURNEY INTO OUR PAST -- 1.4.
GENOMICS OF OUR RELATIVES: THE NON-HUMAN PRIMATE GENOME
PROJECTS -- CONCLUDING REMARKS -- CONFLICT OF INTEREST --
ACKNOWLEDGEMENTS -- REFERENCES -- Complete Mitochondrial
DNA through Massively Parallel Sequencing: Methodology and
Applications -- 2.1. INTRODUCTION -- 2.2. MTDNA
CHARACTERISTICS AND APPLICATIONS -- 2.3. AMPLIFICATION
STRATEGIES -- 2.3.1. Long-range PCR -- 2.3.2. Low Template
and Degraded Samples -- 2.3.3. Ancient mtDNA Studies --
2.4. MPS PLATFORMS -- 2.4.1. Illumina MiSeqTM -- 2.4.2.
Ion Torrent Personal Genome Machine (PGM™) -- 2.4.3.
Platforms Comparisons -- 2.5. IMPLEMENTATION OF MPS IN THE
ROUTINE RESEARCH AND DIAGNOSTIC LABORATORIES -- CONCLUDING
REMARKS -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS --
REFERENCES -- Somatic vs Germinal Mutations in
Mitochondrial DNA: Is There Any Relation with Human Health
and Aging? -- 3.1. INTRODUCTION -- 3.2. MATERIAL AND
METHODS -- 3.2.1. Sample Selection -- 3.2.2. MtDNA
Analysis -- 3.2.3. Classification of mtDNA Heteroplasmy in
Somatic or Germinal -- 3.2.4. In Silico Prediction of
Functional Impact of Mutations and Data Analysis -- 3.3.
RESULTS -- 3.3.1. Frequency and Nature of Heteroplasmy
505 8 3.3.2. Functional Impact of Heteroplasmy -- 3.4.
DISCUSSION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS --
REFERENCES -- Human Y Chromosome Mutation Rate: Problems
and Perspectives -- 4.1. INTRODUCTION -- 4.2. THE Y
CHROMOSOME -- 4.3. DATING THE TREE -- 4.4. MUTATION RATES
-- 4.4.1. de novo Mutation Rate -- 4.4.2. Evolutionary
Rate -- 4.4.3. Ancient DNA Based Rate -- 4.5. APPLICATION
TO TWO PUBLIC DATABASES -- 4.5.1. Comparing the Two
Databases -- CONCLUSIVE REMARKS -- CONFLICT OF INTEREST --
ACKNOWLEDGEMENTS -- REFERENCES -- Genomics of Isolated
Populations: Inferences for Gene-Finding Studies -- 5.1.
GENETIC VARIATION AND DISEASE IN HUMAN POPULATIONS -- 5.2.
HUMAN GENETIC ISOLATES: GENERAL CHARACTERISTICS -- 5.3.
THE USE OF POPULATION ISOLATES IN GENE FINDING STUDIES:
ADVANTAGES AND LIMITATIONS -- 5.4. THE GENOMIC ERA AND THE
USE OF ISOLATED POPULATIONS FOR GENE FINDING -- CONCLUDING
REMARKS -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS --
REFERENCES -- Complex Human Phenotypes: The Interplay
between Genes and Environment -- 6.1. INTRODUCTION -- 6.2.
TWIN STUDIES: DISENTANGLING THE INVOLVEMENT OF GENES AND
ENVIRONMENT IN COMPLEX TRAITS -- 6.2.1. Twinning in Human
Populations -- 6.2.2. Twin Studies -- 6.2.3. The
Heritability Concept -- 6.3. GENE-ENVIRONMENT INTERPLAY
MECHANISMS -- 6.3.1. Gene-Environment Interaction --
6.3.1.1. Example 1: Gene-Environment Interaction in Mental
Disorders: The Role of Childhood Maltreatment and MAOA
Gene -- 6.3.1.2. Example 2: Gene-Environment Interaction
in Obesity -- 6.3.2. Gene-Environment Correlation --
6.3.2.1. Example 1: The Role of Both GxE Interaction and
Correlation in the Relationship between Cannabis and
Schizophrenia -- 6.3.2.2. Example 2: Gene-Environment
Correlation: Quantitative and Molecular Genetics Data on
the Role of Genetic Factors in Friendship Selection --
CONCLUDING REMARKS -- CONFLICT OF INTEREST
505 8 ACKNOWLEDGEMENTS -- REFERENCES -- Ancient DNA: From Single
Words to Full Libraries in 30 Years -- 7.1. HISTORY OF
ANCIENT DNA ANALYSIS -- 7.2. ANCIENT DNA FEATURES AND
ENVIRONMENTAL FACTORS -- 7.2.1. Physical and Chemical
Agents Damaging DNA -- 7.2.2. Main Types of Damage --
7.2.3. Contamination and Its Importance in a DNA Work --
7.2.4. Reporting Contamination -- 7.2.5. Decontamination
Methodologies -- CONCLUDING REMARKS -- CONFLICT OF
INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Troubles and
Efficiency of aDNA -- 8.1. AUTHENTICITY CRITERIA -- 8.1.1.
Phylogenetic and Population Meaning: Refining the Criteria
-- 8.1.2. Decontamination: Could it be Achieved? -- 8.2.
INHIBITION AND NATURE OF THE INHIBITORS -- 8.2.1. Avoiding
Inhibition -- 8.3. TISSUES FROM WHERE THE DNA CAN BE
EXTRACTED -- CONCLUDING REMARKS -- CONFLICT OF INTEREST --
ACKNOWLEDGEMENTS -- REFERENCES -- aDNA Methodological
Revolution -- 9.1. EVOLUTION OF THE EXTRACTION METHODS --
9.2. EVOLUTION OF THE SEQUENCING METHODS -- 9.2.1. Next-
Generation Sequencing -- 9.2.2. Enrichment Techniques --
9.2.3. Passing from Second to Third Generation Sequencing
Technologies: Advantages of Single-Stranded Library
Preparation -- 9.3. RECONSIDERING AUTHENTICITY CRITERIA --
CONCLUDING REMARKS AND FUTURE PERSPECTIVES -- CONFLICT OF
INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Complicities
Between Forensic Anthropology and Forensic Genetics: New
Opportunities for Genomics? -- 10.1. INTRODUCTION: MAIN
ATTRIBUTIONS OF FORENSIC ANTHROPOLOGY -- 10.2. WHEN DOES
FORENSIC ANTHROPOLOGY NEEDS GENETICS? -- 10.2.1. To
Determine whether the Remains are Human -- 10.2.2. In
Crime Scenes and Other Particular Scenarios -- 10.2.3.
Performing Sex Diagnosis -- 10.2.4. Performing Ancestry
Analysis -- 10.2.5. Identifying Specific Bacteria --
10.2.6. Performing a Positive Identification
505 8 10.3. AN EMERGENT ROLE FOR GENOMICS IN FORENSIC SCIENCES?
-- CONCLUDING REMARKS -- CONFLICT OF INTEREST --
ACKNOWLEDGEMENTS -- REFERENCES -- SUBJECT INDEX
588 Description based on publisher supplied metadata and other
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590 Electronic reproduction. Ann Arbor, Michigan : ProQuest
Ebook Central, 2020. Available via World Wide Web. Access
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650 0 Genomics
655 4 Electronic books
700 1 Ramos, Amanda
776 08 |iPrint version:|aLima, Manuela|tAnthropology: Current and
Future Developments Volume 2|dOak Park : Bentham Science
Publishers,c2016|z9781681083865
830 0 Anthropology: Current and Future Developments
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