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1st ed |
| Descript |
1 online resource (235 pages) |
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text txt rdacontent |
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computer c rdamedia |
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online resource cr rdacarrier |
| Series |
Anthropology: Current and Future Developments ; v.2 |
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Anthropology: Current and Future Developments
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| Note |
Intro -- CONTENTS -- FOREWORD -- PREFACE -- List of Contributors -- Human Genomic Projects: Setting the Stage for Genome-Scale Anthropological Studies -- 1.1. THE FOUNDATION OF GENOMICS: OVERVIEW OF THE HUMAN GENOME PROJECT -- 1.2. HUMAN GENOMIC PROJECTS: GENERAL CHARACTERIZATION AND IMPACT ON BIOLOGICAL ANTHROPOLOGY -- 1.2.1. The HapMap Project -- 1.2.2. The ENCyclopedia of DNA Elements (ENCODE) Project -- 1.2.3. National Geographic's Genographic Project -- 1.2.4. 1000 Genomes Project -- 1.2.5. The US National Institutes of Health (NIH) Roadmap Epigenomics Project -- 1.2.6. Genotype-Tissue Expression (GTEx) Project -- 1.3. THE NEANDERTHAL GENOME PROJECT: AN IN-DEPTH JOURNEY INTO OUR PAST -- 1.4. GENOMICS OF OUR RELATIVES: THE NON-HUMAN PRIMATE GENOME PROJECTS -- CONCLUDING REMARKS -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Complete Mitochondrial DNA through Massively Parallel Sequencing: Methodology and Applications -- 2.1. INTRODUCTION -- 2.2. MTDNA CHARACTERISTICS AND APPLICATIONS -- 2.3. AMPLIFICATION STRATEGIES -- 2.3.1. Long-range PCR -- 2.3.2. Low Template and Degraded Samples -- 2.3.3. Ancient mtDNA Studies -- 2.4. MPS PLATFORMS -- 2.4.1. Illumina MiSeqTM -- 2.4.2. Ion Torrent Personal Genome Machine (PGM™) -- 2.4.3. Platforms Comparisons -- 2.5. IMPLEMENTATION OF MPS IN THE ROUTINE RESEARCH AND DIAGNOSTIC LABORATORIES -- CONCLUDING REMARKS -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Somatic vs Germinal Mutations in Mitochondrial DNA: Is There Any Relation with Human Health and Aging? -- 3.1. INTRODUCTION -- 3.2. MATERIAL AND METHODS -- 3.2.1. Sample Selection -- 3.2.2. MtDNA Analysis -- 3.2.3. Classification of mtDNA Heteroplasmy in Somatic or Germinal -- 3.2.4. In Silico Prediction of Functional Impact of Mutations and Data Analysis -- 3.3. RESULTS -- 3.3.1. Frequency and Nature of Heteroplasmy |
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3.3.2. Functional Impact of Heteroplasmy -- 3.4. DISCUSSION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Human Y Chromosome Mutation Rate: Problems and Perspectives -- 4.1. INTRODUCTION -- 4.2. THE Y CHROMOSOME -- 4.3. DATING THE TREE -- 4.4. MUTATION RATES -- 4.4.1. de novo Mutation Rate -- 4.4.2. Evolutionary Rate -- 4.4.3. Ancient DNA Based Rate -- 4.5. APPLICATION TO TWO PUBLIC DATABASES -- 4.5.1. Comparing the Two Databases -- CONCLUSIVE REMARKS -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Genomics of Isolated Populations: Inferences for Gene-Finding Studies -- 5.1. GENETIC VARIATION AND DISEASE IN HUMAN POPULATIONS -- 5.2. HUMAN GENETIC ISOLATES: GENERAL CHARACTERISTICS -- 5.3. THE USE OF POPULATION ISOLATES IN GENE FINDING STUDIES: ADVANTAGES AND LIMITATIONS -- 5.4. THE GENOMIC ERA AND THE USE OF ISOLATED POPULATIONS FOR GENE FINDING -- CONCLUDING REMARKS -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Complex Human Phenotypes: The Interplay between Genes and Environment -- 6.1. INTRODUCTION -- 6.2. TWIN STUDIES: DISENTANGLING THE INVOLVEMENT OF GENES AND ENVIRONMENT IN COMPLEX TRAITS -- 6.2.1. Twinning in Human Populations -- 6.2.2. Twin Studies -- 6.2.3. The Heritability Concept -- 6.3. GENE-ENVIRONMENT INTERPLAY MECHANISMS -- 6.3.1. Gene-Environment Interaction -- 6.3.1.1. Example 1: Gene-Environment Interaction in Mental Disorders: The Role of Childhood Maltreatment and MAOA Gene -- 6.3.1.2. Example 2: Gene-Environment Interaction in Obesity -- 6.3.2. Gene-Environment Correlation -- 6.3.2.1. Example 1: The Role of Both GxE Interaction and Correlation in the Relationship between Cannabis and Schizophrenia -- 6.3.2.2. Example 2: Gene-Environment Correlation: Quantitative and Molecular Genetics Data on the Role of Genetic Factors in Friendship Selection -- CONCLUDING REMARKS -- CONFLICT OF INTEREST |
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ACKNOWLEDGEMENTS -- REFERENCES -- Ancient DNA: From Single Words to Full Libraries in 30 Years -- 7.1. HISTORY OF ANCIENT DNA ANALYSIS -- 7.2. ANCIENT DNA FEATURES AND ENVIRONMENTAL FACTORS -- 7.2.1. Physical and Chemical Agents Damaging DNA -- 7.2.2. Main Types of Damage -- 7.2.3. Contamination and Its Importance in a DNA Work -- 7.2.4. Reporting Contamination -- 7.2.5. Decontamination Methodologies -- CONCLUDING REMARKS -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Troubles and Efficiency of aDNA -- 8.1. AUTHENTICITY CRITERIA -- 8.1.1. Phylogenetic and Population Meaning: Refining the Criteria -- 8.1.2. Decontamination: Could it be Achieved? -- 8.2. INHIBITION AND NATURE OF THE INHIBITORS -- 8.2.1. Avoiding Inhibition -- 8.3. TISSUES FROM WHERE THE DNA CAN BE EXTRACTED -- CONCLUDING REMARKS -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- aDNA Methodological Revolution -- 9.1. EVOLUTION OF THE EXTRACTION METHODS -- 9.2. EVOLUTION OF THE SEQUENCING METHODS -- 9.2.1. Next-Generation Sequencing -- 9.2.2. Enrichment Techniques -- 9.2.3. Passing from Second to Third Generation Sequencing Technologies: Advantages of Single-Stranded Library Preparation -- 9.3. RECONSIDERING AUTHENTICITY CRITERIA -- CONCLUDING REMARKS AND FUTURE PERSPECTIVES -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Complicities Between Forensic Anthropology and Forensic Genetics: New Opportunities for Genomics? -- 10.1. INTRODUCTION: MAIN ATTRIBUTIONS OF FORENSIC ANTHROPOLOGY -- 10.2. WHEN DOES FORENSIC ANTHROPOLOGY NEEDS GENETICS? -- 10.2.1. To Determine whether the Remains are Human -- 10.2.2. In Crime Scenes and Other Particular Scenarios -- 10.2.3. Performing Sex Diagnosis -- 10.2.4. Performing Ancestry Analysis -- 10.2.5. Identifying Specific Bacteria -- 10.2.6. Performing a Positive Identification |
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10.3. AN EMERGENT ROLE FOR GENOMICS IN FORENSIC SCIENCES? -- CONCLUDING REMARKS -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- SUBJECT INDEX |
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Description based on publisher supplied metadata and other sources |
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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries |
| Link |
Print version: Lima, Manuela Anthropology: Current and Future Developments Volume 2
Oak Park : Bentham Science Publishers,c2016 9781681083865
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| Subject |
Genomics
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Electronic books
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| Alt Author |
Ramos, Amanda
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