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Author Williams, Hywel
Title Evidence-Based Dermatology
Imprint Hoboken : John Wiley & Sons, Incorporated, 2014
book jacket
Edition 3rd ed
Descript 1 online resource (682 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Series Evidence-Based Medicine Ser
Evidence-Based Medicine Ser
Note Cover -- Dedication -- Title page -- Copyright page -- Contents -- Contributors -- Foreword -- Preface -- About the companion website -- PART I: The concept of evidence-based dermatology -- CHAPTER 1: The field and its boundaries -- Introduction -- What is special about dermatology? -- A vast array of clinical entities -- Extremely common disorders -- Large variations in terms of health-care organization -- Topical treatment may be possible -- Limitations of clinical research -- Disease rarity -- Patients' preferences -- The use of placebo in randomized control trials -- Long-term outcome of chronic disorders -- Self-control design -- The increasing role of industry-sponsored trials -- The limitations of systematic reviews -- Evidence-based medicine: where do we go from here? -- References -- CHAPTER 2: The rationale for evidence-based dermatology -- What is evidence-based dermatology? -- Definitions -- What evidence-based dermatology is not -- Problems with other sources of evidence -- Personal experience -- Expert opinion -- Uncontrolled data -- The process of evidence-based dermatology -- Step 1: asking an answerable structured question -- Step 2: searching for the best external information -- Step 3: sifting information for relevance and quality -- Step 4: applying the evidence back to the patient -- Step 5: recording the information for the future -- Conclusions -- References -- CHAPTER 3: The role of patient and public involvement in evidence-based dermatology -- Introduction -- The many benefits and roles of patient and public involvement in health care -- The skin shows: it matters psychologically and socially -- Education and information for self-care -- The role of patient support groups -- The rise of internet and social networking -- Patient and public involvement in the research process -- The role of patient support groups
Cochrane systematic reviews -- Priority setting partnerships -- Clinical trials: development, delivery, and dissemination -- Summary -- Acknowledgments -- References -- CHAPTER 4: The Cochrane Skin Group -- Background -- The Cochrane Skin Group -- Types of Cochrane reviews -- Scope of the Cochrane Skin Group -- Editorial process: join the Cochrane Skin Group and publish a high-impact paper! -- Support offered by the Cochrane Skin Group editorial base -- Responsibilities of Cochrane Skin Group author teams -- How do review teams find trials? -- The Cochrane Skin Group Specialized Register -- The Cochrane Library -- The role of consumers -- Impact of our reviews -- Communicating with different audiences -- Co-publication -- Cochrane Skin Group satellites -- Contacting the Cochrane Skin Group editorial base -- References -- PART II: The critical appraisal toolbox -- CHAPTER 5: Formulating well-built clinical questions -- Introduction -- Tips for building well-built clinical questions -- The advantages of well-built clinical questions -- What factors are important in generating well-built questions in a dermatology consultation? -- References -- CHAPTER 6: Finding the best evidence -- References -- CHAPTER 7: The hierarchy of evidence -- References -- CHAPTER 8: Appraising systematic reviews and meta-analyses -- Introduction -- Asking a clear question -- Sources of evidence within a systematic review -- The hazards of "quick" searches -- Publication and selective reporting outcome bias -- Data abstraction -- Pooling results -- Interpretation of the data -- Overviews and network meta-analysis -- References -- CHAPTER 9: How to critically appraise a randomized controlled trial -- The place of randomized controlled trials -- Definitions of quality, validity, and bias -- How to tell a good dermatological randomized controlled trial from a bad one
Quality criteria derived from research -- Additional empirical criteria -- References -- CHAPTER 10: Assessing and explaining the evidence on harms of medical interventions -- Introduction -- Data sources -- The limitation of randomized clinical trials -- The value of suspicion: case reports and case series -- Epidemiological studies: the most comprehensive source of data -- A trend toward changing the surveillance paradigm: proactive pharmacovigilance -- Back to the individual patient -- References -- CHAPTER 11: How to evaluate diagnostic tests -- Introduction -- Critical appraisal of diagnostic studies -- Quality of evidence -- Indices of test accuracy -- Applying evidence about a diagnostic test to the care of individual patients -- References -- CHAPTER 12: What makes a good case series? -- Introduction -- Methodology of case series -- Diagnosis -- Inclusion and exclusion criteria -- Informed consent -- Consecutive cases -- Natural course of the disease -- Dosages -- Outcome measures -- Patient perception -- Safety -- Conclusions -- Acknowledgments -- References -- CHAPTER 13: What makes a good prevalence survey? -- Introduction -- The importance of clear reporting -- Quality criteria -- Specification of the target population -- Employment of adequate sampling methods -- Adequate sample size -- Adequate response rate -- Information on nonresponders -- Valid and repeatable disease definition -- Reduction of observer bias -- Additional criteria -- Specification of inclusion criteria for the study population -- Information on studied individuals -- Measurement with valid instruments -- Correct application of epidemiological terms -- Confidence intervals or standard errors -- Other checklists and scales -- Conclusion -- References -- CHAPTER 14: Critical appraisal of pharmacoeconomic studies -- Introduction -- Cost analysis
Cost-effectiveness analysis -- Cost-utility analysis -- Cost-benefit analysis -- Guidelines for critical appraisal of pharmacoeconomic studies -- Framework -- Data and methods -- Results and discussion -- References -- CHAPTER 15: Comparative effectiveness research: what it is and how to assess its quality -- Why do comparative effectiveness research? -- What is comparative effectiveness research? -- Methods in comparative effectiveness research -- Assessing the quality of comparative effectiveness research -- What makes a good randomized clinical effectiveness trial? -- What makes a good comparative effectiveness research observational study? -- References -- CHAPTER 16: Outcome measures -- Introduction -- What can we do with outcomes? -- Elaborate -- Evaluate -- Select -- Assess (measure) -- Analyze -- Report -- Criticize and use -- Outcomes in dermatology and future directions -- References -- CHAPTER 17: Where does qualitative research fit into evidence-based dermatology? -- Definitions -- Qualitative research and evidence-based medicine -- Measuring disease -- Behavioral effects of disease and treatment -- Stigmatization and coping -- Preferences and treatment adherence -- Communication skill and patient narratives -- Health-care models and organization -- Methods -- Critical appraisal and meta-analysis -- Final remarks -- References -- CHAPTER 18: Applying the evidence back to the patient -- Introduction -- How similar are the study participants to my patient? -- Trial participants are often different from clinic patients -- Groups are different from individuals -- Triumph of the aggregate -- Do the outcomes make sense to me? -- Take care in interpreting composite scales -- Sensitive scales amplify effects -- Too many scales and too many short-term studies -- Look for outcomes that are clinically important -- Magnitude of treatment effects
How big? -- Number needed to treat -- Adverse events -- Trials are not a useful source of rare but serious side effects -- Limitations of aggregate data -- Communicating risks -- Decision-aid approaches to weighing up risks and benefits -- What are the patient's values? -- Values and belief models -- And if the treatment still does not work? -- Conclusions -- References -- PART III: The evidence -- SECTION 1 Common inflammatory skin diseases -- CHAPTER 19: Acne vulgaris -- Background -- Definition -- Incidence/prevalence -- Etiology/risk factors -- Prognosis -- Aims of treatment -- Relevant outcomes -- Search methods -- Questions -- Is there any evidence to support the routine use of skin cleansers and/or abrasives in the management of mild to moderate acne? -- What is the role of topical nonantibiotic agents in the treatment of mild primarily noninflammatory acne? -- What is the role of antibiotics in the management of acne vulgaris? -- What dose of oral antibiotics should be prescribed? -- For how long should antibiotic therapy be continued? -- What is the role of oral isotretinoin in the treatment of severe acne? -- References -- CHAPTER 20: Papulopustular rosacea -- Background -- Definition -- Incidence/prevalence -- Etiology/risk -- Prognosis -- Aims -- Outcomes -- Methods -- Questions -- What are the effects of systemic treatments? -- What are the effects of topical drugs? -- References -- CHAPTER 21: Perioral dermatitis -- Background -- Definition -- Incidence/prevalence -- Etiology -- Prognosis -- Aims of treatment -- Outcomes -- Methods of search -- Questions -- What are the effects of "zero therapy"? -- What are the effects of metronidazole? -- What are the effects of oral tetracyclines? -- What are the effects of topical antibiotics? -- What are the effects of nonfluorinated corticosteroids? -- Other treatment modalities -- Acknowledgments
Be sure your skin-care treatments have strong evidential support Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating people with skin diseases. Beginning with a toolbox introduction to the practice of evidence-based dermatology, it then covers the application of evidence for dermatological treatments across a wide range of ailments, including: Common inflammatory skin diseases Skin cancer, moles and actinic keratoses Infective skin disease, exanthems and infestations Disorders of pigmentation In addition, many of the rarer skin disorders are also included so as to provide comprehensive coverage of the topic. World-leading experts in dermatology follow a clinical approach for each disease, and as well as providing their expert guidance on the description and diagnosis of dermatologic disorders, they also discuss common dilemmas that clinicians face when considering the best approach to patient management.  'Key Points' accompany each chapter to provide a quick review of the most important points. Clinically oriented and practically focused, Evidence-based Dermatology ensures that your treatments are entirely patient-focused and fully supported by the very latest medical evidence
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Link Print version: Williams, Hywel Evidence-Based Dermatology Hoboken : John Wiley & Sons, Incorporated,c2014 9781118357606
Subject Skin Diseases
Electronic books
Alt Author Bigby, Michael
Herxheimer, Andrew
Naldi, Luigi
Rzany, Berthold
Dellavalle, Robert
Ran, Yuping
Furue, Masutaka
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