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作者 Figueredo, Benito
書名 Neuroscience Research Advances
出版項 Hauppauge : Nova Science Publishers, Incorporated, 2009
©2009
國際標準書號 9781614703600 (electronic bk.)
9781606929674
book jacket
說明 1 online resource (261 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
系列 Neuroscience Research Progress
Neuroscience Research Progress
附註 Intro -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Behaviors of Phosphorylated Microtubules-Associated Protein Tau (Tau) - A Role in Neuronal and Glial Apoptosis, White Matter Lesion, Topographical Accentuation and 14-3-3 Protein Expression in of Neurofibrillary Tangles of Alzheimer's Disease and othe... -- Abstract -- Introduction -- Discovery of Alzheimer's NFT Stageing and of Neuropil Threads -- Discovery of Pretangles, Evidence of Evolutionary Stages for NFT and Modification of Extracellular Ghost Tangles -- How is Tau Phosphorylated? -- Immunohistochemistry of NFT in Relation with Different Phosphorylation Sites -- Materials and Methods -- NFT show Topographical Accentuation According to Different Phosphorylation Sites -- Relationship of three NFT Configurations to Phosphorylation Sites. How Do the Phosphorylation Sites of Tau Contribute to Difference in Tangle Configuration Among Pre-NFT, Int-NFT and Ext-NFT? -- Three-Repeat (3R) and Four-Repeat (4R) Tauopathies -- Extracellular Ghost Tangles are 3R, Pretangles are Presumed to be 4R and Intracellular Tangles are Hybrid of 3R and 4R. AT8 is not a Immunolabeling Marker for Pre-NFT and Pre-NFT are 4R Tau and Positive for pSer422 in Alzheimer's Disease -- NFT and Neuronal Apoptosis -- 14-3-3 Proteins and NFT -- White Matter Changes and Subcortical Alzheimer Degeneration. Filling Bodies are Lysosomes -- Glial Apoptosis is Associated with BAP -- Familial AD and Unusual Accentuation of NFT in the Hippocampal Subdivisions -- Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17, PSP and CBD -- References -- Brain Development and Neurodevelopmental Outcome in Infants with Congenital Heart Disease -- Abstract -- Introduction -- 1. Neurodevelopmental Outcomes of Infants with Chd
1.1. Clinical and Radiographic Evidence of Impaired Pre-Operative Neurological Status -- 1.2. Short-Term Neurological Outcome after Surgery -- 1.3. Neurodevelopmental Outcomes for Survivors at School Age and Beyond -- 1.3.1. Neurodevelopmental outcomes in children with single ventricles -- 1.3.2. Neurodevelopmental outcomes in children with transposition of the great arteries -- 1.4. Quality of Life -- 2. Risk Factors for Adverse Neurodevelopmental Outcome -- 2.1. Preoperative Neurological Status -- 2.1.1. Intrauterine factors that impact cerebral blood flow and neurodevelopment -- 2.1.2. Congenital brain and developmental abnormalities -- 2.1.3. Acquired preoperative brain injury -- 2.2. Intraoperative Factors that Impact Neurodevelopmental Outcome -- 2.2.1. Acid-base strategies -- 2.2.2. Hemodilution during bypass -- 2.2.3. Circulatory arrest versus low flow bypass -- 2.3 Post-operative Factors that Impact Neurodevelopmental Outcome -- 3. Neuromonitoring and Neuroprotective Strategies -- 3.1. Peri and Intraoperative Neuroprotective Strategies -- 3.2 Neuromonitoring Techniques -- 3.2.1. Transcranial doppler (TCD) -- 3.2.2. Continuous electroencephalography -- 3.2.3. Near infrared spectroscopy (NIRS) -- 2.2.4. Multi-modal neuromonitoring -- Conclusions -- Acknowledgment -- References -- The Distinct Role of Pin1 in the Development and Treatment of Neurodegenerative Tauopathies -- Abstract -- 1. Introduction -- 2. Tau Phosphorylation at Thr231 -- 3. Post-Phosphorylational Regulation of Tau by Pin1 -- 3.1. Pin1 Binds to and Isomerizes the pThr231-Pro Motif in Tau -- 3.2. Pin1 Restores Phosphorylated Tau Function -- 3.3. Pin1 Prevents Phosphorylated Tau Accumulation -- 4. Protective Impact of Pin1 on Wild-type Tau-induced Tauopathy in Mice and AD -- 5. Aggravating Impact of Pin1 on P301L Tau-Induced Tauopathy in Mice -- 6. Conclusion -- References
A Novel Approach to Memory Neuromodulation Using Music: A Literature Review -- Abstract -- 1. Emotional Arousal and Memory -- 1.1. Underlying Mechanisms -- 1.1.1. The role of noradrenergic modulation -- 1.1.2. Amygdala mediation -- 1.2. Hyperconsolidation of Emotional Stimuli -- 1.3. Moderating Factors -- 2. A Novel Approach to Memory Neuromodulation: Music -- 2.1. Music and Emotion -- 2.2. Music and Cognitive Performance -- 3. Conclusion -- References -- Electroencephalography, Amplitude-Integrated Electroencephalography and Neurodevelopmental Outcome in Premature Infants -- Abstract -- Introduction -- 1.0. Definitions and Basic Principles of EEG/aEEG -- 1.1 General EEG Principles -- 1.2. General aEEG Principles -- 1.3. Use and Limitations of EEG/aEEG in the NICU -- 2.0. Maturational Changes in EEG/aEEG -- 2.1. EEG Maturation in Preterm Infants -- 2.1.1. Interburst intervals (IBI) -- 2.1.2. Periods of continuous EEG activity -- 2.1.3. Synchrony -- 2.1.4. Reactivity -- 2.1.5. EEG waveform patterns[7] -- 2.1.6. Sleep-wake cycling (SWC) -- 2.2. aEEG Maturation in Preterm Infants -- 3.0. EEG/aEEG Abnormalities and Prediction of Neurodevelopmental Outcome -- 3.1. Prognostic Value of EEG in Premature Infants -- 3.1.1. Abnormal waveforms -- 3.1.2. Classification systems for EEG abnormalities in preterm infants -- 3.2. Prognostic Value of aEEG in Premature Infants -- Conclusion -- References -- Tangle Dominant Dementia -- Abstract -- Introduction -- Major Clinical Features of TDD -- General Neuropathology of TDD -- Material and Methods -- Results -- Comparison of Clinical Features -- Comparison of Neuropathologic Features -- Synopsis -- Conclusion -- Note Added in Proof -- References -- Does Exposure to Methylphenidate During Adolescent Affect the Response to Methylphenidate in Adulthood? -- Abstract -- Introduction -- Materials and Methods -- Subjects
Open field apparatus -- Wheel - running apparatus -- Drug -- Experimental Protocol -- Analysis -- Results -- Saline control -- Acute phase - comparing ED2 to ED-1 -- Induction phase - comparing ED-7 to ED-2 -- Expression phase - comparing ED-11 to ED-2 -- Discussion -- References -- The Spatial Patterns of Tau Immunopositive Neuronal Cytoplasmic Inclusions (Nci) in the Tauopathies -- Abstract -- Introduction -- The Tauopathies -- Alzheimer's Disease -- Pick's Disease -- Corticobasal Degeneration -- Progressive Supranuclear Palsy -- Materials And Methods -- Cases -- Tissue Preparation -- Morphometric Methods -- Data Analysis -- Spatial Patterns Exhibited by The Tau Positive Nci -- Conclusion -- Acknowledgments -- References -- camp and Neurodevelopment -- Abstract -- 1. The Cyclic AMP Pathways -- 1.1. The Protein Kinase A -- 1.2. The Exchange Proteins Activated by cAMP -- 1.3. The Cyclic AMP & Calcium Pathways -- 1.4. The Cyclic AMP-Response Element-Binding Protein Activation -- 2. Relationship between Receptors Ontogenesis, cAMP Levels and Neurodevelopment Modulation -- 2.1. Adenosine Receptors Family -- 2.2. Dopamine Receptors Family -- 2.3. Glutamate Receptors Family -- 2.4. Gamma Aminobutyric Acid Receptors Family -- 2.5. Peptide Pituitary Adenylate Cyclase - Activating Polypeptide Receptors Family -- 2.6. Acetylcholine Receptors Family -- 2.7. Melatonin Receptors Family -- 3. Further than Transcriptions Factors -- 4. Conclusion -- References -- Epilepsy and Physical Exercise: Human and Animal Studies -- Abstract -- Introduction -- 1. Overview of Epilepsy -- 2. Epilepsy and Exercise: Human's Studies -- 2.1. Risks of sports participation -- 2.3. Epilepsy and exercise physiology -- 3. Epilepsy and Exercise: Animals' Studies -- 3.1. Animal models of epilepsy -- 3.1.1. Kindling model -- 3.1.2. Pilocarpine model
3.2. Effect of physical exercise in experimental models of epilepsy -- Conclusion -- Acknowledgments -- References -- Understanding Schizophrenia Pathogenesis from Developmental Origins of Health and Disease (DOHaD) -- Abstract -- References -- Index -- Blank Page
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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
鏈接 Print version: Figueredo, Benito Neuroscience Research Advances Hauppauge : Nova Science Publishers, Incorporated,c2009 9781606929674
主題 Brain Diseases
Electronic books
Alt Author Meléndez, Fidel
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