記錄 2 之 2
Record:   Prev Next
作者 Hill, Joseph
書名 Muscle 2-Volume Set : Fundamental Biology and Mechanisms of Disease
出版項 San Diego : Elsevier Science & Technology, 2012
©2012
國際標準書號 9780123815118 (electronic bk.)
9780123815101
book jacket
說明 1 online resource (1468 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
附註 Intro -- MUSCLE: Fundamental Biology and Mechanisms of Disease -- Copyright Page -- Contents -- List of Contributors -- Acknowledgments -- Volume 1 -- Part I Introduction -- Chapter 1 An Introduction to Muscle -- Chapter 2 A History of Muscle -- Part II Cardiac Muscle -- Section A Basic Physiology -- Chapter 3 Cardiac Myocyte Specification and Differentiation -- Chapter 4 Transcriptional Control of Cardiogenesis -- Chapter 5 Cardiomyocyte Ultrastructure -- Chapter 6 Overview of Cardiac Muscle Physiology -- Chapter 7 Ionic Fluxes and Genesis of the Cardiac Action Potential -- Chapter 8 G-Protein-Coupled Receptors in the Heart -- Chapter 9 Receptor Tyrosine Kinases in Cardiac Muscle -- Chapter 10 Communication in the Heart: Cardiokines as Mediators of a Molecular Social Network -- Chapter 11 Calcium Fluxes and Homeostasis -- Chapter 12 Excitation-Contraction Coupling in the Heart -- Chapter 13 Role of Sarcomeres in Cellular Tension, Shortening, and Signaling in Cardiac Muscle -- Chapter 14 Cardiovascular Mechanotransduction -- Chapter 15 Cardiomyocyte Metabolism: All Is in Flux -- Chapter 16 Transcriptional Control of Striated Muscle Mitochondrial Biogenesis and Function -- Chapter 17 Mitochondrial Morphology and Function -- Chapter 18 Genetics and Genomics in Cardiovascular Gene Discovery -- Chapter 19 Cardiovascular Proteomics: Assessment of Protein Post-Translational Modifications -- Section B Adaptations and Response -- Chapter 20 Adaption and Responses: Myocardial Innervations and Neural Control -- Chapter 21 Regulation of Cardiac Systolic Function and Contractility -- Chapter 22 Intracellular Signaling Pathways in Cardiac Remodeling -- Chapter 23 Oxidative Stress and Cardiac Muscle -- Chapter 24 Physiologic and Molecular Responses of the Heart to Chronic Exercise -- Chapter 25 Epigenetics in Cardiovascular Biology
Chapter 26 Cardiac MicroRNAs -- Chapter 27 Protein Quality Control in Cardiomyocytes -- Chapter 28 Cardioprotection -- Chapter 29 Cardiac Fibrosis: Cellular and Molecular Determinants -- Chapter 30 Autophagy in Cardiac Physiology and Disease -- Chapter 31 Programmed Cardiomyocyte Death in Heart Disease -- Chapter 32 Wnt and Notch: Potent Regulators of Cardiomyocyte Specification, Proliferation, and Differentiation -- Section C Myocardial Disease -- Chapter 33 Congenital Cardiomyopathies -- Chapter 34 Genetics of Congenital Heart Disease -- Chapter 35 Mechanisms of Stress-Induced Cardiac Hypertrophy -- Chapter 36 Ischemic Heart Disease -- Chapter 37 The Pathophysiology of Heart Failure -- Chapter 38 The Right Ventricle: Reemergence of the Forgotten Ventricle -- Chapter 39 Mammalian Myocardial Regeneration -- Chapter 40 The Structural Basis of Arrhythmia -- Chapter 41 Molecular and Cellular Mechanisms of Cardiac Arrhythmias -- Chapter 42 Genetic Mechanisms of Arrhythmia -- Chapter 43 Infiltrative and Protein Misfolding Myocardial Diseases -- Chapter 44 Cardiac Aging: From Humans to Molecules -- Chapter 45 Adrenergic Receptor Polymorphisms in Heart Failure -- Chapter 46 Cardiac Gene Therapy -- Chapter 47 Protein Kinases in the Heart: Lessons Learned from Targeted Cancer Therapeutics -- Chapter 48 Cell Therapy for Cardiac Disease -- Chapter 49 Chemical Genetics of Cardiac Regeneration -- Chapter 50 Device Therapy for Systolic Ventricular Failure -- Chapter 51 Novel Therapeutic Targets and Strategies against Myocardial Diseases -- Volume 2 -- Part III Skeletal Muscle -- Section A Basic Physiology -- Chapter 52 Skeletal Muscle Development -- Chapter 53 Skeletal Muscle: Architecture of Membrane Systems -- Chapter 54 The Vertebrate Neuromuscular Junction -- Chapter 55 Neuromechanical Interactions that Control Muscle Function and Adaptation
Chapter 56 Control of Resting Ca -- Concentration in Skeletal Muscle -- Chapter 57 Skeletal Muscle Excitation -- Contraction Coupling -- Chapter 58 The Contractile Machinery of Skeletal Muscle -- Chapter 59 Skeletal Muscle Metabolism -- Chapter 60 Skeletal Muscle Fiber Types -- Section B Adaptations and Response -- Chapter 61 Regulation of Skeletal Muscle Development and Function by microRNAs -- Chapter 62 Musculoskeletal Tissue Injury and Repair: Role of Stem Cells, Their Differentiation, and Paracrine Effects -- Chapter 63 Immunological Responses to Muscle Injury -- Chapter 64 Skeletal Muscle Adaptation to Exercise -- Chapter 65 Skeletal Muscle Regeneration -- Chapter 66 Skeletal Muscle Dystrophin- Glycoprotein Complex and Muscular Dystrophy -- Section C Skeletal Muscle Disease -- Chapter 67 Statin-Induced Muscle Toxicity: Clinical and Genetic Determinants of Risk -- Chapter 68 Myotonic Dystrophy -- Chapter 69 Facioscapulohumeral Muscular Dystrophy: Unraveling the Mysteries of a Complex Epigenetic Disease -- Chapter 70 ECM-Related Myopathies and Muscular Dystrophies -- Chapter 71 Molecular Pathogenesis of Skeletal Muscle Abnormalities in Marfan Syndrome -- Chapter 72 Diseases of the Nucleoskeleton -- Chapter 73 Channelopathies of Skeletal Muscle Excitability -- Chapter 74 Thick and Thin Filament Proteins: Acquired and Hereditary Sarcomeric Protein Diseases -- Chapter 75 Metabolic and Mitochondrial Myopathies -- Section D Therapeutics -- Chapter 76 Gene Therapy of Skeletal Muscle Disorders Using Viral Vectors -- Chapter 77 Cell-Based Therapies in Skeletal Muscle Disease -- Chapter 78 Immunological Components of Genetically Inherited Muscular Dystrophies: Duchenne Muscular Dystrophy and Limb-Girdle Muscular Dystrophy Type 2B -- Chapter 79 Myostatin: Regulation, Function, and Therapeutic Applications
Chapter 80 Insulin-Like Growth Factor I Regulation and Its Actions in Skeletal Muscle Growth and Repair -- Chapter 81 Novel Targets and Approaches to Treating Skeletal Muscle Disease -- Part IV Smooth Muscle -- Section A Basic Physiology -- Chapter 82 Development of the Smooth Muscle Cell Lineage -- Chapter 83 Smooth Muscle Myocyte Ultrastructure and Contractility -- Chapter 84 Potassium, Sodium, and Chloride Channels in Smooth Muscle Cells -- Chapter 85 G-Protein-Coupled Receptors in Smooth Muscle -- Chapter 86 Calcium Homeostasis and Signaling in Smooth Muscle -- Chapter 87 Regulation of Smooth Muscle Contraction -- Section B Heterogeneities -- Chapter 88 Heterogeneity of Smooth Muscle -- Chapter 89 Microcirculation -- Chapter 90 Uterine Smooth Muscle -- Section C Adaptations and Response -- Chapter 91 Oxidative Stress, Endothelial Dysfunction, and Its Impact on Smooth Muscle Signaling -- Chapter 92 Hemodynamic Control of Vascular Smooth Muscle Function -- Chapter 93 Myogenic Tone and Mechanotransduction -- Chapter 94 Cell-Cell Communication Through Gap Junctions -- Chapter 95 Vascular Smooth Muscle Cell Phenotypic Adaptation -- Chapter 96 Molecular Pathways of Smooth Muscle Disease -- Section D Smooth Muscle Disease -- Chapter 97 Genetic Variants in Smooth Muscle Contraction and Adhesion Genes Cause Thoracic Aortic Aneurysms and Dissections and Other Vascular Diseases -- Chapter 98 Vascular Smooth Muscle Cell Remodeling in Atherosclerosis and Restenosis -- Chapter 99 Arterial Hypertension -- Chapter 100 Diabetic Vascular Disease -- Chapter 101 Vascular Mechanisms of Hypertension in the Pathophysiology of Preeclampsia -- Chapter 102 Erectile Dysfunction -- Chapter 103 Smooth Muscle in the Normal and Diseased Pulmonary Circulation -- Chapter 104 Airway Smooth Muscle and Asthma -- Chapter 105 Aging -- Chapter 106 Vascular Calcification
Chapter 107 Smooth Muscle Progenitor Cells: A Novel Target for the Treatment of Vascular Disease? -- Chapter 108 Smooth Muscle: Novel Targets and Therapeutic Approaches -- Glossary -- Index
A valuable study of the science behind the medicine, Muscle: Fundamental Biology and Mechanisms of Disease brings together key leaders in muscle biology. These experts provide state-of-the-art insights into the three forms of muscle--cardiac, skeletal, and smooth--from molecular anatomy, basic physiology, disease mechanisms, and targets of therapy. Commonalities and contrasts among these three tissue types are highlighted. This book focuses primarily on the biology of the myocyte. Individuals active in muscle investigation--as well as those new to the field--will find this work useful, as will students of muscle biology. In the case of hte former, many wish to grasp issues at the margins of their own expertise (e.g. clinical matters at one end; molecular matters at the other), adn this book is designed to assist them. Students, postdoctoral fellows, course directors and other faculty will find this book of interest. Beyond this, many clinicians in training (e.g. cardiology fellows) will benefit. The only resource to focus on science before the clinical work and therapeutics Tiered approach to subject: discussion first of normal muscle function through pathological/disease state changes, and ending each section with therapeutic interventions Coverage of topics ranging from basic physiology to newly discovered molecular mechanisms of muscle diseases for all three muscle types: cardiac, skeletal, and smooth
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
鏈接 Print version: Hill, Joseph Muscle 2-Volume Set : Fundamental Biology and Mechanisms of Disease San Diego : Elsevier Science & Technology,c2012 9780123815101
主題 Muscles.;Muscles -- Physiology
Electronic books
Alt Author Olson, Eric
記錄 2 之 2
Record:   Prev Next