MARC 主機 00000nam  2200301   4500 
001    AAI9905201 
005    20070626071947.5 
008    070626s1998                        eng d 
020    9780599027077 
035    (UnM)AAI9905201 
040    UnM|cUnM 
100 1  Hoge, Garrett Stewart, II 
245 10 (4+2) cycloisomerization reactions:  Achiral and 
       asymmetric catalysis using Rh(I) bisphosphine complexes 
300    187 p 
500    Source: Dissertation Abstracts International, Volume: 59-
       09, Section: B, page: 4812 
500    Chair: Scott R. Gilbertson 
502    Thesis (Ph.D.)--Washington University in St. Louis, 1998 
520    We have developed simple and efficient methodology for 
       catalytic intramolecular (4 + 2) cycloisomerizations 
       (equivalent to the Diels-Alder reaction) of unactivated 
       dienes and dienophiles. A cationic rhodium complex 
       modified with the bisphosphine, diphenylphosphinoethane 
       (DIPHOS), was found to be a catalyst for this 
       transformation at room temperature in methylene chloride. 
       Our success with the achiral DIPHOS ligand has led us to 
       explore an asymmetric variant of the reaction using 
       commercially available chiral bisphosphine ligands 
       substituted for DIPHOS. Initial studies have shown that 
       these reactions can generate high enantiomeric excesses. 
       The development and results of both achiral and asymmetric
       (4 + 2) cycloisomerizations are presented 
590    School code: 0252 
590    DDC 
650  4 Chemistry, Organic 
690    0490 
710 20 Washington University in St. Louis 
773 0  |tDissertation Abstracts International|g59-09B 
856 40 |uhttp://pqdd.sinica.edu.tw/twdaoapp/servlet/
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