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100 1  Jabbour, Nicolas 
245 10 Transfusion-Free Medicine and Surgery 
250    2nd ed 
264  1 Hoboken :|bJohn Wiley & Sons, Incorporated,|c2014 
264  4 |c©2013 
300    1 online resource (378 pages) 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
505 0  Cover -- Title Page -- Copyright -- Contents -- 
       Contributors -- Preface -- Chapter 1 History of blood 
       transfusion and patient blood management -- Introduction -
       - Blood: early beliefs and practice -- Blood transfusion -
       - Transfusion with animal blood -- First human blood 
       transfusion -- Karl Landsteiner to the twenty-first 
       century -- New transfusion issues emerge -- The new 
       paradigm -- References -- Chapter 2 The ethical 
       complexities of transfusion-free medicine, surgery and 
       research -- Introduction -- Ethics and informed consent --
       Children, assent, and consent -- Professionalism and 
       transfusion-free practices -- Jehovah's witnesses -- Organ
       transplantation -- Research ethics -- References -- 
       Chapter 3 Transfusion therapy-Balancing the risks and 
       benefits -- Introduction/overview -- The clinical utility 
       of transfusion therapy -- Red blood cell transfusion -- 
       Platelet transfusions -- Plasma component therapy -- 
       Cryoprecipitate -- Transfusion-related adverse reactions -
       - Hemolytic transfusion reactions -- TRALI -- Sepsis -- 
       Summary and conclusions -- References -- Chapter 4 The 
       physiology of anemia and the threshold for blood 
       transfusion -- Introduction -- Etiologies of anemia -- 
       Physiologic response to anemia -- The transfusion 
       threshold -- Risks of blood transfusion -- Infectious 
       complications -- TRALI -- TACO -- Hemolytic reactions -- 
       Febrile reactions -- Metabolic effects -- Immunological 
       effects -- Summary -- References -- Chapter 5 Blood 
       transfusion in surgery -- Introduction -- The cost-
       effectiveness of blood products: a surgical perspective --
       Pre-operative optimization of the surgical patient -- 
       Intra-operative approach to blood conservation -- A. 
       Surgical judgment -- B. Surgical technique -- C. Intra-
       operative cell salvage (ICS) -- D. Acute normovolemic 
       hemodilution (ANH) -- E. Anesthesia management -- F. 
       Coagulation management 
505 8  Post-operative care -- Trends in transfusion-free surgery 
       -- Conclusion -- References -- Chapter 6 Current view of 
       coagulation system -- Normal hemostasis -- Vascular phase 
       -- Platelet phase -- Coagulation phase -- Fibrin formation
       -- Fibrinolysis -- Regulation of hemostasis -- Abnormal 
       hemostasis -- Congenital hemostatic disorders -- Acquired 
       hemostatic disorders -- Evaluation of hemostasis -- 
       History and physical examination -- Coagulation tests -- 
       Preoperative screening tests -- Thromboelastography -- 
       Rotational thromboelastometry (ROTEM®) -- Management of 
       intraoperative coagulation -- Clinical coagulation -- 
       Coagulation management -- Hemostatic drug therapy -- 
       Prolysins (tPA, urokinase, and streptokinase) -- 
       Antifibrinolytics -- Procoagulants -- Anticoagulants -- 
       References -- Chapter 7 Topical hemostatic agents -- 
       Introduction -- History of hemostatics -- The biology of 
       hemostasis -- Hemostasis in surgery -- Safety of 
       hemostatics -- Topical hemostatics -- Passive agents -- 
       Adhesive hemostatics (fibrin glues) -- Surgical settings -
       - Topical hemostatics (Passive agents) -- Collagen-based 
       products -- Cellulose-based products -- Gelatin agents -- 
       References -- Chapter 8 Intraoperative strategies for 
       transfusion-free medicine -- Introduction -- General 
       considerations -- Autologous blood -- Acute normovolemic 
       (isovolemic) hemodilution -- Preoperative autologous 
       donation -- Intraoperative blood salvage -- Pharmacologic 
       agents for blood conservation -- DDAVP -- Antifibrinolytic
       agents -- Recombinant factor VIIa -- Miscellaneous agents 
       -- Human recombinant erythropoietin -- Controlled 
       hypotension -- Sodium nitroprusside (SNP) -- Calcium 
       channel antagonists -- Summary -- References -- Chapter 9 
       Post-operative management in transfusion-free medicine and
       surgery in the ICU -- Introduction -- Anemia in the ICU --
       Role of transfusion in resuscitation 
505 8  Monitoring the adequacy of oxygenation -- Cardiac output -
       - SvO2 -- O2ER -- Blood lactate -- Regional markers of 
       tissue oxygenation -- Reducing transfusion requirements --
       Reducing phlebotomy losses -- Minimizing oxygen 
       consumption -- Increasing CO and DO2 -- Erythropoietin -- 
       Other factors -- Conclusion -- References -- Chapter 10 
       The changing transfusion practice of neonatal and 
       pediatric surgery -- Introduction -- Transfusion 
       considerations specific to the pediatric population -- 
       Strategies to limit need or transfusion -- Use of 
       recombinant human erythropoietin -- Autotransfusion 
       strategies -- Application of hemostatic agents -- 
       Perioperative approaches -- Physician awareness -- 
       Applications of transfusion-limiting strategies to 
       specific surgical situations -- Neonatal surgery -- 
       Cardiac surgery -- Orthopedic surgery -- Craniosynostosis 
       surgery -- Hepatic surgery -- Burn surgery -- Trauma 
       surgery -- Anemia of prematurity -- Anemia in the PICU -- 
       Anemia of oncologic disease -- Conclusion -- 
       Acknowledgements -- References -- Chapter 11 Current 
       management of anemia in oncology -- Overview -- 
       Epidemiology and pattern of treatment -- Prognostic 
       significance and rationale for correcting anemia in 
       oncology -- Pathophysiology of anemia in cancer patients -
       - Diagnostic evaluation and risk assessment -- Treatment 
       options -- Erythropoiesis stimulating agents (ESAs) -- 
       Physiologic basis for ESA use in oncology -- Benefits of 
       ESAs -- Risks of ESAs -- Iron supplementation with ESA -- 
       Peripheral red blood cell (PRBC) transfusion -- Benefits -
       - Risks -- Trend of increased transfusions because of 
       decreased ESA use -- Current recommendations -- Evolving 
       concepts -- Conclusion -- References -- Chapter 12 
       Artificial blood -- Background -- Basics of blood oxygen 
       transportation -- Defining the need for artificial oxygen 
       carriers -- Hb-based oxygen carriers 
505 8  Perfluorocarbons -- Conclusion -- References -- Chapter 13
       Translational strategies to minimize transfusion 
       requirement in liver surgery and transplantation: 
       Targeting ischemia-reperfusion injury -- Introduction -- 
       Role of ischemia-reperfusion injury in liver surgery and 
       transplantation -- Surgical and pharmacological strategies
       to mimimize I/R injury in liver surgery and 
       transplantation -- Static liver preservation -- 
       Pharmacological treatments -- Machine perfusion -- 
       Normothermic machine perfusion (NMP) -- Hypothermic 
       machine perfusion (HMP) -- Surgical strategies -- 
       Conclusion -- Abbreviations -- References -- Chapter 14 
       Legal and administrative issues related to transfusion-
       free medicine and surgery programs -- Introduction -- 
       History of Jehovah's Witnesses and blood -- Acceptable 
       products, treatments, and procedures -- Autologous 
       procedures and equipment -- Organ transplantation -- 
       Overview of legal principles related to refusal of blood -
       - A. Refusal of blood as life-sustaining treatment -- B. 
       Specific issues related to refusal of blood in J.W. -- 
       Disagreeing family members -- Minors -- Mature and 
       emancipated minors -- Evolution of bloodless programs -- 
       Early pioneers of bloodless medicine and surgery -- 
       Transfusion free "bloodless" program implementation -- 
       Legal structure of bloodless program -- Consent: liability
       of physician and hospital -- Confirming a patient's 
       decision to refuse blood -- Policies and procedures -- 
       Future expansion of transfusion-free programs -- 
       References -- Chapter 15 Basic principles of bloodless 
       medicine and surgery -- Questionnaire -- Index -- EULA 
520    This book aims to be a guide to the practice of blood 
       conservation. The first chapter discusses the legal and 
       administrative aspects of bloodless medicine describing 
       the legal principles and practical issues relatd to 
       refusal of transfusion. The second is on balancing the 
       risks and benefits of transfusion includes clinical 
       vignettes of appropriate and inappropriate transfusion. 
       The remainder of the book covers the principles and 
       practice of bloodless medicine, including a chapter on the
       scientific issues of haemostasis and the investigation of 
       bleeding idsorders. The book concludes with chapters on 
       blood conservation in neonatal and paediatric surgery, the
       costs associated with blood transfusion and the quest for 
       artifical blood. New chapters will be included to address 
       blood utilization in oncology and geriatric patients 
588    Description based on publisher supplied metadata and other
       sources 
590    Electronic reproduction. Ann Arbor, Michigan : ProQuest 
       Ebook Central, 2020. Available via World Wide Web. Access 
       may be limited to ProQuest Ebook Central affiliated 
       libraries 
650  0 Bloodless Medical and Surgical Procedures 
655  4 Electronic books 
776 08 |iPrint version:|aJabbour, Nicolas|tTransfusion-Free 
       Medicine and Surgery|dHoboken : John Wiley & Sons, 
       Incorporated,c2014|z9780470674086 
856 40 |uhttps://ebookcentral.proquest.com/lib/sinciatw/
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