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書名 MRI contrast agents [electronic resource] : from molecules to particles / by Sophie Laurent ... [et al.]
出版項 Singapore : Springer Singapore : Imprint: Springer, 2017
國際標準書號 9789811025297 (electronic bk.)
9789811025273 (paper)
國際標準號碼 10.1007/978-981-10-2529-7 doi
book jacket
說明 vii, 125 p. : ill., digital ; 24 cm
系列 SpringerBriefs in applied sciences and technology, 2191-530X
SpringerBriefs in applied sciences and technology
附註 Nanomaterials in medicine -- Magnetic properties (diamagnetism, paramagnetism, ferromagnetism, ferrimagnetism, antiferromagnetism, superparamagnetism) -- Imaging probes -- Magnetic resonance imaging (MRI) -- Bases of MRI -- MRI contrast agents -- Paramagnetic gadolinium complexes -- Superparamagnetic iron oxide nanoparticles -- Synthesis of magnetic nanoparticles -- Stabilization of magnetic nanoparticles -- Physico-chemical characterization of nanoparticles -- MRI applications -- Conclusions
This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc
Host Item Springer eBooks
主題 Contrast media (Diagnostic imaging)
Biomedical Engineering
Nanotechnology and Microengineering
Molecular Medicine
Medical and Radiation Physics
Alt Author Laurent, Sophie
SpringerLink (Online service)
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