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作者 Sharma, Virender K
書名 Oxidation of Amino Acids, Peptides, and Proteins : Kinetics and Mechanism
出版項 Somerset : John Wiley & Sons, Incorporated, 2012
©2013
國際標準書號 9781118482483 (electronic bk.)
9780470627761
book jacket
版本 1st ed
說明 1 online resource (421 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
系列 Wiley Series of Reactive Intermediates in Chemistry and Biology Ser. ; v.9
Wiley Series of Reactive Intermediates in Chemistry and Biology Ser
附註 Intro -- Title page -- Copyright page -- Dedication -- Contents -- Preface to Series -- Introduction -- 1: Reactive Species -- 1.1 Diseases -- 1.1.1 Neurodegenerative Diseases -- 1.1.2 Metals in Human Diseases -- 1.2 Protein Structure -- 1.2.1 Oxidative Labeling -- 1.2.2 Other Techniques -- 1.3 Reactive Species -- 1.3.1 Halogen Species -- 1.3.2 Oxygen Species -- 1.3.3 Nitrogen Species -- 1.3.4 Sulfur Species -- 1.3.5 High-Valent Cr, Mn, and Fe Species -- 1.4 Reactive Species in Environmental Processes -- 1.4.1 Atmospheric Environment -- 1.4.2 Disinfection By-Products (DBP) -- 1.4.3 Oxidation Processes for Purifying Water -- References -- 2: Acid-Base Properties -- 2.1 Dissociation Constants -- 2.2 Speciation -- 2.2.1 Protonation -- 2.2.2 Metal Complexes -- References -- 3: Halogenated Species -- 3.1 Hypohalogens -- 3.1.1 Hypochlorite -- 3.1.2 Hypobromite -- 3.1.3 Hypothiocyanous -- 3.2 Halamines -- 3.2.1 Hydrolysis of Halamines -- 3.2.2 Halogen Transfer by Halamines -- 3.2.3 Reduction of Halamines -- 3.3 Chlorine Dioxide -- 3.3.1 Generation of ClO2 -- 3.3.2 Decomposition of ClO2 -- 3.3.3 Reactivity of ClO2 -- 3.4 Conclusions -- References -- 4: Reactive Oxygen Species -- 4.1 Superoxide -- 4.1.1 Generation -- 4.1.2 Properties -- 4.1.3 Reactivity -- 4.1.4 Metalloenzymes -- 4.2 Singlet Oxygen -- 4.2.1 Reactivity -- 4.3 Ozone -- 4.3.1 Reactivity -- 4.4 Hydroxyl Radical -- 4.4.1 Generation -- 4.4.2 Reactivity -- 4.5 Conclusions -- References -- 5: Reactive Inorganic Oxy-Species of C, N, S, and P -- 5.1 Carbon Species -- 5.1.1 Carbonate Radical -- 5.1.2 Peroxymonocarbonate -- 5.1.3 Carboxyl Radical -- 5.2 Nitrogen Species -- 5.2.1 Nitrogen Monoxide -- 5.2.2 Nitrogen Dioxide Radical -- 5.2.3 Peroxynitrite -- 5.3 Sulfur Species -- 5.3.1 Oxysulfur Radicals -- 5.4 Phosphorous Species -- 5.4.1 Phosphate Radicals -- 5.5 Conclusions -- References
6: High-Valent Cr, Mn, and Fe Species -- 6.1 Chromium -- 6.1.1 Aqueous Chemistry of Oxo-Cr Compounds -- 6.1.2 Chromium(VI, V, and IV) Complexes -- 6.1.3 Reduction of Cr(VI/V/IV) by Substrates -- 6.1.4 Reactivity of Cr Species -- 6.1.5 Mechanism -- 6.1.6 Carcinogenesis -- 6.1.7 Genotoxicity and Cytotoxicity -- 6.1.8 Conclusions -- 6.2 Manganese -- 6.2.1 Aqueous Chemistry of Oxo-Mn Compounds -- 6.2.2 Reactivity of Complexes of Hypervalent Mn -- 6.2.3 Oxidation by Mn(VII) -- 6.2.4 Conclusions -- 6.3 Iron -- 6.3.1 Iron(IV) and Iron(V) -- 6.3.2 Reactivity of Ferrate(V) and Ferrate(VI) -- 6.3.3 Conclusions -- References -- Index
Explains the role of reactive intermediates in biological systems as well as in environmental remediation With its clear and systematic approach, this book examined the broad range of reactive intermediate that can be generated in biological environments, detailing the fundamental properties of each reactive intermediate. Readers gain a contemporary understanding of how these intermediates react with different compounds, with an emphasis on amino acids, peptides, and proteins. The author not only sets forth the basic chemistry and nature of reactive intermediates, he also demonstrates how the properties of the intermediates presented in the book compare with each other. Oxidation of Amino Acids, Peptides, and Proteins begins with a discussion of radical and non-radical reactive species as well as an exploration of the significance of reactive species in the atmosphere, disinfection processes, and environmental remediation. Next, the book covers such topics as: Thermodynamics of amino acids and reactive species and the effect of metal-ligand binding in oxidation chemistry Kinetics and mechanisms of reactive halogen, oxygen, nitrogen, carbon, sulfur and phosphate species as well as reactive high-valent Cr, Mn, and Fe species Reactivity of the species with molecules of biological and environmental importance Generation of reactive species in the laboratory for kinetics studies Oxidation of amino acids, peptides, and proteins by permanganate, ferryl, and ferrate species Application of reactive species in purifying water and treating wastewater With this book as their guide, readers will be able to assess the overall effects of reactive intermediates in biological environments. Moreover, they'll learn how to apply this knowledge for successful water purification and wastewater treatment
Description based on publisher supplied metadata and other sources
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2020. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
鏈接 Print version: Sharma, Virender K. Oxidation of Amino Acids, Peptides, and Proteins : Kinetics and Mechanism Somerset : John Wiley & Sons, Incorporated,c2012 9780470627761
主題 Oxidation-reduction reaction.;Amino acids -- Metabolism.;Pollutants.;Peptides -- Metabolism.;Proteins -- Metabolism
Electronic books
Alt Author Rokita, Steven E
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