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050  4 QD63.O9 -- S53 2013eb 
082 0  547/.23 
100 1  Sharma, Virender K 
245 10 Oxidation of Amino Acids, Peptides, and Proteins :
       |bKinetics and Mechanism 
250    1st ed 
264  1 Somerset :|bJohn Wiley & Sons, Incorporated,|c2012 
264  4 |c©2013 
300    1 online resource (421 pages) 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
490 1  Wiley Series of Reactive Intermediates in Chemistry and 
       Biology Ser. ;|vv.9 
505 0  Intro -- Title page -- Copyright page -- Dedication -- 
       Contents -- Preface to Series -- Introduction -- 1: 
       Reactive Species -- 1.1 Diseases -- 1.1.1 
       Neurodegenerative Diseases -- 1.1.2 Metals in Human 
       Diseases -- 1.2 Protein Structure -- 1.2.1 Oxidative 
       Labeling -- 1.2.2 Other Techniques -- 1.3 Reactive Species
       -- 1.3.1 Halogen Species -- 1.3.2 Oxygen Species -- 1.3.3 
       Nitrogen Species -- 1.3.4 Sulfur Species -- 1.3.5 High-
       Valent Cr, Mn, and Fe Species -- 1.4 Reactive Species in 
       Environmental Processes -- 1.4.1 Atmospheric Environment -
       - 1.4.2 Disinfection By-Products (DBP) -- 1.4.3 Oxidation 
       Processes for Purifying Water -- References -- 2: Acid-
       Base Properties -- 2.1 Dissociation Constants -- 2.2 
       Speciation -- 2.2.1 Protonation -- 2.2.2 Metal Complexes -
       - References -- 3: Halogenated Species -- 3.1 Hypohalogens
       -- 3.1.1 Hypochlorite -- 3.1.2 Hypobromite -- 3.1.3 
       Hypothiocyanous -- 3.2 Halamines -- 3.2.1 Hydrolysis of 
       Halamines -- 3.2.2 Halogen Transfer by Halamines -- 3.2.3 
       Reduction of Halamines -- 3.3 Chlorine Dioxide -- 3.3.1 
       Generation of ClO2 -- 3.3.2 Decomposition of ClO2 -- 3.3.3
       Reactivity of ClO2 -- 3.4 Conclusions -- References -- 4: 
       Reactive Oxygen Species -- 4.1 Superoxide -- 4.1.1 
       Generation -- 4.1.2 Properties -- 4.1.3 Reactivity -- 
       4.1.4 Metalloenzymes -- 4.2 Singlet Oxygen -- 4.2.1 
       Reactivity -- 4.3 Ozone -- 4.3.1 Reactivity -- 4.4 
       Hydroxyl Radical -- 4.4.1 Generation -- 4.4.2 Reactivity -
       - 4.5 Conclusions -- References -- 5: Reactive Inorganic 
       Oxy-Species of C, N, S, and P -- 5.1 Carbon Species -- 
       5.1.1 Carbonate Radical -- 5.1.2 Peroxymonocarbonate -- 
       5.1.3 Carboxyl Radical -- 5.2 Nitrogen Species -- 5.2.1 
       Nitrogen Monoxide -- 5.2.2 Nitrogen Dioxide Radical -- 
       5.2.3 Peroxynitrite -- 5.3 Sulfur Species -- 5.3.1 
       Oxysulfur Radicals -- 5.4 Phosphorous Species -- 5.4.1 
       Phosphate Radicals -- 5.5 Conclusions -- References 
505 8  6: High-Valent Cr, Mn, and Fe Species -- 6.1 Chromium -- 
       6.1.1 Aqueous Chemistry of Oxo-Cr Compounds -- 6.1.2 
       Chromium(VI, V, and IV) Complexes -- 6.1.3 Reduction of 
       Cr(VI/V/IV) by Substrates -- 6.1.4 Reactivity of Cr 
       Species -- 6.1.5 Mechanism -- 6.1.6 Carcinogenesis -- 
       6.1.7 Genotoxicity and Cytotoxicity -- 6.1.8 Conclusions -
       - 6.2 Manganese -- 6.2.1 Aqueous Chemistry of Oxo-Mn 
       Compounds -- 6.2.2 Reactivity of Complexes of Hypervalent 
       Mn -- 6.2.3 Oxidation by Mn(VII) -- 6.2.4 Conclusions -- 
       6.3 Iron -- 6.3.1 Iron(IV) and Iron(V) -- 6.3.2 Reactivity
       of Ferrate(V) and Ferrate(VI) -- 6.3.3 Conclusions -- 
       References -- Index 
520    Explains the role of reactive intermediates in biological 
       systems as well as in environmental remediation   With its
       clear and systematic approach, this book examined the 
       broad range of reactive intermediate that can be generated
       in biological environments, detailing the fundamental 
       properties of each reactive intermediate. Readers gain a 
       contemporary understanding of how these intermediates 
       react with different compounds, with an emphasis on amino 
       acids, peptides, and proteins. The author not only sets 
       forth the basic chemistry and nature of reactive 
       intermediates, he also demonstrates how the properties of 
       the intermediates presented in the book compare with each 
       other.   Oxidation of Amino Acids, Peptides, and Proteins 
       begins with a discussion of radical and non-radical 
       reactive species as well as an exploration of the 
       significance of reactive species in the atmosphere, 
       disinfection processes, and environmental remediation. 
       Next, the book covers such topics as:   Thermodynamics of 
       amino acids and reactive species and the effect of metal-
       ligand binding in oxidation chemistry Kinetics and 
       mechanisms of reactive halogen, oxygen, nitrogen, carbon, 
       sulfur and phosphate species as well as reactive high-
       valent Cr, Mn, and Fe species Reactivity of the species 
       with molecules of biological and environmental importance 
       Generation of reactive species in the laboratory for 
       kinetics studies Oxidation of amino acids, peptides, and 
       proteins by permanganate, ferryl, and ferrate species 
       Application of reactive species in purifying water and 
       treating wastewater   With this book as their guide, 
       readers will be able to assess the overall effects of 
       reactive intermediates in biological environments. 
       Moreover, they'll learn how to apply this knowledge for 
       successful water purification and wastewater treatment 
588    Description based on publisher supplied metadata and other
       sources 
590    Electronic reproduction. Ann Arbor, Michigan : ProQuest 
       Ebook Central, 2020. Available via World Wide Web. Access 
       may be limited to ProQuest Ebook Central affiliated 
       libraries 
650  0 Oxidation-reduction reaction.;Amino acids -- 
       Metabolism.;Pollutants.;Peptides -- Metabolism.;Proteins -
       - Metabolism 
655  4 Electronic books 
700 1  Rokita, Steven E 
776 08 |iPrint version:|aSharma, Virender K.|tOxidation of Amino 
       Acids, Peptides, and Proteins : Kinetics and Mechanism
       |dSomerset : John Wiley & Sons, Incorporated,c2012
       |z9780470627761 
830  0 Wiley Series of Reactive Intermediates in Chemistry and 
       Biology Ser 
856 40 |uhttps://ebookcentral.proquest.com/lib/sinciatw/
       detail.action?docID=1062208|zClick to View