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書名 Self-assembled molecules - new kind of protein ligands : supramolecular ligands / edited by Irena Roterman, Leszek Konieczny
出版項 Cham : Springer International Publishing : Imprint: Springer, 2018
國際標準書號 9783319656397 (electronic bk.)
9783319656380 (paper)
國際標準號碼 10.1007/978-3-319-65639-7 doi
book jacket
說明 1 online resource (xii, 136 pages) : illustrations, digital ; 24 cm
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
text file PDF rda
附註 Open access
This book is an open access under a CC BY license. The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but "naturally irreversible" complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book
Host Item Springer eBooks
主題 Ligands
Protein binding
Biomedicine general
Protein Science
Protein-Ligand Interactions
Biological Techniques
Alt Author Roterman, Irena, editor
Konieczny, Leszek, editor
SpringerLink (Online service)
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