MARC 主機 00000nam 2200385 4500
001 AAI3173190
005 20080530093139.5
008 080530s2005 eng d
020 9780542105234
035 (UMI)AAI3173190
040 UMI|cUMI
100 1 Shieh, Shwn-Huey
245 14 The influence of patient-dependent delay on staging and
survival in lung cancer in Taiwan
300 144 p
500 Source: Dissertation Abstracts International, Volume: 66-
04, Section: B, page: 2020
500 Major Professor: Janice C. Probst
502 Thesis (Ph.D.)--University of South Carolina, 2005
520 Delay at diagnosis is a harmful problem for the survival
of cancer patients. Patients with delayed diagnosis
develop occult metastases and have a more advanced stage
of disease at diagnosis. Little research has been done on
stage of disease at diagnosis and survival due to patient-
dependent delay. This study investigates the covariates
associated with patient-dependent delay, analyzes the
relationship between patient-dependent delay and staging,
and assesses the survival time of patients with lung
cancer
520 The study consists of 1,300 lung cancer patients from a
medical center hospital in central Taiwan from January 1,
1998 to March, 2003. Data was analyzed using the SAS
system to conduct Cox regression analysis
520 The study finds that symptom recognition (chest pain (P =
0.0021), lost body weight (P = 0.0001), and department (P
= 0.0002)) is significantly associated with patient-
dependent delay. Patients with symptom recognition (chest
pain, body weight loss) obtained medical consultations
more quickly than those who did not recognize chest pain
and body weight loss. Gender, marital status, patient TB
(Tuberculosis) history, patient DM (Diabetes Mellitus)
history and stage of disease were statistically
significant predictors of survival after controlling
simultaneously for all main variables. A more serious
stage of disease at diagnosis tended to be associated with
a lower chance of survival. However, tumor stage at
diagnosis and survival did not appear to be significantly
influenced by patient-dependent delay. Health behaviors,
such as smoking, alcohol and betel-nut consumption, showed
no effect on survival, as well as stage at diagnosis
520 The findings may help policy makers to modify current
policies, focusing on preventive medicine in order to
develop lung cancer education programs aimed at alerting
the public to early warning signs and symptoms of lung
cancer and encourage a health care system focusing on
disease prevention and early detection
590 School code: 0202
590 DDC
650 4 Health Sciences, Public Health
650 4 Health Sciences, Health Care Management
650 4 Health Sciences, Oncology
690 0573
690 0769
690 0992
710 20 University of South Carolina
773 0 |tDissertation Abstracts International|g66-04B
856 40 |uhttp://pqdd.sinica.edu.tw/twdaoapp/servlet/
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